Annotation Detail for SMURF1
Basic Information Top
| Gene Symbol: | SMURF1 ( KIAA1625 ) |
|---|---|
| Gene Full Name: | SMAD specific E3 ubiquitin protein ligase 1 |
| Band: | 7q22.1 |
| Quick Links | Entrez ID:57154; OMIM: 605568; Uniprot ID:SMUF1_HUMAN; ENSEMBL ID: ENSG00000198742; HGNC ID: 16807 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.189329
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 5 / 62319 | 80 |  |
| fetus | 19 / 564012 | 33 | |
| neonate | 1 / 31097 | 32 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 3 / 55556 | 53 | |
| adult | 85 / 1939121 | 43 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 6 / 114246 | 52 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 9 / 119369 | 75 | |
| germ cell tumor | 20 / 263845 | 75 | |
| glioma | 9 / 106883 | 84 | |
| head and neck tumor | 4 / 136302 | 29 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 7 / 95842 | 73 | |
| liver tumor | 2 / 96359 | 20 | |
| lung tumor | 9 / 103127 | 87 | |
| lymphoma | 3 / 71755 | 41 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 110 / 3360307 | 32 | |
| ovarian tumor | 6 / 76682 | 78 | |
| pancreatic tumor | 6 / 104616 | 57 | |
| primitive neuroectodermal tumor of the CNS | 3 / 125680 | 23 | |
| prostate cancer | 1 / 102680 | 9 |  |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 7 / 124949 | 56 | |
| soft tissue/muscle tissue tumor | 1 / 125191 | 7 | |
| uterine tumor | 4 / 90257 | 44 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 1 / 29757 | 33 | |
| blood | 5 / 123478 | 40 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 1 / 48801 | 20 | |
| brain | 30 / 1100989 | 27 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 1 / 16212 | 61 | |
| embryonic tissue | 11 / 215722 | 50 | |
| esophagus | 1 / 20209 | 49 | |
| eye | 8 / 211054 | 37 | |
| heart | 2 / 89626 | 22 | |
| intestine | 9 / 234472 | 38 | |
| kidney | 8 / 211777 | 37 | |
| larynx | 1 / 24145 | 41 | |
| liver | 4 / 207743 | 19 | |
| lung | 12 / 336974 | 35 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 6 / 91610 | 65 | |
| mammary gland | 7 / 153271 | 45 | |
| mouth | 3 / 67052 | 44 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 5 / 102051 | 48 | |
| pancreas | 10 / 214812 | 46 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 8 / 280825 | 28 | |
| prostate | 3 / 189345 | 15 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 13 / 210574 | 61 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 7 / 96619 | 72 | |
| testis | 34 / 330442 | 102 | |
| thymus | 2 / 81131 | 24 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 4 / 52413 | 76 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 7 / 232878 | 30 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 212666_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 12.1 | |
| Adipocyte | 9.9 | |
| AdrenalCortex | 11.25 | |
| Adrenalgland | 15.7 | |
| Amygdala | 12.05 | |
| Appendix | 14.6 | |
| AtrioventricularNode | 8.9 | |
| BDCA4+_DentriticCells | 11 | |
| Bonemarrow | 10.6 | |
| BronchialEpithelialCells | 29.75 | |
| CD105+_Endothelial | 9.75 | |
| CD14+_Monocytes | 11.2 | |
| CD19+_BCells(neg._sel.) | 11.05 | |
| CD33+_Myeloid | 13.65 | |
| CD34+ | 12.8 | |
| CD4+_Tcells | 11.15 | |
| CD56+_NKCells | 11.1 | |
| CD71+_EarlyErythroid | 9.85 | |
| CD8+_Tcells | 10.45 | |
| CardiacMyocytes | 14.25 | |
| Caudatenucleus | 9.75 | |
| Cerebellum | 9.65 | |
| CerebellumPeduncles | 12.95 | |
| CiliaryGanglion | 7.95 | |
| CingulateCortex | 11 | |
| Colorectaladenocarcinoma | 11.3 | |
