AutismKB 2.0

Annotation Detail for CYP26B1


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Basic Information Top
Gene Symbol:CYP26B1 ( CYP26A2,DKFZp686G0638,MGC129613,P450RAI-2 )
Gene Full Name: cytochrome P450, family 26, subfamily B, polypeptide 1
Band: 2p13.2
Quick LinksEntrez ID:56603; OMIM: 605207; Uniprot ID:CP26B_HUMAN; ENSEMBL ID: ENSG00000003137; HGNC ID: 20581
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult14 / 19391217
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal44 / 336030713
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland2 / 3319760
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain19 / 110098917
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine1 / 2344724
kidney4 / 21177718
larynx0 / 241450 
liver1 / 2077434
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate1 / 1893455
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach0 / 966190 
testis3 / 3304429
thymus5 / 8113161
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219825_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.95
Adipocyte6.05
AdrenalCortex5.7
Adrenalgland4.6
Amygdala31.95
Appendix5.3
AtrioventricularNode4.4
BDCA4+_DentriticCells5.45
Bonemarrow5.2
BronchialEpithelialCells5.15
CD105+_Endothelial5.1
CD14+_Monocytes5.5
CD19+_BCells(neg._sel.)5.45
CD33+_Myeloid6.5
CD34+6.45
CD4+_Tcells5.55
CD56+_NKCells5.85
CD71+_EarlyErythroid4.9
CD8+_Tcells4.7
CardiacMyocytes6.85
Caudatenucleus4.7
Cerebellum211.1
CerebellumPeduncles175
CiliaryGanglion3.65
CingulateCortex6.95
Colorectaladenocarcinoma5.2
DorsalRootGanglion4.15
FetalThyroid5.95
Fetalbrain5.35
Fetalliver4.5
Fetallung4.4
GlobusPallidus4.1
Heart7.3
Hypothalamus5.75
Kidney4.3
Leukemia_chronicMyelogenousK-5624.75
Leukemia_promyelocytic-HL-604.6
Leukemialymphoblastic(MOLT-4)4
Liver7.4
Lung5.6
Lymphnode4.6
Lymphoma_burkitts(Daudi)6.65
Lymphoma_burkitts(Raji)7.4
MedullaOblongata5.05
OccipitalLobe4.8
OlfactoryBulb4.15
Ovary3.55
Pancreas4.3
PancreaticIslet5.6
ParietalLobe5.6
Pituitary6.25
Placenta6.4
Pons5
PrefrontalCortex15.5
Prostate6.05
Salivarygland4.2
SkeletalMuscle6.6
Skin9.9
SmoothMuscle6
Spinalcord5.5
SubthalamicNucleus4.8
SuperiorCervicalGanglion5.9
TemporalLobe5.05
Testis49
TestisGermCell38.2
TestisIntersitial9.6
TestisLeydigCell5.25
TestisSeminiferousTubule8.8
Thalamus5.3
Thymus62.5
Thyroid8.8
Tongue5.2
Tonsil5.1
Trachea7.45
TrigeminalGanglion5.65
Uterus4.25
UterusCorpus4.7
WholeBlood5.75
Wholebrain29.25
colon5.2
pineal_day6.36
pineal_night6.2
retina17.225
small_intestine14.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_220_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.07 ± 0.96
Basal Forebrain1.92 ± 0.15
Basal Part of Pons3.3 ± 0.67
Cerebellar Cortex2.89 ± 0.57
Cerebellar Nuclei2.7 ± 0.79
Claustrum2.5 ± 0.65
Epithalamus1.79 ± 0.97
Frontal Lobe2.18 ± 0.73
Globus Pallidus1.68 ± 0.63
Hypothalamus2.36 ± 0.91
Insula1.91 ± 0.79
Limbic Lobe2.3 ± 0.71
Mesencephalon2.19 ± 0.79
Myelencephalon2.31 ± 0.74
Occipital Lobe2.27 ± 0.77
Parietal Lobe2.43 ± 0.76
Pontine Tegmentum2.13 ± 0.69
Striatum1.52 ± 0.72
Subthalamus2.05 ± 0.76
Temporal Lobe2.63 ± 0.72
Thalamus2.14 ± 0.66
White Matter1.71 ± 0.75
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cyp26b1CBCerebellum3.27
3.44
Cyp26b1CTXCerebral cortex0.75
0.87
Cyp26b1HIPHippocampal region0.74
1.48
Cyp26b1HPFHippocampal formation0.78
1.33
Cyp26b1HYHypothalamus1.05
0.87
Cyp26b1LSXLateral septal complex0.45
0.36
Cyp26b1MBMidbrain1.12
1.8
Cyp26b1MYMedulla1.73
1.56
Cyp26b1OLFOlfactory bulb3.93
3.36
Cyp26b1PPons1.78
2.45
Cyp26b1PALPallidum0.71
0.76
Cyp26b1RHPRetrohippocampal region0.58
0.59
Cyp26b1sAMYStriatum-like amygdalar nuclei1.97
1.66
Cyp26b1STRStriatum0.58
0.47
Cyp26b1STRdStriatum dorsal region0.25
0.22
Cyp26b1STRvStriatum ventral region1.08
0.68
Cyp26b1THThalamus0.43
0.43
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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