Annotation Detail for SMEK2
Basic Information Top
| Gene Symbol: | SMEK2 ( FLFL2,FLJ31474,KIAA1387,PP4R3B,PSY2,smk1 ) |
|---|---|
| Gene Full Name: | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| Band: | 2p16.1 |
| Quick Links | Entrez ID:57223; OMIM: 610352; Uniprot ID:P4R3B_HUMAN; ENSEMBL ID: ENSG00000138041; HGNC ID: |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.516182
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 5 / 70761 | 70 |  |
| blastocyst | 3 / 62319 | 48 |  |
| fetus | 48 / 564012 | 85 | |
| neonate | 2 / 31097 | 64 | |
| infant | 2 / 23620 | 84 | |
| juvenile | 3 / 55556 | 53 | |
| adult | 191 / 1939121 | 98 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 3 / 12794 | 234 |  |
| bladder carcinoma | 2 / 17475 | 114 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 5 / 34366 | 145 | |
| chondrosarcoma | 3 / 82823 | 36 | |
| colorectal tumor | 3 / 114246 | 26 | |
| esophageal tumor | 1 / 17290 | 57 | |
| gastrointestinal tumor | 6 / 119369 | 50 | |
| germ cell tumor | 43 / 263845 | 162 | |
| glioma | 6 / 106883 | 56 | |
| head and neck tumor | 14 / 136302 | 102 | |
| kidney tumor | 8 / 68959 | 116 | |
| leukemia | 9 / 95842 | 93 | |
| liver tumor | 5 / 96359 | 51 | |
| lung tumor | 4 / 103127 | 38 | |
| lymphoma | 6 / 71755 | 83 | |
| non-neoplasia | 10 / 97250 | 102 | |
| normal | 273 / 3360307 | 81 | |
| ovarian tumor | 3 / 76682 | 39 | |
| pancreatic tumor | 5 / 104616 | 47 | |
| primitive neuroectodermal tumor of the CNS | 6 / 125680 | 47 | |
| prostate cancer | 5 / 102680 | 48 | |
| retinoblastoma | 7 / 46356 | 151 | |
| skin tumor | 4 / 124949 | 32 | |
| soft tissue/muscle tissue tumor | 6 / 125191 | 47 | |
| uterine tumor | 7 / 90257 | 77 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 | |
| adrenal gland | 4 / 33197 | 120 | |
| ascites | 3 / 40015 | 74 | |
| bladder | 5 / 29757 | 168 | |
| blood | 10 / 123478 | 80 | |
| bone | 4 / 71655 | 55 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 95 / 1100989 | 86 | |
| cervix | 9 / 48171 | 186 | |
| connective tissue | 4 / 149255 | 26 | |
| ear | 3 / 16212 | 185 | |
| embryonic tissue | 15 / 215722 | 69 | |
| esophagus | 2 / 20209 | 98 | |
| eye | 21 / 211054 | 99 | |
| heart | 1 / 89626 | 11 | |
| intestine | 6 / 234472 | 25 | |
| kidney | 17 / 211777 | 80 | |
| larynx | 1 / 24145 | 41 | |
| liver | 13 / 207743 | 62 | |
| lung | 16 / 336974 | 47 | |
| lymph | 2 / 44270 | 45 | |
| lymph node | 16 / 91610 | 174 | |
| mammary gland | 13 / 153271 | 84 | |
| mouth | 3 / 67052 | 44 | |
| muscle | 14 / 107715 | 129 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 5 / 102051 | 48 | |
| pancreas | 10 / 214812 | 46 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 42 / 280825 | 149 | |
| prostate | 10 / 189345 | 52 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 7 / 210574 | 33 | |
| spleen | 2 / 53952 | 37 | |
| stomach | 3 / 96619 | 31 | |
| testis | 55 / 330442 | 166 | |
| thymus | 14 / 81131 | 172 | |
| thyroid | 11 / 47473 | 231 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 15 / 52413 | 286 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 22 / 232878 | 94 | |
| vascular | 7 / 51780 | 135 | |
Microarray in - Probe name: CUST_10323_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 7.88 ± 0.23 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 7.82 ± 0.11 | |
| Basal Part of Pons | 7.26 ± 0.18 | |
| Cerebellar Cortex | 7.86 ± 0.21 | |
| Cerebellar Nuclei | 7.32 ± 0.26 | |
| Claustrum | 7.9 ± 0.25 | |
| Epithalamus | 8.11 ± 0.36 | |
| Frontal Lobe | 7.49 ± 0.28 | |
| Globus Pallidus | 7.84 ± 0.23 | |
| Hypothalamus | 7.5 ± 0.22 | |
| Insula | 7.58 ± 0.26 | |
| Limbic Lobe | 7.71 ± 0.35 | |
| Mesencephalon | 7.64 ± 0.24 | |
| Myelencephalon | 7.63 ± 0.31 | |
| Occipital Lobe | 7.88 ± 0.27 | |
| Parietal Lobe | 7.66 ± 0.29 | |
| Pontine Tegmentum | 7.69 ± 0.28 | |
| Striatum | 7.7 ± 0.34 | |
| Subthalamus | 7.33 ± 0.34 | |
| Temporal Lobe | 7.59 ± 0.26 | |
| Thalamus | 7.53 ± 0.2 | |
| White Matter | 8.31 ± 0.24 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| AW011752 | CB | Cerebellum | 14.2 | |
| 19.96 | | |||
| AW011752 | CTX | Cerebral cortex | 29 | |
| 23.16 | | |||
| AW011752 | HIP | Hippocampal region | 28.84 | |
| 36 | | |||
| AW011752 | HPF | Hippocampal formation | 32.9 | |
| 35.81 | | |||
| AW011752 | HY | Hypothalamus | 2.02 | |
| 1.99 | | |||
| AW011752 | LSX | Lateral septal complex | 0.1 | |
| 0 | | |||
| AW011752 | MB | Midbrain | 4.25 | |
| 4.79 | | |||
| AW011752 | MY | Medulla | 9.28 | |
| 10.35 | | |||
| AW011752 | OLF | Olfactory bulb | 17.42 | |
| 14.76 | | |||
| AW011752 | P | Pons | 3.64 | |
| 4.24 | | |||
| AW011752 | PAL | Pallidum | 0.83 | |
| 0.91 | | |||
| AW011752 | RHP | Retrohippocampal region | 43.92 | |
| 38.95 | | |||
| AW011752 | sAMY | Striatum-like amygdalar nuclei | 5 | |
| 3.6 | | |||
| AW011752 | STR | Striatum | 4.7 | |
| 3.64 | | |||
| AW011752 | STRd | Striatum dorsal region | 3.82 | |
| 2.95 | | |||
| AW011752 | STRv | Striatum ventral region | 8.54 | |
| 6.4 | | |||
| AW011752 | TH | Thalamus | 5.73 | |
| 5.27 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00524452 | 18 | 104 | 121 | DPSVEVTQDLIDESEEER | Peptide Atlas |