AutismKB 2.0

Annotation Detail for CCNL1


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Basic Information Top
Gene Symbol:CCNL1 ( ANIA6A,PRO1073,ania-6a )
Gene Full Name: cyclin L1
Band: 3q25.31
Quick LinksEntrez ID:57018; OMIM: 613384; Uniprot ID:CCNL1_HUMAN; ENSEMBL ID: ENSG00000163660; HGNC ID: 20569
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body9 / 70761127
blastocyst6 / 6231996
fetus47 / 56401283
neonate2 / 3109764
infant2 / 2362084
juvenile4 / 5555671
adult230 / 1939121118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor1 / 3436629
chondrosarcoma11 / 82823132
colorectal tumor11 / 11424696
esophageal tumor5 / 17290289
gastrointestinal tumor11 / 11936992
germ cell tumor17 / 26384564
glioma1 / 1068839
head and neck tumor14 / 136302102
kidney tumor2 / 6895929
leukemia30 / 95842313
liver tumor2 / 9635920
lung tumor4 / 10312738
lymphoma3 / 7175541
non-neoplasia15 / 97250154
normal367 / 3360307109
ovarian tumor14 / 76682182
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer12 / 102680116
retinoblastoma1 / 4635621
skin tumor6 / 12494948
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor12 / 90257132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites2 / 4001549
bladder5 / 29757168
blood33 / 123478267
bone6 / 7165583
bone marrow11 / 48801225
brain78 / 110098970
cervix2 / 4817141
connective tissue19 / 149255127
ear0 / 162120 
embryonic tissue22 / 215722101
esophagus5 / 20209247
eye19 / 21105490
heart3 / 8962633
intestine21 / 23447289
kidney14 / 21177766
larynx2 / 2414582
liver12 / 20774357
lung46 / 336974136
lymph3 / 4427067
lymph node17 / 91610185
mammary gland10 / 15327165
mouth7 / 67052104
muscle11 / 107715102
nerve3 / 15768190
ovary17 / 102051166
pancreas15 / 21481269
parathyroid0 / 205390 
pharynx5 / 41328120
pituitary gland3 / 16585180
placenta24 / 28082585
prostate20 / 189345105
salivary gland0 / 201550 
skin16 / 21057475
spleen13 / 53952240
stomach9 / 9661993
testis25 / 33044275
thymus30 / 81131369
thyroid1 / 4747321
tonsil0 / 169990 
trachea12 / 52413228
umbilical cord0 / 136800 
uterus39 / 232878167
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220046_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts311.7
Adipocyte26.35
AdrenalCortex196.6
Adrenalgland22.15
Amygdala28.55
Appendix32.1
AtrioventricularNode19.6
BDCA4+_DentriticCells1586
Bonemarrow18.35
BronchialEpithelialCells26.55
CD105+_Endothelial410
CD14+_Monocytes667.85
CD19+_BCells(neg._sel.)875.65
CD33+_Myeloid3874.3
CD34+1163.6
CD4+_Tcells1928.05
CD56+_NKCells923.25
CD71+_EarlyErythroid221.35
CD8+_Tcells1847
CardiacMyocytes16.95
Caudatenucleus24.55
Cerebellum11.9
CerebellumPeduncles14.2
CiliaryGanglion64.35
CingulateCortex25.5
Colorectaladenocarcinoma135.65
DorsalRootGanglion20.05
FetalThyroid59.15
Fetalbrain28.1
Fetalliver30.25
Fetallung233.25
GlobusPallidus15.95
Heart11.1
Hypothalamus74.8
Kidney9.2
Leukemia_chronicMyelogenousK-56258.25
Leukemia_promyelocytic-HL-6086.75
Leukemialymphoblastic(MOLT-4)154.65
Liver11.1
Lung15.15
Lymphnode329.85
Lymphoma_burkitts(Daudi)181.7
Lymphoma_burkitts(Raji)37.25
MedullaOblongata24.6
OccipitalLobe24.1
OlfactoryBulb85.2
Ovary82.2
Pancreas82.55
PancreaticIslet48
ParietalLobe23.25
Pituitary82.55
Placenta29.35
Pons17.95
PrefrontalCortex43.45
Prostate31.8
Salivarygland91.4
SkeletalMuscle10.75
Skin69.15
SmoothMuscle30.45
Spinalcord42.7
SubthalamicNucleus14.55
SuperiorCervicalGanglion27.15
TemporalLobe6.95
Testis6.2
TestisGermCell77.8
TestisIntersitial29.05
TestisLeydigCell26.05
TestisSeminiferousTubule23.1
Thalamus35.25
Thymus33.45
Thyroid66.85
Tongue29.1
Tonsil147.1
Trachea41.95
TrigeminalGanglion17.85
Uterus134.8
UterusCorpus36.3
WholeBlood123.8
Wholebrain15.8
colon49.7
pineal_day120.1
pineal_night104.54
retina61
small_intestine25.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P337058
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.44 ± 0.22
Basal Forebrain7.52 ± 0.16
Basal Part of Pons7.34 ± 0.25
Cerebellar Cortex7.73 ± 0.16
Cerebellar Nuclei7.56 ± 0.24
Claustrum7.43 ± 0.36
Epithalamus7.63 ± 0.23
Frontal Lobe7.27 ± 0.3
Globus Pallidus7.91 ± 0.32
Hypothalamus7.12 ± 0.34
Insula7.26 ± 0.27
Limbic Lobe7.54 ± 0.45
Mesencephalon7.44 ± 0.32
Myelencephalon7.45 ± 0.32
Occipital Lobe7.87 ± 0.45
Parietal Lobe7.47 ± 0.31
Pontine Tegmentum7.45 ± 0.5
Striatum7.74 ± 0.5
Subthalamus7.24 ± 0.25
Temporal Lobe7.36 ± 0.32
Thalamus7.45 ± 0.27
White Matter8.72 ± 0.17
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ccnl1CBCerebellum0
0
Ccnl1CTXCerebral cortex0
0
Ccnl1HIPHippocampal region0
0
Ccnl1HPFHippocampal formation0
0
Ccnl1HYHypothalamus0
0
Ccnl1LSXLateral septal complex0
0
Ccnl1MBMidbrain0
0
Ccnl1MYMedulla0
0
Ccnl1OLFOlfactory bulb0
0
Ccnl1PPons0
0
Ccnl1PALPallidum0
0
Ccnl1RHPRetrohippocampal region0
0
Ccnl1sAMYStriatum-like amygdalar nuclei0
0
Ccnl1STRStriatum0
0
Ccnl1STRdStriatum dorsal region0
0
Ccnl1STRvStriatum ventral region0
0
Ccnl1THThalamus0
0
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
CCNL1_HUMAN_36 10 36 45 TTGGILIGDR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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