AutismKB 2.0

Annotation Detail for MEIS3


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Basic Information Top
Gene Symbol:MEIS3 ( DKFZp547H236,MRG2 )
Gene Full Name: Meis homeobox 3
Band: 19q13.32
Quick LinksEntrez ID:56917; OMIM: NA; Uniprot ID:MEIS3_HUMAN; ENSEMBL ID: ENSG00000105419; HGNC ID: 29537
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus11 / 56401219
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor20 / 119369167
germ cell tumor3 / 26384511
glioma9 / 10688384
head and neck tumor3 / 13630222
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal69 / 336030720
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS15 / 125680119
prostate cancer1 / 1026809
retinoblastoma2 / 4635643
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain42 / 110098938
cervix5 / 48171103
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye11 / 21105452
heart0 / 896260 
intestine5 / 23447221
kidney2 / 2117779
larynx3 / 24145124
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate1 / 1893455
salivary gland1 / 2015549
skin0 / 2105740 
spleen0 / 539520 
stomach19 / 96619196
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus13 / 23287855
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P78795
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.8 ± 0.57
Basal Forebrain3.78 ± 0.64
Basal Part of Pons3.25 ± 0.56
Cerebellar Cortex3.83 ± 0.78
Cerebellar Nuclei3.54 ± 0.46
Claustrum4.74 ± 0.65
Epithalamus3.31 ± 0.77
Frontal Lobe4.2 ± 0.75
Globus Pallidus2.47 ± 0.9
Hypothalamus3.36 ± 0.51
Insula4.36 ± 0.4
Limbic Lobe4.59 ± 0.64
Mesencephalon3.81 ± 0.89
Myelencephalon3.83 ± 0.77
Occipital Lobe3.35 ± 0.87
Parietal Lobe3.95 ± 0.79
Pontine Tegmentum4.01 ± 0.79
Striatum2.19 ± 1.18
Subthalamus3.61 ± 0.89
Temporal Lobe4.42 ± 0.54
Thalamus3.13 ± 0.77
White Matter2.06 ± 0.89
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mrg2CBCerebellum23.78
23.93
Mrg2CTXCerebral cortex44.66
20.81
Mrg2HIPHippocampal region28.84
25.22
Mrg2HPFHippocampal formation30.09
21.88
Mrg2HYHypothalamus19.15
9.62
Mrg2LSXLateral septal complex6.52
4.15
Mrg2MBMidbrain25.61
14.77
Mrg2MYMedulla41.41
31.9
Mrg2OLFOlfactory bulb41.64
25.32
Mrg2PPons24.66
13.58
Mrg2PALPallidum24.47
14.74
Mrg2RHPRetrohippocampal region32.91
18.01
Mrg2sAMYStriatum-like amygdalar nuclei25.71
12.46
Mrg2STRStriatum19.24
11.22
Mrg2STRdStriatum dorsal region13.65
8.53
Mrg2STRvStriatum ventral region38.45
20.65
Mrg2THThalamus19.82
10.84
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018