AutismKB 2.0

Annotation Detail for UBQLN4


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Basic Information Top
Gene Symbol:UBQLN4 ( A1U,C1orf6,CIP75,UBIN )
Gene Full Name: ubiquilin 4
Band: 1q22
Quick LinksEntrez ID:56893; OMIM: 605440; Uniprot ID:UBQL4_HUMAN; ENSEMBL ID: ENSG00000160803; HGNC ID: 1237
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus36 / 56401263
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult84 / 193912143
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor8 / 9417884
cervical tumor3 / 3436687
chondrosarcoma4 / 8282348
colorectal tumor5 / 11424643
esophageal tumor0 / 172900 
gastrointestinal tumor13 / 119369108
germ cell tumor23 / 26384587
glioma8 / 10688374
head and neck tumor7 / 13630251
kidney tumor5 / 6895972
leukemia2 / 9584220
liver tumor9 / 9635993
lung tumor11 / 103127106
lymphoma12 / 71755167
non-neoplasia3 / 9725030
normal114 / 336030733
ovarian tumor2 / 7668226
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer5 / 10268048
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor13 / 125191103
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder3 / 29757100
blood7 / 12347856
bone1 / 7165513
bone marrow1 / 4880120
brain42 / 110098938
cervix6 / 48171124
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye9 / 21105442
heart10 / 89626111
intestine15 / 23447263
kidney9 / 21177742
larynx0 / 241450 
liver10 / 20774348
lung17 / 33697450
lymph9 / 44270203
lymph node6 / 9161065
mammary gland10 / 15327165
mouth3 / 6705244
muscle10 / 10771592
nerve1 / 1576863
ovary3 / 10205129
pancreas7 / 21481232
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta13 / 28082546
prostate9 / 18934547
salivary gland3 / 20155148
skin7 / 21057433
spleen1 / 5395218
stomach8 / 9661982
testis17 / 33044251
thymus0 / 811310 
thyroid3 / 4747363
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus8 / 23287834
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5053_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4 ± 0.48
Basal Forebrain3.38 ± 0.26
Basal Part of Pons3.63 ± 0.59
Cerebellar Cortex3.5 ± 0.47
Cerebellar Nuclei3.46 ± 0.54
Claustrum3.6 ± 0.66
Epithalamus3.3 ± 0.62
Frontal Lobe3.58 ± 0.48
Globus Pallidus3.62 ± 0.8
Hypothalamus3.65 ± 0.52
Insula3.39 ± 0.45
Limbic Lobe3.73 ± 0.52
Mesencephalon3.66 ± 0.66
Myelencephalon3.68 ± 0.56
Occipital Lobe3.8 ± 0.6
Parietal Lobe3.73 ± 0.51
Pontine Tegmentum3.65 ± 0.58
Striatum4.31 ± 0.45
Subthalamus3.73 ± 0.13
Temporal Lobe3.66 ± 0.54
Thalamus3.6 ± 0.66
White Matter3.16 ± 0.62
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ubqln4CBCerebellum27.17
34.81
Ubqln4CTXCerebral cortex96.12
81.12
Ubqln4HIPHippocampal region52.77
81.73
Ubqln4HPFHippocampal formation59.23
71.52
Ubqln4HYHypothalamus35.48
29.2
Ubqln4LSXLateral septal complex31.29
22.69
Ubqln4MBMidbrain43.23
41.65
Ubqln4MYMedulla44.55
54.07
Ubqln4OLFOlfactory bulb79.42
82.88
Ubqln4PPons40.49
45.98
Ubqln4PALPallidum44.64
47.05
Ubqln4RHPRetrohippocampal region69.64
60.75
Ubqln4sAMYStriatum-like amygdalar nuclei43.33
34.66
Ubqln4STRStriatum63.84
49.87
Ubqln4STRdStriatum dorsal region69.01
54.3
Ubqln4STRvStriatum ventral region71.68
54.58
Ubqln4THThalamus55.67
50.57
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009816 10 22 31 DKEEIVICDR Peptide Atlas
UBQL4_HUMAN_217 15 217 231 HMIMANPQMQQLMER PRIDE
UBQL4_HUMAN_559 16 559 574 FQQQLEQLNSMGFINR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018