AutismKB 2.0

Annotation Detail for WRNIP1


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Basic Information Top
Gene Symbol:WRNIP1 ( FLJ22526,RP11-420G6.2,WHIP,bA420G6.2 )
Gene Full Name: Werner helicase interacting protein 1
Band: 6p25.2
Quick LinksEntrez ID:56897; OMIM: 608196; Uniprot ID:WRIP1_HUMAN; ENSEMBL ID: ENSG00000124535; HGNC ID: 20876
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus49 / 56401286
neonate0 / 310970 
infant2 / 2362084
juvenile1 / 5555617
adult97 / 193912150
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor2 / 3436658
chondrosarcoma7 / 8282384
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor9 / 26384534
glioma13 / 106883121
head and neck tumor5 / 13630236
kidney tumor1 / 6895914
leukemia15 / 95842156
liver tumor6 / 9635962
lung tumor6 / 10312758
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal157 / 336030746
ovarian tumor8 / 76682104
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer3 / 10268029
retinoblastoma2 / 4635643
skin tumor3 / 12494924
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites3 / 4001574
bladder0 / 297570 
blood7 / 12347856
bone3 / 7165541
bone marrow1 / 4880120
brain45 / 110098940
cervix2 / 4817141
connective tissue3 / 14925520
ear2 / 16212123
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye9 / 21105442
heart3 / 8962633
intestine19 / 23447281
kidney10 / 21177747
larynx1 / 2414541
liver13 / 20774362
lung42 / 336974124
lymph1 / 4427022
lymph node11 / 91610120
mammary gland6 / 15327139
mouth0 / 670520 
muscle7 / 10771564
nerve1 / 1576863
ovary10 / 10205197
pancreas5 / 21481223
parathyroid8 / 20539389
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta8 / 28082528
prostate4 / 18934521
salivary gland0 / 201550 
skin10 / 21057447
spleen0 / 539520 
stomach6 / 9661962
testis8 / 33044224
thymus3 / 8113136
thyroid1 / 4747321
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11518_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.89 ± 0.45
Basal Forebrain5.22 ± 0.21
Basal Part of Pons5.16 ± 0.4
Cerebellar Cortex5.5 ± 0.26
Cerebellar Nuclei4.9 ± 0.46
Claustrum4.9 ± 0.65
Epithalamus5.24 ± 0.51
Frontal Lobe4.98 ± 0.44
Globus Pallidus5.14 ± 0.39
Hypothalamus5.17 ± 0.41
Insula5.14 ± 0.21
Limbic Lobe5.04 ± 0.49
Mesencephalon4.99 ± 0.48
Myelencephalon5.04 ± 0.43
Occipital Lobe5.1 ± 0.42
Parietal Lobe5.02 ± 0.38
Pontine Tegmentum5.02 ± 0.44
Striatum4.99 ± 0.47
Subthalamus4.63 ± 0.74
Temporal Lobe5.13 ± 0.4
Thalamus4.97 ± 0.35
White Matter5.77 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Wrnip1CBCerebellum6.6
9.32
Wrnip1CTXCerebral cortex60.96
51.76
Wrnip1HIPHippocampal region23.04
43.67
Wrnip1HPFHippocampal formation25.41
37.74
Wrnip1HYHypothalamus32.92
27.51
Wrnip1LSXLateral septal complex33.97
25.99
Wrnip1MBMidbrain18.66
19.57
Wrnip1MYMedulla13.55
16.68
Wrnip1OLFOlfactory bulb33.34
31.25
Wrnip1PPons18.02
21.85
Wrnip1PALPallidum15.32
13.68
Wrnip1RHPRetrohippocampal region30.48
31.05
Wrnip1sAMYStriatum-like amygdalar nuclei19.73
17.53
Wrnip1STRStriatum24.01
18.49
Wrnip1STRdStriatum dorsal region23.03
17.86
Wrnip1STRvStriatum ventral region23.85
15.65
Wrnip1THThalamus33.9
32.66
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009570 18 39 56 CLLLHPAGHAEPAAGSHR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018