Annotation Detail for PSME2
Basic Information Top
| Gene Symbol: | PSME2 ( PA28B,PA28beta,REGbeta ) |
|---|---|
| Gene Full Name: | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) |
| Band: | 14q12 |
| Quick Links | Entrez ID:5721; OMIM: 602161; Uniprot ID:PSME2_HUMAN; ENSEMBL ID: ENSG00000100911; HGNC ID: 9569 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.512410
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 5 / 70761 | 70 |  |
| blastocyst | 2 / 62319 | 32 |  |
| fetus | 62 / 564012 | 109 | |
| neonate | 1 / 31097 | 32 | |
| infant | 1 / 23620 | 42 | |
| juvenile | 3 / 55556 | 53 | |
| adult | 161 / 1939121 | 83 | |
| embryoid body | 2 / 70761 | 28 | |
| blastocyst | 2 / 62319 | 32 | |
| fetus | 0 / 564012 | 0 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 30 / 1939121 | 15 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 3 / 17475 | 171 | |
| breast (mammary gland) tumor | 17 / 94178 | 180 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 10 / 82823 | 120 | |
| colorectal tumor | 14 / 114246 | 122 | |
| esophageal tumor | 3 / 17290 | 173 | |
| gastrointestinal tumor | 9 / 119369 | 75 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 8 / 106883 | 74 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 6 / 68959 | 87 | |
| leukemia | 9 / 95842 | 93 | |
| liver tumor | 15 / 96359 | 155 | |
| lung tumor | 6 / 103127 | 58 | |
| lymphoma | 11 / 71755 | 153 | |
| non-neoplasia | 5 / 97250 | 51 | |
| normal | 275 / 3360307 | 81 | |
| ovarian tumor | 8 / 76682 | 104 | |
| pancreatic tumor | 14 / 104616 | 133 | |
| primitive neuroectodermal tumor of the CNS | 4 / 125680 | 31 | |
| prostate cancer | 8 / 102680 | 77 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 3 / 124949 | 24 | |
| soft tissue/muscle tissue tumor | 8 / 125191 | 63 | |
| uterine tumor | 23 / 90257 | 254 |  |
| adrenal tumor | 1 / 12794 | 78 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 6 / 94178 | 63 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 4 / 114246 | 35 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 6 / 263845 | 22 | |
| glioma | 1 / 106883 | 9 |  |
| head and neck tumor | 1 / 136302 | 7 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 9 / 96359 | 93 | |
| lung tumor | 4 / 103127 | 38 | |
| lymphoma | 6 / 71755 | 83 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 54 / 3360307 | 16 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 2 / 102680 | 19 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 3 / 124949 | 24 | |
| soft tissue/muscle tissue tumor | 9 / 125191 | 71 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 6 / 40015 | 149 | |
| bladder | 3 / 29757 | 100 | |
| blood | 19 / 123478 | 153 | |
| bone | 7 / 71655 | 97 | |
| bone marrow | 8 / 48801 | 163 | |
| brain | 47 / 1100989 | 42 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 6 / 149255 | 40 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 8 / 215722 | 37 | |
| esophagus | 3 / 20209 | 148 | |
| eye | 13 / 211054 | 61 | |
| heart | 5 / 89626 | 55 | |
| intestine | 22 / 234472 | 93 | |
| kidney | 12 / 211777 | 56 | |
| larynx | 2 / 24145 | 82 | |
| liver | 21 / 207743 | 101 | |
| lung | 44 / 336974 | 130 | |
| lymph | 4 / 44270 | 90 | |
| lymph node | 9 / 91610 | 98 | |
| mammary gland | 23 / 153271 | 150 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 11 / 102051 | 107 | |
| pancreas | 18 / 214812 | 83 | |
| parathyroid | 2 / 20539 | 97 | |
| pharynx | 12 / 41328 | 290 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 23 / 280825 | 81 | |
| prostate | 15 / 189345 | 79 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 19 / 210574 | 90 | |
| spleen | 9 / 53952 | 166 | |
| stomach | 11 / 96619 | 113 | |
