Annotation Detail for CASC5
Basic Information Top
| Gene Symbol: | CASC5 ( AF15Q14,CT29,D40,KIAA1570,KNL1,hKNL-1,hSpc105 ) |
|---|---|
| Gene Full Name: | cancer susceptibility candidate 5 |
| Band: | 15q14 |
| Quick Links | Entrez ID:57082; OMIM: 609173; Uniprot ID:CASC5_HUMAN; ENSEMBL ID: ENSG00000137812; HGNC ID: |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.181855
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 2 / 62319 | 32 | |
| fetus | 4 / 564012 | 7 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 15 / 1939121 | 7 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 |  |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 2 / 114246 | 17 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 2 / 95842 | 20 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 39 / 3360307 | 11 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 4 / 104616 | 38 | |
| primitive neuroectodermal tumor of the CNS | 1 / 125680 | 7 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 2 / 124949 | 16 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 2 / 123478 | 16 | |
| bone | 3 / 71655 | 41 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 4 / 1100989 | 3 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 5 / 215722 | 23 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 3 / 234472 | 12 | |
| kidney | 4 / 211777 | 18 | |
| larynx | 0 / 24145 | 0 | |
| liver | 10 / 207743 | 48 | |
| lung | 3 / 336974 | 8 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 8 / 91610 | 87 | |
| mammary gland | 2 / 153271 | 13 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 4 / 107715 | 37 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 4 / 214812 | 18 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 2 / 20155 | 99 | |
| skin | 2 / 210574 | 9 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 10 / 330442 | 30 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: A_23_P100127
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 2.1 ± 0.99 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.63 ± 0.29 | |
| Basal Part of Pons | 1.32 ± 0.39 | |
| Cerebellar Cortex | 1.58 ± 0.71 | |
| Cerebellar Nuclei | 2.03 ± 0.82 | |
| Claustrum | 2.51 ± 0.86 | |
| Epithalamus | 1.39 ± 0.69 | |
| Frontal Lobe | 1.57 ± 0.64 | |
| Globus Pallidus | 2.31 ± 0.46 | |
| Hypothalamus | 1.75 ± 0.53 | |
| Insula | 1.78 ± 0.54 | |
| Limbic Lobe | 1.74 ± 0.62 | |
| Mesencephalon | 1.89 ± 0.64 | |
| Myelencephalon | 1.79 ± 0.63 | |
| Occipital Lobe | 1.83 ± 0.59 | |
| Parietal Lobe | 1.71 ± 0.68 | |
| Pontine Tegmentum | 1.74 ± 0.65 | |
| Striatum | 1.97 ± 0.48 | |
| Subthalamus | 1.93 ± 0.71 | |
| Temporal Lobe | 1.61 ± 0.65 | |
| Thalamus | 1.73 ± 0.64 | |
| White Matter | 2.01 ± 0.22 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Casc5 | CB | Cerebellum | 0.29 | |
| 0.59 | | |||
| Casc5 | CTX | Cerebral cortex | 0.18 | |
| 0.26 | | |||
| Casc5 | HIP | Hippocampal region | 0.17 | |
| 0.18 | | |||
| Casc5 | HPF | Hippocampal formation | 0.22 | |
| 0.36 | | |||
| Casc5 | HY | Hypothalamus | 0.08 | |
| 0.07 | | |||
| Casc5 | LSX | Lateral septal complex | 0.11 | |
| 0.05 | | |||
| Casc5 | MB | Midbrain | 0.11 | |
| 0.14 | | |||
| Casc5 | MY | Medulla | 0.24 | |
| 0.32 | | |||
| Casc5 | OLF | Olfactory bulb | 0.12 | |
| 0.11 | | |||
| Casc5 | P | Pons | 0.22 | |
| 0.34 | | |||
| Casc5 | PAL | Pallidum | 0.14 | |
| 0.16 | | |||
| Casc5 | RHP | Retrohippocampal region | 0.26 | |
| 0.61 | | |||
| Casc5 | sAMY | Striatum-like amygdalar nuclei | 0.05 | |
| 0.02 | | |||
| Casc5 | STR | Striatum | 0.15 | |
| 0.21 | | |||
| Casc5 | STRd | Striatum dorsal region | 0.15 | |
| 0.27 | | |||
| Casc5 | STRv | Striatum ventral region | 0.15 | |
| 0.13 | | |||
| Casc5 | TH | Thalamus | 0.16 | |
| 0.7 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| CASC5_HUMAN_912 | 6 | 912 | 917 | PLLEKR | PRIDE |
| PAp00011457 | 20 | 414 | 433 | SHIMGAETHIVSQTCNQDAR | Peptide Atlas |