AutismKB 2.0

Annotation Detail for ATP10A


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Basic Information Top
Gene Symbol:ATP10A ( ATP10C,ATPVA,ATPVC,KIAA0566 )
Gene Full Name: ATPase, class V, type 10A
Band: 15q12
Quick LinksEntrez ID:57194; OMIM: 605855; Uniprot ID:AT10A_HUMAN; ENSEMBL ID: ENSG00000206190; HGNC ID: 13542
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult18 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor3 / 26384511
glioma3 / 10688328
head and neck tumor0 / 1363020 
kidney tumor2 / 6895929
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal24 / 33603077
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone3 / 7165541
bone marrow0 / 488010 
brain6 / 11009895
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin6 / 21057428
spleen0 / 539520 
stomach1 / 9661910
testis2 / 3304426
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214255_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.25
Adipocyte5.55
AdrenalCortex9.4
Adrenalgland7.25
Amygdala5.6
Appendix6.15
AtrioventricularNode6.1
BDCA4+_DentriticCells15.9
Bonemarrow5.45
BronchialEpithelialCells5.3
CD105+_Endothelial5.6
CD14+_Monocytes6.1
CD19+_BCells(neg._sel.)5.65
CD33+_Myeloid7.25
CD34+7.15
CD4+_Tcells16.65
CD56+_NKCells22.9
CD71+_EarlyErythroid5.2
CD8+_Tcells15.6
CardiacMyocytes7.05
Caudatenucleus5.05
Cerebellum4.55
CerebellumPeduncles6.7
CiliaryGanglion5.7
CingulateCortex5.9
Colorectaladenocarcinoma5.55
DorsalRootGanglion4.7
FetalThyroid5.25
Fetalbrain5.45
Fetalliver4.85
Fetallung4.25
GlobusPallidus4.75
Heart7.45
Hypothalamus6.4
Kidney4.5
Leukemia_chronicMyelogenousK-5624.95
Leukemia_promyelocytic-HL-604.8
Leukemialymphoblastic(MOLT-4)4.3
Liver7.35
Lung7.15
Lymphnode4.65
Lymphoma_burkitts(Daudi)6.9
Lymphoma_burkitts(Raji)7.65
MedullaOblongata5.05
OccipitalLobe5.05
OlfactoryBulb5.6
Ovary3.65
Pancreas4.75
PancreaticIslet5.8
ParietalLobe6.3
Pituitary6.5
Placenta5.65
Pons5.5
PrefrontalCortex9.95
Prostate6.15
Salivarygland5.45
SkeletalMuscle6.3
Skin4.7
SmoothMuscle6.3
Spinalcord5.95
SubthalamicNucleus5.45
SuperiorCervicalGanglion6.45
TemporalLobe5.25
Testis4.75
TestisGermCell4.5
TestisIntersitial4.5
TestisLeydigCell5.45
TestisSeminiferousTubule4.8
Thalamus5.8
Thymus4.15
Thyroid6.7
Tongue6.2
Tonsil5.5
Trachea4.7
TrigeminalGanglion5.95
Uterus4.5
UterusCorpus5.25
WholeBlood6.4
Wholebrain4.8
colon5.6
pineal_day8.1
pineal_night9.7
retina6.65
small_intestine5.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P65659
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.63 ± 0.69
Basal Forebrain2.2 ± 0.52
Basal Part of Pons2.44 ± 0.69
Cerebellar Cortex2.39 ± 0.71
Cerebellar Nuclei3.16 ± 0.59
Claustrum3.16 ± 0.81
Epithalamus2.37 ± 0.77
Frontal Lobe2.7 ± 0.7
Globus Pallidus3.25 ± 0.67
Hypothalamus2.29 ± 0.52
Insula2.49 ± 0.78
Limbic Lobe2.69 ± 0.61
Mesencephalon2.68 ± 0.73
Myelencephalon2.85 ± 0.71
Occipital Lobe3.12 ± 0.74
Parietal Lobe2.8 ± 0.67
Pontine Tegmentum2.94 ± 0.72
Striatum3.19 ± 0.6
Subthalamus4.37 ± 1.16
Temporal Lobe2.68 ± 0.68
Thalamus3.26 ± 0.68
White Matter2.82 ± 0.85
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Atp10aCBCerebellum1.35
2.05
Atp10aCTXCerebral cortex2.3
1.87
Atp10aHIPHippocampal region0.64
0.78
Atp10aHPFHippocampal formation4.95
4.18
Atp10aHYHypothalamus0.45
0.49
Atp10aLSXLateral septal complex0.89
0.57
Atp10aMBMidbrain0.7
0.78
Atp10aMYMedulla2.8
2.73
Atp10aOLFOlfactory bulb10.07
8.24
Atp10aPPons2.58
2.33
Atp10aPALPallidum0.68
0.84
Atp10aRHPRetrohippocampal region11.9
8.76
Atp10asAMYStriatum-like amygdalar nuclei1.62
0.96
Atp10aSTRStriatum1.2
0.88
Atp10aSTRdStriatum dorsal region1.39
1.1
Atp10aSTRvStriatum ventral region0.48
0.35
Atp10aTHThalamus7.69
5.4
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
AT10A_HUMAN_453 8 453 460 ANAQRLAR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018