| testis | 11 / 330442 | 33 | |
| thymus | 12 / 81131 | 147 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 2 / 16999 | 117 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 42 / 232878 | 180 | |
| vascular | 1 / 51780 | 19 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 3 / 40015 | 74 | |
| bladder | 0 / 29757 | 0 | |
| blood | 5 / 123478 | 40 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 4 / 1100989 | 3 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 7 / 215722 | 32 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 4 / 211054 | 18 | |
| heart | 1 / 89626 | 11 | |
| intestine | 4 / 234472 | 17 | |
| kidney | 0 / 211777 | 0 | |
| larynx | 0 / 24145 | 0 | |
| liver | 12 / 207743 | 57 | |
| lung | 5 / 336974 | 14 | |
| lymph | 6 / 44270 | 135 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 6 / 153271 | 39 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 2 / 107715 | 18 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 2 / 214812 | 9 | |
| parathyroid | 1 / 20539 | 48 | |
| pharynx | 5 / 41328 | 120 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 4 / 280825 | 14 | |
| prostate | 3 / 189345 | 15 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 5 / 210574 | 23 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 3 / 96619 | 31 | |
| testis | 1 / 330442 | 3 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 4 / 16999 | 235 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 12 / 232878 | 51 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 201762_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 3842.05 |  |
| Adipocyte | 152.5 | |
| AdrenalCortex | 462.6 | |
| Adrenalgland | 322.65 | |
| Amygdala | 49.95 | |
| Appendix | 103.1 | |
| AtrioventricularNode | 37.7 | |
| BDCA4+_DentriticCells | 1311.1 | |
| Bonemarrow | 203.2 | |
| BronchialEpithelialCells | 376.5 | |
| CD105+_Endothelial | 387.4 | |
| CD14+_Monocytes | 1333.3 | |
| CD19+_BCells(neg._sel.) | 799.75 | |
| CD33+_Myeloid | 1172.35 | |
| CD34+ | 897.7 | |
| CD4+_Tcells | 1176.6 | |
| CD56+_NKCells | 1254.25 | |
| CD71+_EarlyErythroid | 107.4 | |
| CD8+_Tcells | 1133.25 | |
| CardiacMyocytes | 138.3 | |
| Caudatenucleus | 54.25 | |
| Cerebellum | 37.55 | |
| CerebellumPeduncles | 58.25 | |
| CiliaryGanglion | 26.8 | |
| CingulateCortex | 61.45 | |
| Colorectaladenocarcinoma | 252.35 | |
| DorsalRootGanglion | 82.95 | |
| FetalThyroid | 253 | |
| Fetalbrain | 80.2 | |
| Fetalliver | 80.2 | |
| Fetallung | 273.85 | |
| GlobusPallidus | 48.85 | |
| Heart | 144 | |
| Hypothalamus | 163.65 | |
| Kidney | 114.5 | |
| Leukemia_chronicMyelogenousK-562 | 208.95 | |
| Leukemia_promyelocytic-HL-60 | 744 | |
| Leukemialymphoblastic(MOLT-4) | 595.65 | |
| Liver | 227.9 | |
| Lung | 278.5 | |
| Lymphnode | 570.4 | |
| Lymphoma_burkitts(Daudi) | 946.75 | |
| Lymphoma_burkitts(Raji) | 1063.4 | |
| MedullaOblongata | 34.55 | |
| OccipitalLobe | 53.9 | |
| OlfactoryBulb | 135.6 | |
| Ovary | 115.7 | |
| Pancreas | 286 | |
| PancreaticIslet | 304.8 | |
| ParietalLobe | 52.35 | |
| Pituitary | 285.3 | |
| Placenta | 298.95 | |
| Pons | 60.8 | |
| PrefrontalCortex | 157.2 | |
| Prostate | 291.9 | |
| Salivarygland | 238.8 | |
| SkeletalMuscle | 60.15 | |
| Skin | 77.2 | |
| SmoothMuscle | 498.7 | |
| Spinalcord | 101.95 | |
| SubthalamicNucleus | 29.95 | |
| SuperiorCervicalGanglion | 46.6 | |
| TemporalLobe | 33.5 | |
| Testis | 91.2 | |
| TestisGermCell | 157.45 | |
| TestisIntersitial | 59.9 | |
| TestisLeydigCell | 142.6 | |
| TestisSeminiferousTubule | 131.5 | |
| Thalamus | 94.35 | |
| Thymus | 507.3 | |
| Thyroid | 228.9 | |
| Tongue | 201.55 | |
| Tonsil | 579.1 | |
| Trachea | 161.25 | |
| TrigeminalGanglion | 40.9 | |
| Uterus | 139.1 | |
