Annotation Detail for ATXN7L3
Basic Information Top
| Gene Symbol: | ATXN7L3 ( DKFZp761G2113 ) |
|---|---|
| Gene Full Name: | ataxin 7-like 3 |
| Band: | 17q21.31 |
| Quick Links | Entrez ID:56970; OMIM: NA; Uniprot ID:AT7L3_HUMAN; ENSEMBL ID: ENSG00000087152; HGNC ID: 25416 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.512651
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 10 / 70761 | 141 |  |
| blastocyst | 4 / 62319 | 64 | |
| fetus | 31 / 564012 | 54 | |
| neonate | 0 / 31097 | 0 | |
| infant | 1 / 23620 | 42 |  |
| juvenile | 1 / 55556 | 17 | |
| adult | 93 / 1939121 | 47 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 5 / 82823 | 60 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 23 / 263845 | 87 | |
| glioma | 12 / 106883 | 112 | |
| head and neck tumor | 9 / 136302 | 66 | |
| kidney tumor | 4 / 68959 | 58 | |
| leukemia | 6 / 95842 | 62 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 8 / 71755 | 111 | |
| non-neoplasia | 4 / 97250 | 41 | |
| normal | 150 / 3360307 | 44 | |
| ovarian tumor | 5 / 76682 | 65 | |
| pancreatic tumor | 4 / 104616 | 38 | |
| primitive neuroectodermal tumor of the CNS | 3 / 125680 | 23 | |
| prostate cancer | 5 / 102680 | 48 | |
| retinoblastoma | 8 / 46356 | 172 | |
| skin tumor | 20 / 124949 | 160 | |
| soft tissue/muscle tissue tumor | 7 / 125191 | 55 | |
| uterine tumor | 3 / 90257 | 33 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 3 / 40015 | 74 | |
| bladder | 0 / 29757 | 0 | |
| blood | 6 / 123478 | 48 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 61 / 1100989 | 55 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 5 / 149255 | 33 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 17 / 215722 | 78 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 12 / 211054 | 56 | |
| heart | 9 / 89626 | 100 | |
| intestine | 6 / 234472 | 25 | |
| kidney | 5 / 211777 | 23 | |
| larynx | 2 / 24145 | 82 | |
| liver | 0 / 207743 | 0 | |
| lung | 6 / 336974 | 17 | |
| lymph | 6 / 44270 | 135 | |
| lymph node | 2 / 91610 | 21 | |
| mammary gland | 8 / 153271 | 52 | |
| mouth | 6 / 67052 | 89 | |
| muscle | 1 / 107715 | 9 |  |
| nerve | 1 / 15768 | 63 | |
| ovary | 7 / 102051 | 68 | |
| pancreas | 4 / 214812 | 18 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 15 / 280825 | 53 | |
| prostate | 6 / 189345 | 31 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 23 / 210574 | 109 | |
| spleen | 3 / 53952 | 55 | |
| stomach | 0 / 96619 | 0 | |
| testis | 19 / 330442 | 57 | |
| thymus | 12 / 81131 | 147 | |
| thyroid | 4 / 47473 | 84 | |
| tonsil | 1 / 16999 | 58 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 2 / 13680 | 146 | |
| uterus | 16 / 232878 | 68 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: A_23_P421935
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 6.11 ± 0.4 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 5.84 ± 0.26 | |
| Basal Part of Pons | 6.59 ± 0.2 | |
| Cerebellar Cortex | 5.9 ± 0.27 | |
| Cerebellar Nuclei | 5.92 ± 0.3 | |
| Claustrum | 6.06 ± 0.38 | |
| Epithalamus | 5.58 ± 0.22 | |
| Frontal Lobe | 6.27 ± 0.38 | |
| Globus Pallidus | 5.44 ± 0.39 | |
| Hypothalamus | 5.53 ± 0.25 | |
| Insula | 6.26 ± 0.25 | |
| Limbic Lobe | 6.17 ± 0.37 | |
| Mesencephalon | 5.88 ± 0.41 | |
| Myelencephalon | 6.07 ± 0.45 | |
| Occipital Lobe | 5.86 ± 0.5 | |
| Parietal Lobe | 6.22 ± 0.37 | |
| Pontine Tegmentum | 5.94 ± 0.38 | |
| Striatum | 5.68 ± 0.56 | |
| Subthalamus | 6 ± 0.15 | |
| Temporal Lobe | 6.27 ± 0.29 | |
| Thalamus | 6.16 ± 0.29 | |
| White Matter | 4.98 ± 0.31 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Atxn7l3 | CB | Cerebellum | 40.29 | |
| 83.11 | | |||
| Atxn7l3 | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Atxn7l3 | HIP | Hippocampal region | 100 | |
| 100 | | |||
| Atxn7l3 | HPF | Hippocampal formation | 100 | |
| 100 | | |||
| Atxn7l3 | HY | Hypothalamus | 75.31 | |
| 74.31 | | |||
| Atxn7l3 | LSX | Lateral septal complex | 78.64 | |
| 68.93 | | |||
| Atxn7l3 | MB | Midbrain | 100 | |
| 100 | | |||
| Atxn7l3 | MY | Medulla | 90.33 | |
| 100 | | |||
| Atxn7l3 | OLF | Olfactory bulb | 100 | |
| 100 | | |||
| Atxn7l3 | P | Pons | 87.63 | |
| 100 | | |||
| Atxn7l3 | PAL | Pallidum | 89.79 | |
| 100 | | |||
| Atxn7l3 | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Atxn7l3 | sAMY | Striatum-like amygdalar nuclei | 95.39 | |
| 90.88 | | |||
| Atxn7l3 | STR | Striatum | 90.32 | |
| 81.62 | | |||
| Atxn7l3 | STRd | Striatum dorsal region | 90.62 | |
| 82.96 | | |||
| Atxn7l3 | STRv | Striatum ventral region | 96.31 | |
| 82.67 | | |||
| Atxn7l3 | TH | Thalamus | 100 | |
| 100 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00011489 | 15 | 203 | 217 | SLLTTQCGVISEHTK | Peptide Atlas |