AutismKB 2.0

Annotation Detail for SLC45A4


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Basic Information Top
Gene Symbol:SLC45A4 ( KIAA1126 )
Gene Full Name: solute carrier family 45, member 4
Band: 8q24.3
Quick LinksEntrez ID:57210; OMIM: NA; Uniprot ID:C9JFW9_HUMAN; ENSEMBL ID: ENSG00000022567; HGNC ID: 29196
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst4 / 6231964
fetus16 / 56401228
neonate0 / 310970 
infant1 / 2362042
juvenile1 / 5555617
adult51 / 193912126
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor11 / 11424696
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor8 / 26384530
glioma2 / 10688318
head and neck tumor5 / 13630236
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal98 / 336030729
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites2 / 4001549
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain25 / 110098922
cervix0 / 481710 
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue7 / 21572232
esophagus0 / 202090 
eye4 / 21105418
heart0 / 896260 
intestine19 / 23447281
kidney16 / 21177775
larynx0 / 241450 
liver0 / 2077430 
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth3 / 6705244
muscle1 / 1077159
nerve1 / 1576863
ovary6 / 10205158
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta7 / 28082524
prostate2 / 18934510
salivary gland1 / 2015549
skin0 / 2105740 
spleen0 / 539520 
stomach2 / 9661920
testis12 / 33044236
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_56_PI416573500
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.6 ± 0.56
Basal Forebrain4.16 ± 0.7
Basal Part of Pons5.28 ± 0.48
Cerebellar Cortex4.71 ± 0.39
Cerebellar Nuclei4.56 ± 0.45
Claustrum4.03 ± 0.74
Epithalamus4.24 ± 0.65
Frontal Lobe4.58 ± 0.63
Globus Pallidus3.73 ± 0.59
Hypothalamus3.95 ± 0.46
Insula4.53 ± 0.46
Limbic Lobe4.88 ± 0.49
Mesencephalon4.53 ± 0.67
Myelencephalon4.53 ± 0.71
Occipital Lobe5.29 ± 0.43
Parietal Lobe4.94 ± 0.48
Pontine Tegmentum4.43 ± 0.6
Striatum3.66 ± 0.6
Subthalamus4.96 ± 0.36
Temporal Lobe4.6 ± 0.52
Thalamus4.29 ± 0.64
White Matter2.5 ± 1.14
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Slc45a4CBCerebellum13.44
14.75
Slc45a4CTXCerebral cortex23.64
17.09
Slc45a4HIPHippocampal region13.17
13.25
Slc45a4HPFHippocampal formation13.65
12.3
Slc45a4HYHypothalamus5.48
4.81
Slc45a4LSXLateral septal complex1.64
1.14
Slc45a4MBMidbrain13.01
12.32
Slc45a4MYMedulla19.04
21.48
Slc45a4OLFOlfactory bulb17
12.03
Slc45a4PPons13.47
15.19
Slc45a4PALPallidum7.48
6.89
Slc45a4RHPRetrohippocampal region14.78
11.26
Slc45a4sAMYStriatum-like amygdalar nuclei9.58
7.59
Slc45a4STRStriatum5.25
3.93
Slc45a4STRdStriatum dorsal region3.97
3.09
Slc45a4STRvStriatum ventral region8.46
5.53
Slc45a4THThalamus20.01
16.13
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018