AutismKB 2.0

Annotation Detail for PSKH1


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Basic Information Top
Gene Symbol:PSKH1 ( - )
Gene Full Name: protein serine kinase H1
Band: 16q22.1
Quick LinksEntrez ID:5681; OMIM: 177015; Uniprot ID:KPSH1_HUMAN; ENSEMBL ID: ENSG00000159792; HGNC ID: 9529
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult43 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor10 / 26384537
glioma11 / 106883102
head and neck tumor10 / 13630273
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor1 / 9635910
lung tumor5 / 10312748
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal59 / 336030717
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain18 / 110098916
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye9 / 21105442
heart3 / 8962633
intestine4 / 23447217
kidney4 / 21177718
larynx0 / 241450 
liver3 / 20774314
lung13 / 33697438
lymph0 / 442700 
lymph node2 / 9161021
mammary gland0 / 1532710 
mouth1 / 6705214
muscle0 / 1077150 
nerve1 / 1576863
ovary4 / 10205139
pancreas4 / 21481218
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate5 / 18934526
salivary gland1 / 2015549
skin4 / 21057418
spleen1 / 5395218
stomach3 / 9661931
testis6 / 33044218
thymus0 / 811310 
thyroid8 / 47473168
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213141_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.1
Adipocyte9.3
AdrenalCortex7.5
Adrenalgland6.05
Amygdala5.85
Appendix9.3
AtrioventricularNode5.45
BDCA4+_DentriticCells8.1
Bonemarrow6.85
BronchialEpithelialCells6.9
CD105+_Endothelial7.3
CD14+_Monocytes7.8
CD19+_BCells(neg._sel.)7.75
CD33+_Myeloid9.35
CD34+9.2
CD4+_Tcells8
CD56+_NKCells8.7
CD71+_EarlyErythroid6.8
CD8+_Tcells6.55
CardiacMyocytes9
Caudatenucleus6.45
Cerebellum5.8
CerebellumPeduncles8.15
CiliaryGanglion5.05
CingulateCortex10.4
Colorectaladenocarcinoma7.25
DorsalRootGanglion5.45
FetalThyroid7.05
Fetalbrain7.05
Fetalliver6.2
Fetallung6.05
GlobusPallidus5.3
Heart9.15
Hypothalamus7.85
Kidney5.9
Leukemia_chronicMyelogenousK-5626.45
Leukemia_promyelocytic-HL-606.2
Leukemialymphoblastic(MOLT-4)5.75
Liver9.75
Lung8.05
Lymphnode6.2
Lymphoma_burkitts(Daudi)8.9
Lymphoma_burkitts(Raji)10.05
MedullaOblongata6.6
OccipitalLobe6.5
OlfactoryBulb6.05
Ovary4.75
Pancreas5.8
PancreaticIslet7.7
ParietalLobe8.2
Pituitary8.3
Placenta7.15
Pons11.2
PrefrontalCortex8.7
Prostate8.55
Salivarygland5.8
SkeletalMuscle11.95
Skin5.45
SmoothMuscle7.95
Spinalcord7.95
SubthalamicNucleus6.55
SuperiorCervicalGanglion8.15
TemporalLobe8.9
Testis17.55
TestisGermCell7.05
TestisIntersitial7.8
TestisLeydigCell10.2
TestisSeminiferousTubule11.95
Thalamus7.3
Thymus5.65
Thyroid9.15
Tongue8.8
Tonsil7.65
Trachea5.65
TrigeminalGanglion11.85
Uterus5.45
UterusCorpus7.15
WholeBlood8
Wholebrain5.95
colon6.7
pineal_day8.4
pineal_night8.86
retina10.075
small_intestine5.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7839_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.62 ± 1.03
Basal Forebrain2.01 ± 0.2
Basal Part of Pons1.69 ± 0.36
Cerebellar Cortex2.14 ± 0.79
Cerebellar Nuclei2.34 ± 0.71
Claustrum2.95 ± 0.71
Epithalamus1.97 ± 0.63
Frontal Lobe2 ± 0.68
Globus Pallidus2.75 ± 0.55
Hypothalamus2.19 ± 0.78
Insula2.18 ± 0.98
Limbic Lobe2.06 ± 0.68
Mesencephalon2.3 ± 0.85
Myelencephalon2.16 ± 0.71
Occipital Lobe2.17 ± 0.68
Parietal Lobe2.1 ± 0.77
Pontine Tegmentum2.17 ± 0.65
Striatum2.13 ± 0.59
Subthalamus2.18 ± 0.6
Temporal Lobe1.99 ± 0.68
Thalamus2.04 ± 0.6
White Matter2.63 ± 0.69
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Pskh1CBCerebellum6.44
6.78
Pskh1CTXCerebral cortex6.02
4.1
Pskh1HIPHippocampal region6.8
5.94
Pskh1HPFHippocampal formation6.51
5.29
Pskh1HYHypothalamus3.41
3.06
Pskh1LSXLateral septal complex1.26
1.91
Pskh1MBMidbrain4.08
3.96
Pskh1MYMedulla5.24
5.83
Pskh1OLFOlfactory bulb14.02
10.3
Pskh1PPons6.31
8.68
Pskh1PALPallidum0.84
0.74
Pskh1RHPRetrohippocampal region6.07
4.37
Pskh1sAMYStriatum-like amygdalar nuclei1.7
1.15
Pskh1STRStriatum2.26
1.72
Pskh1STRdStriatum dorsal region1.34
1.01
Pskh1STRvStriatum ventral region6.14
4.12
Pskh1THThalamus2.34
1.78
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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