AutismKB 2.0

Annotation Detail for RAD18


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Basic Information Top
Gene Symbol:RAD18 ( RNF73 )
Gene Full Name: RAD18 homolog (S. cerevisiae)
Band: 3p25.3
Quick LinksEntrez ID:56852; OMIM: 605256; Uniprot ID:RAD18_HUMAN; ENSEMBL ID: ENSG00000070950; HGNC ID: 18278
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst6 / 6231996
fetus27 / 56401247
neonate1 / 3109732
infant0 / 236200 
juvenile5 / 5555689
adult57 / 193912129
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor1 / 1729057
gastrointestinal tumor9 / 11936975
germ cell tumor9 / 26384534
glioma3 / 10688328
head and neck tumor7 / 13630251
kidney tumor0 / 689590 
leukemia8 / 9584283
liver tumor6 / 9635962
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal92 / 336030727
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS10 / 12568079
prostate cancer2 / 10268019
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites4 / 4001599
bladder2 / 2975767
blood1 / 1234788
bone1 / 7165513
bone marrow6 / 48801122
brain14 / 110098912
cervix1 / 4817120
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus1 / 2020949
eye1 / 2110544
heart2 / 8962622
intestine11 / 23447246
kidney10 / 21177747
larynx0 / 241450 
liver7 / 20774333
lung5 / 33697414
lymph0 / 442700 
lymph node3 / 9161032
mammary gland6 / 15327139
mouth3 / 6705244
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta6 / 28082521
prostate3 / 18934515
salivary gland2 / 2015599
skin4 / 21057418
spleen3 / 5395255
stomach4 / 9661941
testis12 / 33044236
thymus5 / 8113161
thyroid3 / 4747363
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus7 / 23287830
vascular9 / 51780173
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_14495_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.34 ± 0.45
Basal Forebrain3.86 ± 0.46
Basal Part of Pons3.97 ± 0.42
Cerebellar Cortex3.83 ± 0.46
Cerebellar Nuclei4.12 ± 0.5
Claustrum4.13 ± 0.67
Epithalamus3.45 ± 0.56
Frontal Lobe3.84 ± 0.52
Globus Pallidus4.13 ± 0.38
Hypothalamus3.63 ± 0.51
Insula4.07 ± 0.52
Limbic Lobe4.22 ± 0.5
Mesencephalon4.05 ± 0.64
Myelencephalon3.97 ± 0.54
Occipital Lobe4.11 ± 0.39
Parietal Lobe4.04 ± 0.57
Pontine Tegmentum4 ± 0.64
Striatum4.23 ± 0.82
Subthalamus4.34 ± 0.66
Temporal Lobe3.99 ± 0.51
Thalamus3.65 ± 0.53
White Matter3.71 ± 0.72
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rad18CBCerebellum8.76
11.64
Rad18CTXCerebral cortex56.77
49.51
Rad18HIPHippocampal region28.47
40.12
Rad18HPFHippocampal formation29.85
35.3
Rad18HYHypothalamus6.54
6.44
Rad18LSXLateral septal complex9.81
8.06
Rad18MBMidbrain10.98
13.92
Rad18MYMedulla11.89
20.06
Rad18OLFOlfactory bulb32.94
30.12
Rad18PPons11.98
19.1
Rad18PALPallidum10.52
11.43
Rad18RHPRetrohippocampal region33.05
28.78
Rad18sAMYStriatum-like amygdalar nuclei27.04
21.55
Rad18STRStriatum41.24
33.16
Rad18STRdStriatum dorsal region51.35
41.86
Rad18STRvStriatum ventral region27.93
21.76
Rad18THThalamus14.99
17.12
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003496 18 278 295 HQEFVHMYNAQCDALHPK Peptide Atlas
RAD18_HUMAN_407 11 407 417 LDSPEELEPDR PRIDE
RAD18_HUMAN_463 11 463 473 NDLQDTEISPR PRIDE
RAD18_HUMAN_90 21 90 110 NHLLQFALESPAKSPASSSSK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018