AutismKB 2.0

Annotation Detail for PANX2


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Basic Information Top
Gene Symbol:PANX2 ( MGC119432,PX2,hPANX2 )
Gene Full Name: pannexin 2
Band: 22q13.33
Quick LinksEntrez ID:56666; OMIM: 608421; Uniprot ID:PANX2_HUMAN; ENSEMBL ID: ENSG00000073150; HGNC ID: 8600
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult14 / 19391217
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal21 / 33603076
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow1 / 4880120
brain15 / 110098913
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine0 / 2344720 
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland6 / 15327139
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach2 / 9661920
testis2 / 3304426
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9185_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.45 ± 0.33
Basal Forebrain8.43 ± 0.23
Basal Part of Pons8.29 ± 0.25
Cerebellar Cortex8.49 ± 0.29
Cerebellar Nuclei7.68 ± 0.44
Claustrum8.04 ± 0.49
Epithalamus7.82 ± 0.25
Frontal Lobe8.02 ± 0.43
Globus Pallidus7.91 ± 0.35
Hypothalamus8.14 ± 0.83
Insula8.35 ± 0.27
Limbic Lobe8.41 ± 0.36
Mesencephalon8.13 ± 0.37
Myelencephalon8.09 ± 0.38
Occipital Lobe8.1 ± 0.25
Parietal Lobe8.05 ± 0.34
Pontine Tegmentum7.94 ± 0.38
Striatum8.05 ± 0.38
Subthalamus7.98 ± 0.17
Temporal Lobe8.3 ± 0.33
Thalamus7.83 ± 0.28
White Matter6.53 ± 0.22
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Panx2CBCerebellum22.46
34.08
Panx2CTXCerebral cortex21.54
17.53
Panx2HIPHippocampal region40.34
67.41
Panx2HPFHippocampal formation33.15
44.52
Panx2HYHypothalamus14.12
13.88
Panx2LSXLateral septal complex9.38
8.14
Panx2MBMidbrain26.81
30.82
Panx2MYMedulla56.13
80.89
Panx2OLFOlfactory bulb21.36
17.57
Panx2PPons43.3
59.59
Panx2PALPallidum21.12
23.64
Panx2RHPRetrohippocampal region25.31
22.07
Panx2sAMYStriatum-like amygdalar nuclei11.89
12.55
Panx2STRStriatum5.49
5.09
Panx2STRdStriatum dorsal region4.07
3.92
Panx2STRvStriatum ventral region6.06
4.91
Panx2THThalamus18.39
18.4
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018