AutismKB 2.0

Annotation Detail for INTS12


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Basic Information Top
Gene Symbol:INTS12 ( INT12,PHF22 )
Gene Full Name: integrator complex subunit 12
Band: 4q24
Quick LinksEntrez ID:57117; OMIM: 611355; Uniprot ID:INT12_HUMAN; ENSEMBL ID: ENSG00000138785; HGNC ID: 25067
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus29 / 56401251
neonate0 / 310970 
infant2 / 2362084
juvenile1 / 5555617
adult47 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma7 / 8282384
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor3 / 26384511
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia5 / 9584252
liver tumor4 / 9635941
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia3 / 9725030
normal108 / 336030732
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer1 / 1026809
retinoblastoma1 / 4635621
skin tumor5 / 12494940
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites1 / 4001524
bladder0 / 297570 
blood3 / 12347824
bone1 / 7165513
bone marrow4 / 4880181
brain19 / 110098917
cervix1 / 4817120
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye11 / 21105452
heart0 / 896260 
intestine2 / 2344728
kidney7 / 21177733
larynx0 / 241450 
liver6 / 20774328
lung14 / 33697441
lymph0 / 442700 
lymph node6 / 9161065
mammary gland1 / 1532716
mouth0 / 670520 
muscle3 / 10771527
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid2 / 2053997
pharynx5 / 41328120
pituitary gland1 / 1658560
placenta7 / 28082524
prostate3 / 18934515
salivary gland0 / 201550 
skin8 / 21057437
spleen0 / 539520 
stomach0 / 966190 
testis7 / 33044221
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218616_at
Cell line Expression level Expression bar
721_B_lymphoblasts79.2
Adipocyte9.3
AdrenalCortex8.65
Adrenalgland7.4
Amygdala8.8
Appendix8.35
AtrioventricularNode8.15
BDCA4+_DentriticCells131.8
Bonemarrow9.8
BronchialEpithelialCells14.85
CD105+_Endothelial36.85
CD14+_Monocytes27.3
CD19+_BCells(neg._sel.)48.9
CD33+_Myeloid26.95
CD34+36.05
CD4+_Tcells22.8
CD56+_NKCells33.75
CD71+_EarlyErythroid29.1
CD8+_Tcells27.9
CardiacMyocytes14.25
Caudatenucleus8.05
Cerebellum8.05
CerebellumPeduncles11.4
CiliaryGanglion6.45
CingulateCortex9.25
Colorectaladenocarcinoma8.25
DorsalRootGanglion7.15
FetalThyroid8.85
Fetalbrain17
Fetalliver8.7
Fetallung7.55
GlobusPallidus7.1
Heart11.65
Hypothalamus12.95
Kidney7.7
Leukemia_chronicMyelogenousK-5629.3
Leukemia_promyelocytic-HL-6010.55
Leukemialymphoblastic(MOLT-4)23.4
Liver14.45
Lung9.25
Lymphnode10.05
Lymphoma_burkitts(Daudi)42.45
Lymphoma_burkitts(Raji)15.1
MedullaOblongata8.75
OccipitalLobe8.25
OlfactoryBulb7.6
Ovary6.3
Pancreas7.75
PancreaticIslet13.55
ParietalLobe10.1
Pituitary11.2
Placenta8.1
Pons8.05
PrefrontalCortex11.3
Prostate11.2
Salivarygland8.35
SkeletalMuscle10.85
Skin8.6
SmoothMuscle18.4
Spinalcord10.3
SubthalamicNucleus7.65
SuperiorCervicalGanglion10.4
TemporalLobe8.35
Testis8.2
TestisGermCell8
TestisIntersitial8.35
TestisLeydigCell10.25
TestisSeminiferousTubule9.5
Thalamus10.3
Thymus7.4
Thyroid15.9
Tongue9.3
Tonsil10.5
Trachea7.7
TrigeminalGanglion9.7
Uterus8.5
UterusCorpus8.25
WholeBlood16.35
Wholebrain7.55
colon12.2
pineal_day19.28
pineal_night13.54
retina11.8
small_intestine15.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8620_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.94 ± 0.26
Basal Forebrain6.3 ± 0.2
Basal Part of Pons5.72 ± 0.32
Cerebellar Cortex6.1 ± 0.41
Cerebellar Nuclei5.91 ± 0.36
Claustrum5.91 ± 0.46
Epithalamus6.09 ± 0.17
Frontal Lobe6.01 ± 0.33
Globus Pallidus6.42 ± 0.27
Hypothalamus6.45 ± 0.32
Insula5.99 ± 0.46
Limbic Lobe5.86 ± 0.37
Mesencephalon6.08 ± 0.39
Myelencephalon5.94 ± 0.39
Occipital Lobe5.88 ± 0.46
Parietal Lobe5.92 ± 0.32
Pontine Tegmentum6.04 ± 0.46
Striatum5.91 ± 0.31
Subthalamus6.08 ± 0.32
Temporal Lobe5.96 ± 0.34
Thalamus6.09 ± 0.31
White Matter6.46 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ints12STRdStriatum dorsal region4.54
5.09
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00079369 20 223 242 TQKPPQKPAPAVVSVTPAVK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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