AutismKB 2.0

Annotation Detail for MDM1


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Basic Information Top
Gene Symbol:MDM1 ( FLJ95264 )
Gene Full Name: Mdm1 nuclear protein homolog (mouse)
Band: 12q15
Quick LinksEntrez ID:56890; OMIM: NA; Uniprot ID:MDM1_HUMAN; ENSEMBL ID: ENSG00000111554; HGNC ID: 29917
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus23 / 56401240
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult150 / 193912177
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor5 / 26384518
glioma0 / 1068830 
head and neck tumor4 / 13630229
kidney tumor3 / 6895943
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal83 / 336030724
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor117 / 125191934
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow2 / 4880140
brain28 / 110098925
cervix0 / 481710 
connective tissue118 / 149255790
ear3 / 16212185
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine0 / 2344720 
kidney5 / 21177723
larynx0 / 241450 
liver4 / 20774319
lung5 / 33697414
lymph1 / 4427022
lymph node1 / 9161010
mammary gland1 / 1532716
mouth5 / 6705274
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta5 / 28082517
prostate3 / 18934515
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach0 / 966190 
testis50 / 330442151
thymus4 / 8113149
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213761_at
Cell line Expression level Expression bar
721_B_lymphoblasts18.7
Adipocyte7.7
AdrenalCortex9.1
Adrenalgland7.4
Amygdala9.8
Appendix22.9
AtrioventricularNode11.55
BDCA4+_DentriticCells30
Bonemarrow9.95
BronchialEpithelialCells6.6
CD105+_Endothelial36.1
CD14+_Monocytes13.15
CD19+_BCells(neg._sel.)19.4
CD33+_Myeloid16.55
CD34+80
CD4+_Tcells29.3
CD56+_NKCells57
CD71+_EarlyErythroid18.15
CD8+_Tcells23.45
CardiacMyocytes11.3
Caudatenucleus7.45
Cerebellum6.2
CerebellumPeduncles10.6
CiliaryGanglion6.5
CingulateCortex8.4
Colorectaladenocarcinoma7.1
DorsalRootGanglion8.95
FetalThyroid7.9
Fetalbrain7.45
Fetalliver7.55
Fetallung6.2
GlobusPallidus6.3
Heart17.05
Hypothalamus13.5
Kidney6.8
Leukemia_chronicMyelogenousK-5626.7
Leukemia_promyelocytic-HL-608.85
Leukemialymphoblastic(MOLT-4)8.5
Liver12.2
Lung7.75
Lymphnode8.85
Lymphoma_burkitts(Daudi)13.2
Lymphoma_burkitts(Raji)12.05
MedullaOblongata6.95
OccipitalLobe6.6
OlfactoryBulb5.55
Ovary7
Pancreas6.45
PancreaticIslet8.3
ParietalLobe9.5
Pituitary12.85
Placenta6.4
Pons8.1
PrefrontalCortex10.65
Prostate8.9
Salivarygland9.8
SkeletalMuscle10.05
Skin7.3
SmoothMuscle8.4
Spinalcord13.45
SubthalamicNucleus7.55
SuperiorCervicalGanglion14.75
TemporalLobe7.5
Testis11.95
TestisGermCell25.9
TestisIntersitial14.3
TestisLeydigCell14.15
TestisSeminiferousTubule9.75
Thalamus8.25
Thymus6.55
Thyroid23.55
Tongue8.85
Tonsil8.05
Trachea6.45
TrigeminalGanglion12.6
Uterus27.9
UterusCorpus9.9
WholeBlood14.5
Wholebrain7
colon21
pineal_day20.6
pineal_night26.58
retina12.025
small_intestine9.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P413180
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.05 ± 1
Basal Forebrain1.47 ± 0.2
Basal Part of Pons1.17 ± 0.36
Cerebellar Cortex1.84 ± 0.64
Cerebellar Nuclei1.99 ± 0.67
Claustrum2.21 ± 0.66
Epithalamus2.51 ± 1.03
Frontal Lobe1.59 ± 0.68
Globus Pallidus1.9 ± 0.51
Hypothalamus1.8 ± 0.67
Insula1.32 ± 0.45
Limbic Lobe1.63 ± 0.62
Mesencephalon1.77 ± 0.67
Myelencephalon1.69 ± 0.63
Occipital Lobe1.71 ± 0.51
Parietal Lobe1.74 ± 0.8
Pontine Tegmentum1.77 ± 0.68
Striatum1.49 ± 0.68
Subthalamus1.69 ± 0.6
Temporal Lobe1.59 ± 0.64
Thalamus1.58 ± 0.61
White Matter2.28 ± 0.75
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mdm1CBCerebellum4.69
5.6
Mdm1CTXCerebral cortex2.16
1.59
Mdm1HIPHippocampal region4.24
4.11
Mdm1HPFHippocampal formation4.66
4.04
Mdm1HYHypothalamus0.2
0.2
Mdm1LSXLateral septal complex0.19
0.15
Mdm1MBMidbrain1.06
1.25
Mdm1MYMedulla5.71
6.3
Mdm1OLFOlfactory bulb2.44
1.63
Mdm1PPons2.08
2.27
Mdm1PALPallidum0.25
0.19
Mdm1RHPRetrohippocampal region5.3
3.93
Mdm1sAMYStriatum-like amygdalar nuclei0.37
0.23
Mdm1STRStriatum1.33
1.17
Mdm1STRdStriatum dorsal region1.73
1.59
Mdm1STRvStriatum ventral region0.67
0.45
Mdm1THThalamus1.82
1.85
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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