AutismKB 2.0

Annotation Detail for DPYSL5


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Basic Information Top
Gene Symbol:DPYSL5 ( CRAM,CRMP-5,CRMP5,FLJ45383,Ulip6 )
Gene Full Name: dihydropyrimidinase-like 5
Band: 2p23.3
Quick LinksEntrez ID:56896; OMIM: 608383; Uniprot ID:DPYL5_HUMAN; ENSEMBL ID: ENSG00000157851; HGNC ID: 20637
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus90 / 564012159
neonate0 / 310970 
infant5 / 23620211
juvenile3 / 5555653
adult39 / 193912120
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor19 / 26384572
glioma12 / 106883112
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal182 / 336030754
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS13 / 125680103
prostate cancer0 / 1026800 
retinoblastoma15 / 46356323
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain177 / 1100989160
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye23 / 211054108
heart0 / 896260 
intestine1 / 2344724
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis15 / 33044245
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P210224
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.43 ± 0.63
Basal Forebrain10.93 ± 0.19
Basal Part of Pons10.24 ± 0.32
Cerebellar Cortex9.66 ± 0.11
Cerebellar Nuclei10.78 ± 0.43
Claustrum9.89 ± 0.48
Epithalamus9.18 ± 1.19
Frontal Lobe10.23 ± 0.52
Globus Pallidus10.85 ± 0.32
Hypothalamus10.55 ± 0.21
Insula10.15 ± 0.43
Limbic Lobe9.74 ± 0.62
Mesencephalon10.36 ± 0.56
Myelencephalon10.2 ± 0.64
Occipital Lobe9.59 ± 0.49
Parietal Lobe9.78 ± 0.45
Pontine Tegmentum10.18 ± 0.41
Striatum11.31 ± 0.38
Subthalamus10.33 ± 0.39
Temporal Lobe10.05 ± 0.43
Thalamus10.41 ± 0.4
White Matter12.59 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Dpysl5CBCerebellum0
0
Dpysl5CTXCerebral cortex0
0
Dpysl5HIPHippocampal region0
0
Dpysl5HPFHippocampal formation0
0
Dpysl5HYHypothalamus0
0
Dpysl5LSXLateral septal complex0
0
Dpysl5MBMidbrain21.14
20.09
Dpysl5MYMedulla0
0
Dpysl5OLFOlfactory bulb21.19
18.9
Dpysl5PPons0
0
Dpysl5PALPallidum0
0
Dpysl5RHPRetrohippocampal region0
0
Dpysl5sAMYStriatum-like amygdalar nuclei0
0
Dpysl5STRStriatum0
0
Dpysl5STRdStriatum dorsal region0
0
Dpysl5STRvStriatum ventral region0
0
Dpysl5THThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00064454 11 432 442 CHGVPLVTISR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018