| UterusCorpus | 77.8 | |
| WholeBlood | 835.9 | |
| Wholebrain | 82.2 | |
| colon | 523.8 | |
| pineal_day | 413.26 | |
| pineal_night | 387.82 | |
| retina | 231.225 | |
| small_intestine | 736.75 | |
- Probe name: A_32_P15169
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 10.16 ± 0.14 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 10.12 ± 0.07 | |
| Basal Part of Pons | 9.71 ± 0.18 | |
| Cerebellar Cortex | 9.95 ± 0.19 | |
| Cerebellar Nuclei | 10.03 ± 0.17 | |
| Claustrum | 10.1 ± 0.25 | |
| Epithalamus | 10.35 ± 0.27 | |
| Frontal Lobe | 10.06 ± 0.27 | |
| Globus Pallidus | 10.49 ± 0.21 | |
| Hypothalamus | 10.5 ± 0.26 | |
| Insula | 10.33 ± 0.27 | |
| Limbic Lobe | 10.05 ± 0.26 | |
| Mesencephalon | 10.13 ± 0.23 | |
| Myelencephalon | 10.1 ± 0.29 | |
| Occipital Lobe | 9.88 ± 0.22 | |
| Parietal Lobe | 9.97 ± 0.2 | |
| Pontine Tegmentum | 10.14 ± 0.23 | |
| Striatum | 10.14 ± 0.2 | |
| Subthalamus | 10.08 ± 0.24 | |
| Temporal Lobe | 10.17 ± 0.23 | |
| Thalamus | 9.97 ± 0.2 | |
| White Matter | 9.96 ± 0.19 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Psme2 | CB | Cerebellum | 11.98 | |
| 13.27 | | |||
| Psme2 | CTX | Cerebral cortex | 8.26 | |
| 6.23 | | |||
| Psme2 | HIP | Hippocampal region | 11.77 | |
| 12.47 | | |||
| Psme2 | HPF | Hippocampal formation | 9.57 | |
| 9.31 | | |||
| Psme2 | HY | Hypothalamus | 5.92 | |
| 5.39 | | |||
| Psme2 | LSX | Lateral septal complex | 6.43 | |
| 5.18 | | |||
| Psme2 | MB | Midbrain | 5.75 | |
| 6.02 | | |||
| Psme2 | MY | Medulla | 10.01 | |
| 12.01 | | |||
| Psme2 | OLF | Olfactory bulb | 11.99 | |
| 9.44 | | |||
| Psme2 | P | Pons | 5.61 | |
| 6.47 | | |||
| Psme2 | PAL | Pallidum | 5.74 | |
| 5.71 | | |||
| Psme2 | RHP | Retrohippocampal region | 6.64 | |
| 5.5 | | |||
| Psme2 | sAMY | Striatum-like amygdalar nuclei | 5.68 | |
| 4.36 | | |||
| Psme2 | STR | Striatum | 3.77 | |
| 3.21 | | |||
| Psme2 | STRd | Striatum dorsal region | 2.66 | |
| 2.57 | | |||
| Psme2 | STRv | Striatum ventral region | 5.12 | |
| 3.53 | | |||
| Psme2 | TH | Thalamus | 5.85 | |
| 5.12 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00000572 | 15 | 189 | 203 | ALVHERDEAAYGELR | Peptide Atlas |
| PSME2_HUMAN_0 | 0 | 0 | 0 | AFYAELYHIISSNLEK | PRIDE |
| PSME2_HUMAN_0 | 0 | 0 | 0 | ALVHERDEAAYGELR | PRIDE |
| PSME2_HUMAN_0 | 0 | 0 | 0 | APLDIPIPDPPPKDDEMETDKQEK | PRIDE |
| PSME2_HUMAN_0 | 0 | 0 | 0 | CILVITWIQHLIPK | PRIDE |
| PSME2_HUMAN_0 | 0 | 0 | 0 | IEDGNDFGVAIQEK | PRIDE |
| PSME2_HUMAN_0 | 0 | 0 | 0 | IIYLNQLLQEDSLNVADLTSLR | PRIDE |
| PSME2_HUMAN_0 | 0 | 0 | 0 | QNLFQEAEEFLYR | PRIDE |
| PSME2_HUMAN_0 | 0 | 0 | 0 | TKVEAFQTTISK | PRIDE |
| PSME2_HUMAN_0 | 0 | 0 | 0 | VEAFQTTISK | PRIDE |
| PSME2_HUMAN_0 | 0 | 0 | 0 | VLSLLALVKPEVWTLK | PRIDE |
| PSME2_HUMAN_117 | 14 | 117 | 130 | CILVITWIQHLIPK | PRIDE |
| PSME2_HUMAN_131 | 14 | 131 | 144 | IEDGNDFGVAIQEK | PRIDE |
| PSME2_HUMAN_14 | 20 | 14 | 33 | KQVEVFRQNLFQEAEEFLYR | PRIDE |
| PSME2_HUMAN_154 | 12 | 154 | 165 | TKVEAFQTTISK | PRIDE |
| PSME2_HUMAN_156 | 10 | 156 | 165 | VEAFQTTISK | PRIDE |
| PSME2_HUMAN_166 | 11 | 166 | 176 | YFSERGDAVAK | PRIDE |
| PSME2_HUMAN_188 | 15 | 188 | 202 | ALVHERDEAAYGELR | PRIDE |
| PSME2_HUMAN_2 | 7 | 2 | 8 | AKPCGVR | PRIDE |
| PSME2_HUMAN_21 | 13 | 21 | 33 | QNLFQEAEEFLYR | PRIDE |
| PSME2_HUMAN_210 | 16 | 210 | 225 | AFYAELYHIISSNLEK | PRIDE |
| PSME2_HUMAN_22 | 13 | 22 | 34 | QNLFQEAEEFLYR | PRIDE |
| PSME2_HUMAN_39 | 22 | 39 | 60 | IIYLNQLLQEDSLNVADLTSLR | PRIDE |
| PSME2_HUMAN_61 | 24 | 61 | 84 | APLDIPIPDPPPKDDEMETDKQEK | PRIDE |
| PSME2_HUMAN_90 | 9 | 90 | 98 | CGFLPGNEK | PRIDE |
| PSME2_HUMAN_99 | 16 | 99 | 114 | VLSLLALVKPEVWTLK | PRIDE |
| PSME2_HUMAN_99 | 18 | 99 | 116 | VLSLLALVKPEVWTLKEK | PRIDE |