AutismKB 2.0

Annotation Detail for SMYD2


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Basic Information Top
Gene Symbol:SMYD2 ( HSKM-B,KMT3C,MGC119305,ZMYND14 )
Gene Full Name: SET and MYND domain containing 2
Band: 1q32.3
Quick LinksEntrez ID:56950; OMIM: 610663; Uniprot ID:SMYD2_HUMAN; ENSEMBL ID: ENSG00000143499; HGNC ID: 20982
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus39 / 56401269
neonate2 / 3109764
infant0 / 236200 
juvenile3 / 5555653
adult118 / 193912160
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma6 / 8282372
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor3 / 26384511
glioma3 / 10688328
head and neck tumor2 / 13630214
kidney tumor6 / 6895987
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma4 / 7175555
non-neoplasia5 / 9725051
normal157 / 336030746
ovarian tumor1 / 7668213
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor22 / 125191175
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder2 / 2975767
blood4 / 12347832
bone3 / 7165541
bone marrow0 / 488010 
brain38 / 110098934
cervix3 / 4817162
connective tissue23 / 149255154
ear1 / 1621261
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye6 / 21105428
heart1 / 8962611
intestine8 / 23447234
kidney13 / 21177761
larynx0 / 241450 
liver6 / 20774328
lung17 / 33697450
lymph1 / 4427022
lymph node11 / 91610120
mammary gland3 / 15327119
mouth0 / 670520 
muscle5 / 10771546
nerve1 / 1576863
ovary1 / 1020519
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland4 / 16585241
placenta20 / 28082571
prostate7 / 18934536
salivary gland0 / 201550 
skin9 / 21057442
spleen0 / 539520 
stomach3 / 9661931
testis5 / 33044215
thymus0 / 811310 
thyroid3 / 4747363
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus14 / 23287860
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212922_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts240.15
Adipocyte71.35
AdrenalCortex50.55
Adrenalgland47.85
Amygdala207.5
Appendix45.05
AtrioventricularNode15.15
BDCA4+_DentriticCells137.9
Bonemarrow29.05
BronchialEpithelialCells384.45
CD105+_Endothelial34.3
CD14+_Monocytes63.45
CD19+_BCells(neg._sel.)245.6
CD33+_Myeloid100.65
CD34+139.2
CD4+_Tcells235.55
CD56+_NKCells205.95
CD71+_EarlyErythroid9.9
CD8+_Tcells198.7
CardiacMyocytes34.45
Caudatenucleus25.75
Cerebellum51.1
CerebellumPeduncles38.3
CiliaryGanglion19.5
CingulateCortex224.5
Colorectaladenocarcinoma208.95
DorsalRootGanglion28.1
FetalThyroid101.6
Fetalbrain111.75
Fetalliver43.65
Fetallung96
GlobusPallidus115.3
Heart236.85
Hypothalamus133.4
Kidney66.9
Leukemia_chronicMyelogenousK-562139.45
Leukemia_promyelocytic-HL-60160.75
Leukemialymphoblastic(MOLT-4)136.7
Liver45
Lung100.5
Lymphnode109.3
Lymphoma_burkitts(Daudi)230.05
Lymphoma_burkitts(Raji)70
MedullaOblongata181.65
OccipitalLobe204.15
OlfactoryBulb22.55
Ovary19.5
Pancreas69.55
PancreaticIslet67.4
ParietalLobe196.2
Pituitary207
Placenta120.55
Pons91
PrefrontalCortex327.25
Prostate121.15
Salivarygland65.8
SkeletalMuscle112.8
Skin16.25
SmoothMuscle174.9
Spinalcord67.45
SubthalamicNucleus190.15
SuperiorCervicalGanglion51.95
TemporalLobe259.7
Testis195.4
TestisGermCell321.5
TestisIntersitial178.45
TestisLeydigCell144
TestisSeminiferousTubule147.5
Thalamus64.75
Thymus75.3
Thyroid277.9
Tongue51.8
Tonsil86.85
Trachea64.2
TrigeminalGanglion20.55
Uterus38.7
UterusCorpus59.55
WholeBlood73.45
Wholebrain367.5
colon43.55
pineal_day36.38
pineal_night35.74
retina32.125
small_intestine39.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13761_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.18 ± 0.37
Basal Forebrain6.31 ± 0.51
Basal Part of Pons7.21 ± 0.33
Cerebellar Cortex6.43 ± 0.33
Cerebellar Nuclei7.64 ± 0.42
Claustrum6.67 ± 0.7
Epithalamus7.02 ± 0.32
Frontal Lobe7.31 ± 0.56
Globus Pallidus6.35 ± 0.86
Hypothalamus7.23 ± 0.63
Insula6.95 ± 0.3
Limbic Lobe6.86 ± 0.62
Mesencephalon6.61 ± 0.71
Myelencephalon6.77 ± 0.69
Occipital Lobe6.37 ± 0.85
Parietal Lobe7.29 ± 0.67
Pontine Tegmentum7.12 ± 0.62
Striatum5.6 ± 0.96
Subthalamus7.55 ± 0.29
Temporal Lobe7.16 ± 0.4
Thalamus6.47 ± 0.82
White Matter5.49 ± 0.79
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Smyd2CBCerebellum86.34
100
Smyd2CTXCerebral cortex100
100
Smyd2HIPHippocampal region100
100
Smyd2HPFHippocampal formation100
100
Smyd2HYHypothalamus100
100
Smyd2LSXLateral septal complex100
100
Smyd2MBMidbrain100
100
Smyd2MYMedulla100
100
Smyd2OLFOlfactory bulb100
100
Smyd2PPons100
100
Smyd2PALPallidum100
100
Smyd2RHPRetrohippocampal region100
100
Smyd2sAMYStriatum-like amygdalar nuclei100
100
Smyd2STRStriatum93.83
92.11
Smyd2STRdStriatum dorsal region78.26
73.52
Smyd2STRvStriatum ventral region100
91.44
Smyd2THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00065132 16 147 162 DLIQSDIAALHHFYSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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