AutismKB 2.0

Annotation Detail for RALGAPA2


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Basic Information Top
Gene Symbol:RALGAPA2 ( AS250,C20orf74,FLJ12819,KIAA1272,bA287B20.1,dJ1049G11,dJ1049G11.4 )
Gene Full Name: Ral GTPase activating protein, alpha subunit 2 (catalytic)
Band: 20p11.23
Quick LinksEntrez ID:57186; OMIM: NA; Uniprot ID:RGPA2_HUMAN; ENSEMBL ID: ENSG00000188559; HGNC ID: 16207
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus26 / 56401246
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult65 / 193912133
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor2 / 2638457
glioma0 / 1068830 
head and neck tumor6 / 13630244
kidney tumor1 / 6895914
leukemia8 / 9584283
liver tumor1 / 9635910
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia1 / 9725010
normal76 / 336030722
ovarian tumor0 / 766820 
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood9 / 12347872
bone2 / 7165527
bone marrow0 / 488010 
brain10 / 11009899
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine9 / 23447238
kidney2 / 2117779
larynx1 / 2414541
liver3 / 20774314
lung8 / 33697423
lymph0 / 442700 
lymph node4 / 9161043
mammary gland3 / 15327119
mouth0 / 670520 
muscle5 / 10771546
nerve0 / 157680 
ovary0 / 1020510 
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta10 / 28082535
prostate4 / 18934521
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach4 / 9661941
testis5 / 33044215
thymus2 / 8113124
thyroid3 / 4747363
tonsil0 / 169990 
trachea3 / 5241357
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_532_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.42 ± 0.49
Basal Forebrain5.87 ± 0.28
Basal Part of Pons5.29 ± 0.45
Cerebellar Cortex6.06 ± 0.16
Cerebellar Nuclei5.68 ± 0.33
Claustrum5.38 ± 0.6
Epithalamus5.66 ± 0.47
Frontal Lobe5.56 ± 0.4
Globus Pallidus5.84 ± 0.43
Hypothalamus5.29 ± 0.52
Insula5.5 ± 0.36
Limbic Lobe5.51 ± 0.46
Mesencephalon5.63 ± 0.5
Myelencephalon5.58 ± 0.45
Occipital Lobe6.1 ± 0.5
Parietal Lobe5.65 ± 0.42
Pontine Tegmentum5.76 ± 0.45
Striatum5.69 ± 0.45
Subthalamus5.56 ± 0.15
Temporal Lobe5.53 ± 0.38
Thalamus6.03 ± 0.42
White Matter6.68 ± 0.2
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
A230067G21RikCBCerebellum26.08
32.9
A230067G21RikCTXCerebral cortex45.11
32.93
A230067G21RikHIPHippocampal region54.09
77.23
A230067G21RikHPFHippocampal formation47.99
56.3
A230067G21RikHYHypothalamus14.33
9.16
A230067G21RikLSXLateral septal complex9.3
5.33
A230067G21RikMBMidbrain29.51
22.61
A230067G21RikMYMedulla38.24
33.97
A230067G21RikOLFOlfactory bulb54.39
47.52
A230067G21RikPPons31.43
28.02
A230067G21RikPALPallidum30.85
24.2
A230067G21RikRHPRetrohippocampal region36.01
26.08
A230067G21RiksAMYStriatum-like amygdalar nuclei21.54
14.11
A230067G21RikSTRStriatum25.66
17.87
A230067G21RikSTRdStriatum dorsal region21.98
16.22
A230067G21RikSTRvStriatum ventral region40.75
25.09
A230067G21RikTHThalamus20.64
17.15
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018