AutismKB 2.0

Annotation Detail for NPDC1


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Basic Information Top
Gene Symbol:NPDC1 ( CAB,CAB-,CAB-1,CAB1,DKFZp586J0523 )
Gene Full Name: neural proliferation, differentiation and control, 1
Band: 9q34.3
Quick LinksEntrez ID:56654; OMIM: 605798; Uniprot ID:NPDC1_HUMAN; ENSEMBL ID: ENSG00000107281; HGNC ID: 7899
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst0 / 623190 
fetus31 / 56401254
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult158 / 193912181
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor5 / 34366145
chondrosarcoma8 / 8282396
colorectal tumor11 / 11424696
esophageal tumor0 / 172900 
gastrointestinal tumor11 / 11936992
germ cell tumor5 / 26384518
glioma26 / 106883243
head and neck tumor7 / 13630251
kidney tumor7 / 68959101
leukemia4 / 9584241
liver tumor1 / 9635910
lung tumor7 / 10312767
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal239 / 336030771
ovarian tumor3 / 7668239
pancreatic tumor31 / 104616296
primitive neuroectodermal tumor of the CNS33 / 125680262
prostate cancer16 / 102680155
retinoblastoma3 / 4635664
skin tumor13 / 124949104
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor29 / 90257321
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites2 / 4001549
bladder0 / 297570 
blood5 / 12347840
bone5 / 7165569
bone marrow0 / 488010 
brain147 / 1100989133
cervix11 / 48171228
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye13 / 21105461
heart6 / 8962666
intestine20 / 23447285
kidney11 / 21177751
larynx4 / 24145165
liver1 / 2077434
lung18 / 33697453
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth1 / 6705214
muscle0 / 1077150 
nerve6 / 15768380
ovary8 / 10205178
pancreas42 / 214812195
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland4 / 16585241
placenta15 / 28082553
prostate28 / 189345147
salivary gland0 / 201550 
skin17 / 21057480
spleen5 / 5395292
stomach11 / 96619113
testis29 / 33044287
thymus0 / 811310 
thyroid5 / 47473105
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus37 / 232878158
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218086_at
Cell line Expression level Expression bar
721_B_lymphoblasts13.7
Adipocyte44.3
AdrenalCortex26.5
Adrenalgland23.45
Amygdala450.7
Appendix31.85
AtrioventricularNode28.3
BDCA4+_DentriticCells13.3
Bonemarrow18.55
BronchialEpithelialCells35.5
CD105+_Endothelial26.05
CD14+_Monocytes13.1
CD19+_BCells(neg._sel.)17.75
CD33+_Myeloid20.9
CD34+79.05
CD4+_Tcells109.85
CD56+_NKCells18.6
CD71+_EarlyErythroid35.3
CD8+_Tcells85.75
CardiacMyocytes82.5
Caudatenucleus77.8
Cerebellum85.8
CerebellumPeduncles186.85
CiliaryGanglion29.5
CingulateCortex117.95
Colorectaladenocarcinoma156.8
DorsalRootGanglion39
FetalThyroid32.55
Fetalbrain166.85
Fetalliver18.55
Fetallung36
GlobusPallidus93.25
Heart117.15
Hypothalamus124.7
Kidney8.55
Leukemia_chronicMyelogenousK-56211.8
Leukemia_promyelocytic-HL-6011.85
Leukemialymphoblastic(MOLT-4)10.15
Liver48.95
Lung96
Lymphnode29.6
Lymphoma_burkitts(Daudi)35.75
Lymphoma_burkitts(Raji)26.05
MedullaOblongata58.2
OccipitalLobe107.8
OlfactoryBulb35.95
Ovary25.2
Pancreas31.55
PancreaticIslet91.95
ParietalLobe77.4
Pituitary93.95
Placenta37.65
Pons78.15
PrefrontalCortex319.15
Prostate827.8
Salivarygland17.3
SkeletalMuscle14.05
Skin13.85
SmoothMuscle48.65
Spinalcord78.55
SubthalamicNucleus93
SuperiorCervicalGanglion20.45
TemporalLobe92.85
Testis23.35
TestisGermCell31.65
TestisIntersitial23.6
TestisLeydigCell27.6
TestisSeminiferousTubule20.3
Thalamus59.8
Thymus18
Thyroid80.9
Tongue18.8
Tonsil18.6
Trachea61.55
TrigeminalGanglion31.45
Uterus118.15
UterusCorpus35.65
WholeBlood12.35
Wholebrain204.8
colon38
pineal_day433.08
pineal_night364.06
retina79.425
small_intestine30.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10675_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.05 ± 0.4
Basal Forebrain9.88 ± 0.24
Basal Part of Pons10.21 ± 0.3
Cerebellar Cortex10.39 ± 0.22
Cerebellar Nuclei9.55 ± 0.24
Claustrum9.8 ± 0.27
Epithalamus10.29 ± 0.37
Frontal Lobe10.19 ± 0.33
Globus Pallidus9.27 ± 0.18
Hypothalamus10.38 ± 0.37
Insula10.3 ± 0.2
Limbic Lobe10.23 ± 0.33
Mesencephalon9.96 ± 0.26
Myelencephalon10.07 ± 0.38
Occipital Lobe9.84 ± 0.28
Parietal Lobe9.99 ± 0.33
Pontine Tegmentum9.95 ± 0.38
Striatum9.62 ± 0.35
Subthalamus9.87 ± 0.33
Temporal Lobe10.26 ± 0.31
Thalamus9.89 ± 0.26
White Matter9.26 ± 0.27
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00040441 17 35 51 GHPDVAACPGSLDCALK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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