AutismKB 2.0

Annotation Detail for MRPS22


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Basic Information Top
Gene Symbol:MRPS22 ( C3orf5,COXPD5,GIBT,MRP-S22,RPMS22 )
Gene Full Name: mitochondrial ribosomal protein S22
Band: 3q23
Quick LinksEntrez ID:56945; OMIM: 605810; Uniprot ID:RT22_HUMAN; ENSEMBL ID: ENSG00000175110; HGNC ID: 14508
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219220_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts153.3
Adipocyte32.8
AdrenalCortex37.3
Adrenalgland41.7
Amygdala20
Appendix20.2
AtrioventricularNode17.7
BDCA4+_DentriticCells41.15
Bonemarrow13.15
BronchialEpithelialCells66.25
CD105+_Endothelial94.25
CD14+_Monocytes51.15
CD19+_BCells(neg._sel.)55.85
CD33+_Myeloid66.3
CD34+96.25
CD4+_Tcells38.6
CD56+_NKCells42.15
CD71+_EarlyErythroid47.55
CD8+_Tcells33.75
CardiacMyocytes30.35
Caudatenucleus22.3
Cerebellum11.75
CerebellumPeduncles25.25
CiliaryGanglion16.45
CingulateCortex27.35
Colorectaladenocarcinoma58
DorsalRootGanglion14.45
FetalThyroid41.2
Fetalbrain20.25
Fetalliver31.5
Fetallung27.25
GlobusPallidus28.35
Heart11.1
Hypothalamus36.05
Kidney19.15
Leukemia_chronicMyelogenousK-56285.55
Leukemia_promyelocytic-HL-6058.65
Leukemialymphoblastic(MOLT-4)37.1
Liver32.5
Lung15.4
Lymphnode21.95
Lymphoma_burkitts(Daudi)91.15
Lymphoma_burkitts(Raji)20.85
MedullaOblongata22.15
OccipitalLobe25.5
OlfactoryBulb19.8
Ovary14.5
Pancreas22.7
PancreaticIslet31.15
ParietalLobe28.55
Pituitary27.9
Placenta17.7
Pons19.3
PrefrontalCortex31.15
Prostate20.9
Salivarygland19.15
SkeletalMuscle27.7
Skin21.85
SmoothMuscle50.6
Spinalcord27.8
SubthalamicNucleus25.15
SuperiorCervicalGanglion22.3
TemporalLobe22.8
Testis32.25
TestisGermCell43.9
TestisIntersitial71.75
TestisLeydigCell35.1
TestisSeminiferousTubule39.75
Thalamus32.7
Thymus25.95
Thyroid21.1
Tongue27.8
Tonsil25.7
Trachea17
TrigeminalGanglion24.3
Uterus23.85
UterusCorpus18.25
WholeBlood31.1
Wholebrain28.4
colon27.7
pineal_day31.32
pineal_night27.96
retina16.375
small_intestine33.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8944_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.21 ± 0.7
Basal Forebrain4.31 ± 0.28
Basal Part of Pons4.68 ± 0.52
Cerebellar Cortex4.2 ± 0.5
Cerebellar Nuclei4.43 ± 0.76
Claustrum3.66 ± 0.94
Epithalamus4.04 ± 0.57
Frontal Lobe4.63 ± 0.46
Globus Pallidus4.47 ± 0.36
Hypothalamus4.48 ± 0.42
Insula4.43 ± 0.51
Limbic Lobe4.11 ± 0.69
Mesencephalon4.19 ± 0.64
Myelencephalon4.29 ± 0.6
Occipital Lobe3.69 ± 0.62
Parietal Lobe4.39 ± 0.55
Pontine Tegmentum4.3 ± 0.58
Striatum3.87 ± 0.54
Subthalamus4.99 ± 0.12
Temporal Lobe4.41 ± 0.47
Thalamus4.28 ± 0.5
White Matter4.39 ± 0.53
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003588 21 224 244 HVDVLNLCFAQFEPDSTEYIK Peptide Atlas
RT22_HUMAN_104 12 104 115 LMTQAQLEEATR PRIDE
RT22_HUMAN_117 9 117 125 QAVEAAKVR PRIDE
RT22_HUMAN_202 14 202 215 KILTPIIFKEENLR PRIDE
RT22_HUMAN_67 15 67 81 KPTFMDEEVQSILTK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018