| DorsalRootGanglion | 8.5 | |
| FetalThyroid | 10.35 | |
| Fetalbrain | 13.75 | |
| Fetalliver | 9.15 | |
| Fetallung | 9.3 | |
| GlobusPallidus | 8 | |
| Heart | 13.85 | |
| Hypothalamus | 11.65 | |
| Kidney | 8.8 | |
| Leukemia_chronicMyelogenousK-562 | 9.8 | |
| Leukemia_promyelocytic-HL-60 | 9.45 | |
| Leukemialymphoblastic(MOLT-4) | 8.5 | |
| Liver | 14.3 | |
| Lung | 23.2 | |
| Lymphnode | 8.85 | |
| Lymphoma_burkitts(Daudi) | 13.55 | |
| Lymphoma_burkitts(Raji) | 15.65 | |
| MedullaOblongata | 11.4 | |
| OccipitalLobe | 9.65 | |
| OlfactoryBulb | 8.3 | |
| Ovary | 7.3 | |
| Pancreas | 8.75 | |
| PancreaticIslet | 11.3 | |
| ParietalLobe | 11.55 | |
| Pituitary | 12.45 | |
| Placenta | 30.3 | |
| Pons | 10.45 | |
| PrefrontalCortex | 14.7 | |
| Prostate | 12.5 | |
| Salivarygland | 9.6 | |
| SkeletalMuscle | 14.1 | |
| Skin | 9.15 | |
| SmoothMuscle | 12.2 | |
| Spinalcord | 11.4 | |
| SubthalamicNucleus | 9.6 | |
| SuperiorCervicalGanglion | 13.9 | |
| TemporalLobe | 10 | |
| Testis | 123.4 | |
| TestisGermCell | 11.6 | |
| TestisIntersitial | 10.25 | |
| TestisLeydigCell | 11.65 | |
| TestisSeminiferousTubule | 16.05 | |
| Thalamus | 10.9 | |
| Thymus | 8.35 | |
| Thyroid | 13.45 | |
| Tongue | 11 | |
| Tonsil | 10.4 | |
| Trachea | 10.45 | |
| TrigeminalGanglion | 11.2 | |
| Uterus | 8.65 | |
| UterusCorpus | 10.05 | |
| WholeBlood | 11.7 | |
| Wholebrain | 21.5 | |
| colon | 10.6 | |
| pineal_day | 13.2 | |
| pineal_night | 13.92 | |
| retina | 16.175 | |
| small_intestine | 10.4 | |
- Probe name: A_23_P398254
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 6.05 ± 0.26 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.21 ± 0.32 | |
| Basal Part of Pons | 5.71 ± 0.29 | |
| Cerebellar Cortex | 5.61 ± 0.24 | |
| Cerebellar Nuclei | 6.07 ± 0.31 | |
| Claustrum | 6.17 ± 0.39 | |
| Epithalamus | 5.48 ± 0.36 | |
| Frontal Lobe | 5.96 ± 0.36 | |
| Globus Pallidus | 6.08 ± 0.24 | |
| Hypothalamus | 5.87 ± 0.47 | |
| Insula | 5.76 ± 0.28 | |
| Limbic Lobe | 6.06 ± 0.35 | |
| Mesencephalon | 6.06 ± 0.37 | |
| Myelencephalon | 5.96 ± 0.41 | |
| Occipital Lobe | 6.19 ± 0.51 | |
| Parietal Lobe | 6.03 ± 0.32 | |
| Pontine Tegmentum | 6.01 ± 0.41 | |
| Striatum | 6.29 ± 0.36 | |
| Subthalamus | 6.06 ± 0.24 | |
| Temporal Lobe | 5.86 ± 0.3 | |
| Thalamus | 5.79 ± 0.43 | |
| White Matter | 6.69 ± 0.38 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Smurf1 | CB | Cerebellum | 25.73 | |
| 29.21 | | |||
| Smurf1 | CTX | Cerebral cortex | 100 | |
| 91.48 | | |||
| Smurf1 | HIP | Hippocampal region | 67.53 | |
| 96.84 | | |||
| Smurf1 | HPF | Hippocampal formation | 81.76 | |
| 100 | | |||
| Smurf1 | HY | Hypothalamus | 97.59 | |
| 92.14 | | |||
| Smurf1 | LSX | Lateral septal complex | 47.33 | |
| 34.85 | | |||
| Smurf1 | MB | Midbrain | 64.9 | |
| 60.08 | | |||
| Smurf1 | MY | Medulla | 92.05 | |
| 100 | | |||
| Smurf1 | OLF | Olfactory bulb | 80.69 | |
| 69.59 | | |||
| Smurf1 | P | Pons | 90.58 | |
| 100 | | |||
| Smurf1 | PAL | Pallidum | 76.23 | |
| 74.81 | | |||
| Smurf1 | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Smurf1 | sAMY | Striatum-like amygdalar nuclei | 84.44 | |
| 67.45 | | |||
| Smurf1 | STR | Striatum | 100 | |
| 82.6 | | |||
| Smurf1 | STRd | Striatum dorsal region | 100 | |
| 81.62 | | |||
| Smurf1 | STRv | Striatum ventral region | 100 | |
| 100 | | |||
| Smurf1 | TH | Thalamus | 76.66 | |
| 69.68 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00028982 | 7 | 722 | 728 | AHTCFNR | Peptide Atlas |