AutismKB 2.0

Annotation Detail for ACTR3B


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Basic Information Top
Gene Symbol:ACTR3B ( ARP11,ARP3BETA,DKFZp686O24114 )
Gene Full Name: ARP3 actin-related protein 3 homolog B (yeast)
Band: 7q36.1-q36.2
Quick LinksEntrez ID:57180; OMIM: NA; Uniprot ID:ARP3B_HUMAN; ENSEMBL ID: ENSG00000133627; HGNC ID: 17256
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus14 / 56401224
neonate0 / 310970 
infant1 / 2362042
juvenile2 / 5555635
adult54 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor30 / 119369251
germ cell tumor9 / 26384534
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia6 / 9584262
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal84 / 336030724
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS17 / 125680135
prostate cancer0 / 1026800 
retinoblastoma2 / 4635643
skin tumor4 / 12494932
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites30 / 40015749
bladder0 / 297570 
blood7 / 12347856
bone2 / 7165527
bone marrow0 / 488010 
brain54 / 110098949
cervix8 / 48171166
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye8 / 21105437
heart3 / 8962633
intestine1 / 2344724
kidney1 / 2117774
larynx1 / 2414541
liver1 / 2077434
lung3 / 3369748
lymph1 / 4427022
lymph node0 / 916100 
mammary gland6 / 15327139
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary5 / 10205148
pancreas2 / 2148129
parathyroid4 / 20539194
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta3 / 28082510
prostate0 / 1893450 
salivary gland0 / 201550 
skin4 / 21057418
spleen1 / 5395218
stomach0 / 966190 
testis8 / 33044224
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218868_at
Cell line Expression level Expression bar
721_B_lymphoblasts11.25
Adipocyte8.75
AdrenalCortex11.05
Adrenalgland7.8
Amygdala335.6
Appendix10.85
AtrioventricularNode8.55
BDCA4+_DentriticCells9.2
Bonemarrow9.7
BronchialEpithelialCells8.3
CD105+_Endothelial11.45
CD14+_Monocytes9.6
CD19+_BCells(neg._sel.)10.1
CD33+_Myeloid12.85
CD34+12.05
CD4+_Tcells9.85
CD56+_NKCells10.1
CD71+_EarlyErythroid8.6
CD8+_Tcells8.55
CardiacMyocytes14.55
Caudatenucleus68.5
Cerebellum7.55
CerebellumPeduncles11.65
CiliaryGanglion9.05
CingulateCortex14.45
Colorectaladenocarcinoma9.35
DorsalRootGanglion7.9
FetalThyroid8.7
Fetalbrain71.4
Fetalliver7.6
Fetallung6.15
GlobusPallidus16.5
Heart13.7
Hypothalamus20.2
Kidney7.55
Leukemia_chronicMyelogenousK-5628.2
Leukemia_promyelocytic-HL-608.2
Leukemialymphoblastic(MOLT-4)7.2
Liver12.3
Lung9.5
Lymphnode7.2
Lymphoma_burkitts(Daudi)11.8
Lymphoma_burkitts(Raji)14
MedullaOblongata9.7
OccipitalLobe21.1
OlfactoryBulb7.1
Ovary6.4
Pancreas7.4
PancreaticIslet9.85
ParietalLobe12.6
Pituitary10.85
Placenta8.65
Pons9.15
PrefrontalCortex36.45
Prostate9.95
Salivarygland7.8
SkeletalMuscle13.25
Skin8.1
SmoothMuscle9.65
Spinalcord9.6
SubthalamicNucleus8.7
SuperiorCervicalGanglion12.4
TemporalLobe12.7
Testis7.9
TestisGermCell7.9
TestisIntersitial7.8
TestisLeydigCell9.4
TestisSeminiferousTubule7.95
Thalamus9.55
Thymus6.65
Thyroid10.9
Tongue9.65
Tonsil9.05
Trachea7.35
TrigeminalGanglion10.55
Uterus7.15
UterusCorpus8.85
WholeBlood9.55
Wholebrain195.65
colon8.95
pineal_day12.98
pineal_night26.48
retina11.225
small_intestine8.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_3290_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.95 ± 0.35
Basal Forebrain6.36 ± 0.45
Basal Part of Pons6.99 ± 0.43
Cerebellar Cortex6.29 ± 0.13
Cerebellar Nuclei6.14 ± 0.72
Claustrum7.21 ± 0.34
Epithalamus6.11 ± 0.57
Frontal Lobe6.76 ± 0.42
Globus Pallidus5.66 ± 0.66
Hypothalamus6.19 ± 0.29
Insula6.74 ± 0.21
Limbic Lobe7.05 ± 0.54
Mesencephalon6.31 ± 0.53
Myelencephalon6.55 ± 0.59
Occipital Lobe6.42 ± 0.54
Parietal Lobe6.61 ± 0.41
Pontine Tegmentum6.55 ± 0.58
Striatum7.66 ± 0.43
Subthalamus6.47 ± 0.59
Temporal Lobe6.75 ± 0.37
Thalamus6.37 ± 0.37
White Matter4.8 ± 0.4
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00009856 23 169 191 DSGDGVTHVIPVAEGYVIGSCIK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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