AutismKB 2.0

Annotation Detail for RARS2


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Basic Information Top
Gene Symbol:RARS2 ( ArgRS,DALRD2,MGC14993,MGC23778,PCH6,PRO1992,RARSL,dJ382I10.6 )
Gene Full Name: arginyl-tRNA synthetase 2, mitochondrial
Band: 6q15
Quick LinksEntrez ID:57038; OMIM: 611524; Uniprot ID:SYRM_HUMAN; ENSEMBL ID: ENSG00000146282; HGNC ID: 21406
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus43 / 56401276
neonate4 / 31097128
infant7 / 23620296
juvenile8 / 55556143
adult95 / 193912148
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma2 / 17475114
breast (mammary gland) tumor2 / 9417821
cervical tumor5 / 34366145
chondrosarcoma7 / 8282384
colorectal tumor3 / 11424626
esophageal tumor2 / 17290115
gastrointestinal tumor5 / 11936941
germ cell tumor26 / 26384598
glioma1 / 1068839
head and neck tumor5 / 13630236
kidney tumor2 / 6895929
leukemia10 / 95842104
liver tumor6 / 9635962
lung tumor11 / 103127106
lymphoma0 / 717550 
non-neoplasia11 / 97250113
normal213 / 336030763
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS14 / 125680111
prostate cancer2 / 10268019
retinoblastoma6 / 46356129
skin tumor6 / 12494948
soft tissue/muscle tissue tumor11 / 12519187
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland4 / 33197120
ascites0 / 400150 
bladder5 / 29757168
blood8 / 12347864
bone5 / 7165569
bone marrow7 / 48801143
brain50 / 110098945
cervix8 / 48171166
connective tissue9 / 14925560
ear0 / 162120 
embryonic tissue17 / 21572278
esophagus2 / 2020998
eye12 / 21105456
heart11 / 89626122
intestine11 / 23447246
kidney7 / 21177733
larynx0 / 241450 
liver16 / 20774377
lung19 / 33697456
lymph0 / 442700 
lymph node2 / 9161021
mammary gland3 / 15327119
mouth1 / 6705214
muscle6 / 10771555
nerve1 / 1576863
ovary4 / 10205139
pancreas4 / 21481218
parathyroid1 / 2053948
pharynx5 / 41328120
pituitary gland0 / 165850 
placenta27 / 28082596
prostate7 / 18934536
salivary gland4 / 20155198
skin17 / 21057480
spleen3 / 5395255
stomach8 / 9661982
testis41 / 330442124
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord2 / 13680146
uterus21 / 23287890
vascular8 / 51780154
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_7818_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.95 ± 0.43
Basal Forebrain7.31 ± 0.1
Basal Part of Pons7.48 ± 0.18
Cerebellar Cortex7.62 ± 0.19
Cerebellar Nuclei7.58 ± 0.18
Claustrum6.78 ± 0.42
Epithalamus7.26 ± 0.3
Frontal Lobe7.4 ± 0.28
Globus Pallidus7.4 ± 0.24
Hypothalamus7.45 ± 0.26
Insula7.35 ± 0.28
Limbic Lobe7.21 ± 0.31
Mesencephalon7.27 ± 0.35
Myelencephalon7.25 ± 0.32
Occipital Lobe7.09 ± 0.37
Parietal Lobe7.22 ± 0.32
Pontine Tegmentum7.32 ± 0.36
Striatum7.22 ± 0.28
Subthalamus7.33 ± 0.08
Temporal Lobe7.31 ± 0.28
Thalamus7.38 ± 0.2
White Matter8.02 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
RarslCBCerebellum12.2
14.24
RarslCTXCerebral cortex31.02
21.49
RarslHIPHippocampal region28.33
29.46
RarslHPFHippocampal formation30.15
27.93
RarslHYHypothalamus12.3
8.39
RarslLSXLateral septal complex8.05
5.36
RarslMBMidbrain8.84
7.86
RarslMYMedulla8.81
10.29
RarslOLFOlfactory bulb31.02
24.25
RarslPPons12.57
13.24
RarslPALPallidum13.95
11.54
RarslRHPRetrohippocampal region35.1
27.23
RarslsAMYStriatum-like amygdalar nuclei12.28
9.23
RarslSTRStriatum13.81
9.56
RarslSTRdStriatum dorsal region13.67
9.22
RarslSTRvStriatum ventral region18.45
12.78
RarslTHThalamus14.29
10.95
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00503370 21 16 36 VLNLPPENLITSISAVPISQK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018