AutismKB 2.0

Annotation Detail for TULP4


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Basic Information Top
Gene Symbol:TULP4 ( KIAA1397,TUSP )
Gene Full Name: tubby like protein 4
Band: 6q25.3
Quick LinksEntrez ID:56995; OMIM: NA; Uniprot ID:TULP4_HUMAN; ENSEMBL ID: ENSG00000130338; HGNC ID: 15530
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus27 / 56401247
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult74 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor2 / 3436658
chondrosarcoma5 / 8282360
colorectal tumor10 / 11424687
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor16 / 26384560
glioma2 / 10688318
head and neck tumor7 / 13630251
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal113 / 336030733
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer6 / 10268058
retinoblastoma2 / 4635643
skin tumor1 / 1249498
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood1 / 1234788
bone3 / 7165541
bone marrow0 / 488010 
brain36 / 110098932
cervix2 / 4817141
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye14 / 21105466
heart1 / 8962611
intestine11 / 23447246
kidney5 / 21177723
larynx4 / 24145165
liver1 / 2077434
lung7 / 33697420
lymph0 / 442700 
lymph node3 / 9161032
mammary gland7 / 15327145
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas3 / 21481213
parathyroid1 / 2053948
pharynx3 / 4132872
pituitary gland0 / 165850 
placenta7 / 28082524
prostate7 / 18934536
salivary gland1 / 2015549
skin17 / 21057480
spleen2 / 5395237
stomach3 / 9661931
testis16 / 33044248
thymus1 / 8113112
thyroid2 / 4747342
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218184_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.85
Adipocyte4.95
AdrenalCortex5.25
Adrenalgland4.35
Amygdala9.55
Appendix5.1
AtrioventricularNode3.8
BDCA4+_DentriticCells7.6
Bonemarrow4.95
BronchialEpithelialCells4.9
CD105+_Endothelial4.95
CD14+_Monocytes5.4
CD19+_BCells(neg._sel.)12.4
CD33+_Myeloid6.9
CD34+6.3
CD4+_Tcells5.85
CD56+_NKCells8.55
CD71+_EarlyErythroid4.75
CD8+_Tcells6.85
CardiacMyocytes6.45
Caudatenucleus10.5
Cerebellum6.4
CerebellumPeduncles18.3
CiliaryGanglion3.55
CingulateCortex21.65
Colorectaladenocarcinoma4.95
DorsalRootGanglion3.85
FetalThyroid5.1
Fetalbrain16.85
Fetalliver4.25
Fetallung3.95
GlobusPallidus5.65
Heart6.3
Hypothalamus17.85
Kidney4.15
Leukemia_chronicMyelogenousK-5624.6
Leukemia_promyelocytic-HL-604.5
Leukemialymphoblastic(MOLT-4)3.9
Liver6.45
Lung5.45
Lymphnode4.25
Lymphoma_burkitts(Daudi)6.7
Lymphoma_burkitts(Raji)6.95
MedullaOblongata24.7
OccipitalLobe23.4
OlfactoryBulb4.45
Ovary3.4
Pancreas4.75
PancreaticIslet5.5
ParietalLobe17.05
Pituitary18.45
Placenta6.8
Pons19
PrefrontalCortex42.7
Prostate5.75
Salivarygland4.2
SkeletalMuscle6.45
Skin4
SmoothMuscle6.05
Spinalcord9.2
SubthalamicNucleus14.7
SuperiorCervicalGanglion5.75
TemporalLobe17.35
Testis4.35
TestisGermCell5.25
TestisIntersitial4.25
TestisLeydigCell5.15
TestisSeminiferousTubule4.7
Thalamus16.15
Thymus4.1
Thyroid6.5
Tongue5
Tonsil5.1
Trachea4.35
TrigeminalGanglion5.3
Uterus4.2
UterusCorpus4.8
WholeBlood5.5
Wholebrain15.6
colon5
pineal_day105.34
pineal_night114.08
retina10.85
small_intestine4.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P382045
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.76 ± 0.43
Basal Forebrain9.12 ± 0.19
Basal Part of Pons8.53 ± 0.2
Cerebellar Cortex8.76 ± 0.29
Cerebellar Nuclei9.27 ± 0.18
Claustrum9.11 ± 0.3
Epithalamus8.56 ± 0.53
Frontal Lobe8.95 ± 0.3
Globus Pallidus9.66 ± 0.27
Hypothalamus9.16 ± 0.24
Insula8.84 ± 0.27
Limbic Lobe8.64 ± 0.38
Mesencephalon9.09 ± 0.35
Myelencephalon8.91 ± 0.43
Occipital Lobe8.72 ± 0.5
Parietal Lobe9.15 ± 0.28
Pontine Tegmentum9.11 ± 0.26
Striatum8.95 ± 0.28
Subthalamus9.58 ± 0.19
Temporal Lobe8.87 ± 0.3
Thalamus8.89 ± 0.37
White Matter10.15 ± 0.35
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Tulp4CBCerebellum89.34
57.36
Tulp4CTXCerebral cortex47.16
22.8
Tulp4HIPHippocampal region64.68
35.17
Tulp4HPFHippocampal formation70.7
37.5
Tulp4HYHypothalamus70.88
46.95
Tulp4LSXLateral septal complex59.42
26.44
Tulp4MBMidbrain75.34
45.31
Tulp4MYMedulla86.45
72.78
Tulp4OLFOlfactory bulb71.07
41.11
Tulp4PPons78.69
57.98
Tulp4PALPallidum63.32
36.18
Tulp4RHPRetrohippocampal region83.22
41.76
Tulp4sAMYStriatum-like amygdalar nuclei62.49
37.18
Tulp4STRStriatum33.35
16.41
Tulp4STRdStriatum dorsal region24.73
13.14
Tulp4STRvStriatum ventral region23.3
9.8
Tulp4THThalamus45.43
23.3
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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