AutismKB 2.0

Annotation Detail for ANKS1B


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Basic Information Top
Gene Symbol:ANKS1B ( AIDA,AIDA-1,ANKS2,EB-1,EB1,MGC26087,cajalin-2 )
Gene Full Name: ankyrin repeat and sterile alpha motif domain containing 1B
Band: 12q23.1
Quick LinksEntrez ID:56899; OMIM: 607815; Uniprot ID:ANS1B_HUMAN; ENSEMBL ID: ENSG00000185046; HGNC ID: 24600
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus48 / 56401285
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult54 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor7 / 68959101
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia12 / 97250123
normal255 / 336030775
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain282 / 1100989256
cervix0 / 481710 
connective tissue0 / 1492550 
ear3 / 16212185
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine0 / 2344720 
kidney7 / 21177733
larynx0 / 241450 
liver0 / 2077430 
lung8 / 33697423
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary0 / 1020510 
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis12 / 33044236
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219989_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.9
Adipocyte3.9
AdrenalCortex4.2
Adrenalgland3.3
Amygdala4.1
Appendix4
AtrioventricularNode3.05
BDCA4+_DentriticCells4.35
Bonemarrow3.85
BronchialEpithelialCells3.9
CD105+_Endothelial4
CD14+_Monocytes4.2
CD19+_BCells(neg._sel.)4.5
CD33+_Myeloid5.05
CD34+5
CD4+_Tcells4.3
CD56+_NKCells4.8
CD71+_EarlyErythroid3.7
CD8+_Tcells3.9
CardiacMyocytes5.15
Caudatenucleus3.5
Cerebellum3.15
CerebellumPeduncles4.5
CiliaryGanglion2.95
CingulateCortex4
Colorectaladenocarcinoma3.95
DorsalRootGanglion3.05
FetalThyroid3.8
Fetalbrain3.85
Fetalliver3.45
Fetallung3.2
GlobusPallidus2.9
Heart5.15
Hypothalamus4.25
Kidney3.15
Leukemia_chronicMyelogenousK-5623.55
Leukemia_promyelocytic-HL-603.5
Leukemialymphoblastic(MOLT-4)3.15
Liver5.25
Lung4.3
Lymphnode3.35
Lymphoma_burkitts(Daudi)5
Lymphoma_burkitts(Raji)5.6
MedullaOblongata3.55
OccipitalLobe3.55
OlfactoryBulb3.1
Ovary2.9
Pancreas3.15
PancreaticIslet4.2
ParietalLobe4.15
Pituitary4.6
Placenta4
Pons3.75
PrefrontalCortex4.9
Prostate4.6
Salivarygland3.2
SkeletalMuscle4.65
Skin3.05
SmoothMuscle4.5
Spinalcord4.2
SubthalamicNucleus3.65
SuperiorCervicalGanglion4.5
TemporalLobe3.65
Testis3.4
TestisGermCell3.3
TestisIntersitial3.4
TestisLeydigCell3.85
TestisSeminiferousTubule3.4
Thalamus4
Thymus3.1
Thyroid4.9
Tongue3.9
Tonsil3.8
Trachea3.3
TrigeminalGanglion4
Uterus3.2
UterusCorpus3.5
WholeBlood4.3
Wholebrain3.25
colon3.95
pineal_day4.96
pineal_night4.86
retina4.8
small_intestine3.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P21842
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.55 ± 0.24
Basal Forebrain7.26 ± 0.25
Basal Part of Pons7.1 ± 0.32
Cerebellar Cortex6.96 ± 0.18
Cerebellar Nuclei6.67 ± 0.3
Claustrum6.86 ± 0.21
Epithalamus6.95 ± 0.28
Frontal Lobe6.97 ± 0.32
Globus Pallidus6.57 ± 0.26
Hypothalamus6.83 ± 0.25
Insula7.22 ± 0.33
Limbic Lobe7.28 ± 0.48
Mesencephalon7.1 ± 0.51
Myelencephalon7.13 ± 0.4
Occipital Lobe7.77 ± 0.38
Parietal Lobe7.26 ± 0.25
Pontine Tegmentum7.11 ± 0.41
Striatum8.17 ± 0.3
Subthalamus6.8 ± 0.26
Temporal Lobe7.21 ± 0.25
Thalamus7.35 ± 0.4
White Matter7.94 ± 0.3
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Anks1bCBCerebellum100
100
Anks1bCTXCerebral cortex100
100
Anks1bHIPHippocampal region100
100
Anks1bHPFHippocampal formation100
100
Anks1bHYHypothalamus85.43
91.12
Anks1bLSXLateral septal complex100
100
Anks1bMBMidbrain85.62
100
Anks1bMYMedulla82.22
100
Anks1bOLFOlfactory bulb100
100
Anks1bPPons72.61
94.03
Anks1bPALPallidum93.5
100
Anks1bRHPRetrohippocampal region100
100
Anks1bsAMYStriatum-like amygdalar nuclei100
100
Anks1bSTRStriatum100
100
Anks1bSTRdStriatum dorsal region100
100
Anks1bSTRvStriatum ventral region100
100
Anks1bTHThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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