Annotation Detail for PDXP
Basic Information Top
| Gene Symbol: | PDXP ( CIN,FLJ32703,PLP,dJ37E16.5 ) |
|---|---|
| Gene Full Name: | pyridoxal (pyridoxine, vitamin B6) phosphatase |
| Band: | 22q13.1 |
| Quick Links | Entrez ID:57026; OMIM: 609246; Uniprot ID:PLPP_HUMAN; ENSEMBL ID: ENSG00000100092; HGNC ID: 30259 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.632762
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 44 / 564012 | 78 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 3 / 55556 | 53 | |
| adult | 64 / 1939121 | 33 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 2 / 263845 | 7 |  |
| glioma | 7 / 106883 | 65 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 18 / 95842 | 187 | |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 4 / 103127 | 38 | |
| lymphoma | 7 / 71755 | 97 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 115 / 3360307 | 34 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 48 / 125680 | 381 |  |
| prostate cancer | 5 / 102680 | 48 | |
| retinoblastoma | 9 / 46356 | 194 | |
| skin tumor | 9 / 124949 | 72 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 4 / 40015 | 99 | |
| bladder | 0 / 29757 | 0 | |
| blood | 16 / 123478 | 129 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 71 / 1100989 | 64 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 3 / 215722 | 13 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 14 / 211054 | 66 | |
| heart | 11 / 89626 | 122 | |
| intestine | 3 / 234472 | 12 | |
| kidney | 1 / 211777 | 4 | |
| larynx | 0 / 24145 | 0 | |
| liver | 3 / 207743 | 14 | |
| lung | 8 / 336974 | 23 | |
| lymph | 3 / 44270 | 67 | |
| lymph node | 2 / 91610 | 21 | |
| mammary gland | 2 / 153271 | 13 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 6 / 214812 | 27 | |
| parathyroid | 2 / 20539 | 97 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 9 / 280825 | 32 | |
| prostate | 6 / 189345 | 31 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 9 / 210574 | 42 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 7 / 330442 | 21 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 1 / 16999 | 58 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 2 / 232878 | 8 | |
| vascular | 1 / 51780 | 19 | |
Microarray in - Probe name: CUST_12622_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.24 ± 0.42 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.81 ± 0.48 | |
| Basal Part of Pons | 5.39 ± 0.53 | |
| Cerebellar Cortex | 5.11 ± 0.59 | |
| Cerebellar Nuclei | 4.7 ± 0.48 | |
| Claustrum | 5 ± 0.5 | |
| Epithalamus | 4.26 ± 0.75 | |
| Frontal Lobe | 5.29 ± 0.56 | |
| Globus Pallidus | 4.26 ± 0.51 | |
| Hypothalamus | 4.85 ± 0.58 | |
| Insula | 5.38 ± 0.25 | |
| Limbic Lobe | 5.23 ± 0.54 | |
| Mesencephalon | 4.96 ± 0.6 | |
| Myelencephalon | 5.1 ± 0.62 | |
| Occipital Lobe | 4.44 ± 0.54 | |
| Parietal Lobe | 5.12 ± 0.54 | |
| Pontine Tegmentum | 4.86 ± 0.58 | |
| Striatum | 4.5 ± 0.52 | |
| Subthalamus | 4.81 ± 0.54 | |
| Temporal Lobe | 5.32 ± 0.46 | |
| Thalamus | 4.92 ± 0.55 | |
| White Matter | 3.61 ± 0.67 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Pdxp | CB | Cerebellum | 55.89 | |
| 87.87 | | |||
| Pdxp | CTX | Cerebral cortex | 100 | |
| 100 | | |||
| Pdxp | HIP | Hippocampal region | 100 | |
| 100 | | |||
| Pdxp | HPF | Hippocampal formation | 100 | |
| 100 | | |||
| Pdxp | HY | Hypothalamus | 74.17 | |
| 72.37 | | |||
| Pdxp | LSX | Lateral septal complex | 99.48 | |
| 97.69 | | |||
| Pdxp | MB | Midbrain | 74.13 | |
| 78.97 | | |||
| Pdxp | MY | Medulla | 49.46 | |
| 59.41 | | |||
| Pdxp | OLF | Olfactory bulb | 100 | |
| 100 | | |||
| Pdxp | P | Pons | 39.41 | |
| 48.63 | | |||
| Pdxp | PAL | Pallidum | 82.73 | |
| 96.13 | | |||
| Pdxp | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Pdxp | sAMY | Striatum-like amygdalar nuclei | 100 | |
| 100 | | |||
| Pdxp | STR | Striatum | 100 | |
| 97.28 | | |||
| Pdxp | STRd | Striatum dorsal region | 100 | |
| 92.45 | | |||
| Pdxp | STRv | Striatum ventral region | 100 | |
| 89.86 | | |||
| Pdxp | TH | Thalamus | 96.06 | |
| 100 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00072412 | 14 | 129 | 142 | LAGDPSAGDGAAPR | Peptide Atlas |
| PLPP_HUMAN_250 | 14 | 250 | 263 | CGMTTVLTLTGVSR | PRIDE |