AutismKB 2.0

Annotation Detail for PLSCR4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:PLSCR4 ( TRA1 )
Gene Full Name: phospholipid scramblase 4
Band: 3q24
Quick LinksEntrez ID:57088; OMIM: 607612; Uniprot ID:PLS4_HUMAN; ENSEMBL ID: ENSG00000114698; HGNC ID: 16497
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus10 / 56401217
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult35 / 193912118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor6 / 26384522
glioma3 / 10688328
head and neck tumor7 / 13630251
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal87 / 336030725
ovarian tumor3 / 7668239
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland3 / 3319790
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow1 / 4880120
brain35 / 110098931
cervix1 / 4817120
connective tissue3 / 14925520
ear3 / 16212185
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye4 / 21105418
heart1 / 8962611
intestine3 / 23447212
kidney4 / 21177718
larynx3 / 24145124
liver4 / 20774319
lung8 / 33697423
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth2 / 6705229
muscle2 / 10771518
nerve1 / 1576863
ovary3 / 10205129
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta11 / 28082539
prostate2 / 18934510
salivary gland0 / 201550 
skin3 / 21057414
spleen1 / 5395218
stomach0 / 966190 
testis29 / 33044287
thymus9 / 81131110
thyroid2 / 4747342
tonsil0 / 169990 
trachea7 / 52413133
umbilical cord0 / 136800 
uterus1 / 2328784
vascular5 / 5178096
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218901_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.05
Adipocyte46.1
AdrenalCortex43.3
Adrenalgland45.95
Amygdala56.05
Appendix48.3
AtrioventricularNode33.1
BDCA4+_DentriticCells5.35
Bonemarrow5.35
BronchialEpithelialCells4.8
CD105+_Endothelial7.95
CD14+_Monocytes5.85
CD19+_BCells(neg._sel.)5.2
CD33+_Myeloid6.2
CD34+7.25
CD4+_Tcells5.65
CD56+_NKCells5.7
CD71+_EarlyErythroid7.1
CD8+_Tcells4.75
CardiacMyocytes36.7
Caudatenucleus6.25
Cerebellum10.25
CerebellumPeduncles7.75
CiliaryGanglion6.35
CingulateCortex5.8
Colorectaladenocarcinoma5.15
DorsalRootGanglion39
FetalThyroid7.4
Fetalbrain5.25
Fetalliver21.75
Fetallung33.6
GlobusPallidus5.1
Heart7.25
Hypothalamus39.7
Kidney6.6
Leukemia_chronicMyelogenousK-5624.6
Leukemia_promyelocytic-HL-604.55
Leukemialymphoblastic(MOLT-4)3.8
Liver7.15
Lung8
Lymphnode14.7
Lymphoma_burkitts(Daudi)6.85
Lymphoma_burkitts(Raji)7.55
MedullaOblongata5.2
OccipitalLobe6.55
OlfactoryBulb79.95
Ovary5.55
Pancreas5.6
PancreaticIslet8.3
ParietalLobe6.3
Pituitary10.4
Placenta29.75
Pons5.65
PrefrontalCortex50.3
Prostate7.75
Salivarygland21.1
SkeletalMuscle6.75
Skin7.75
SmoothMuscle139.2
Spinalcord121.75
SubthalamicNucleus5.2
SuperiorCervicalGanglion12.55
TemporalLobe7
Testis11.1
TestisGermCell72.55
TestisIntersitial29.05
TestisLeydigCell20.1
TestisSeminiferousTubule6.25
Thalamus6.85
Thymus5.05
Thyroid119.1
Tongue5.9
Tonsil5.35
Trachea31.1
TrigeminalGanglion12.9
Uterus78.25
UterusCorpus6.1
WholeBlood5.45
Wholebrain12.7
colon106.95
pineal_day49.78
pineal_night49.58
retina158.575
small_intestine75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P91910
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.63 ± 0.64
Basal Forebrain7 ± 0.31
Basal Part of Pons5.28 ± 0.59
Cerebellar Cortex6.07 ± 0.41
Cerebellar Nuclei5.77 ± 0.66
Claustrum5.92 ± 0.62
Epithalamus7.75 ± 0.35
Frontal Lobe6.41 ± 0.59
Globus Pallidus8.01 ± 0.5
Hypothalamus7.09 ± 0.31
Insula6.52 ± 0.54
Limbic Lobe6.44 ± 0.86
Mesencephalon6.72 ± 0.6
Myelencephalon6.64 ± 0.7
Occipital Lobe6.66 ± 0.69
Parietal Lobe6.48 ± 0.66
Pontine Tegmentum6.65 ± 0.47
Striatum6.66 ± 0.48
Subthalamus6.04 ± 0.49
Temporal Lobe6.26 ± 0.5
Thalamus6.71 ± 0.51
White Matter5.22 ± 0.88
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved