AutismKB 2.0

Annotation Detail for SNX14


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Basic Information Top
Gene Symbol:SNX14 ( MGC13217,RGS-PX2 )
Gene Full Name: sorting nexin 14
Band: 6q14.3
Quick LinksEntrez ID:57231; OMIM: NA; Uniprot ID:SNX14_HUMAN; ENSEMBL ID: ENSG00000135317; HGNC ID: 14977
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst1 / 6231916
fetus35 / 56401262
neonate0 / 310970 
infant0 / 236200 
juvenile5 / 5555689
adult134 / 193912169
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor6 / 9417863
cervical tumor0 / 343660 
chondrosarcoma8 / 8282396
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor13 / 26384549
glioma6 / 10688356
head and neck tumor12 / 13630288
kidney tumor2 / 6895929
leukemia5 / 9584252
liver tumor7 / 9635972
lung tumor1 / 1031279
lymphoma5 / 7175569
non-neoplasia10 / 97250102
normal193 / 336030757
ovarian tumor9 / 76682117
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer5 / 10268048
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites5 / 40015124
bladder1 / 2975733
blood9 / 12347872
bone8 / 71655111
bone marrow1 / 4880120
brain58 / 110098952
cervix2 / 4817141
connective tissue13 / 14925587
ear0 / 162120 
embryonic tissue10 / 21572246
esophagus0 / 202090 
eye9 / 21105442
heart3 / 8962633
intestine8 / 23447234
kidney15 / 21177770
larynx0 / 241450 
liver12 / 20774357
lung18 / 33697453
lymph1 / 4427022
lymph node4 / 9161043
mammary gland9 / 15327158
mouth2 / 6705229
muscle2 / 10771518
nerve1 / 1576863
ovary12 / 102051117
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta13 / 28082546
prostate4 / 18934521
salivary gland1 / 2015549
skin6 / 21057428
spleen4 / 5395274
stomach5 / 9661951
testis70 / 330442211
thymus7 / 8113186
thyroid10 / 47473210
tonsil0 / 169990 
trachea6 / 52413114
umbilical cord0 / 136800 
uterus18 / 23287877
vascular5 / 5178096
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1017_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.61 ± 0.2
Basal Forebrain8.52 ± 0.18
Basal Part of Pons8.66 ± 0.26
Cerebellar Cortex8.76 ± 0.23
Cerebellar Nuclei8.9 ± 0.33
Claustrum8.63 ± 0.36
Epithalamus8.83 ± 0.24
Frontal Lobe8.66 ± 0.25
Globus Pallidus8.51 ± 0.22
Hypothalamus8.83 ± 0.36
Insula8.61 ± 0.21
Limbic Lobe8.57 ± 0.34
Mesencephalon8.69 ± 0.33
Myelencephalon8.58 ± 0.27
Occipital Lobe8.64 ± 0.32
Parietal Lobe8.65 ± 0.26
Pontine Tegmentum8.61 ± 0.29
Striatum8.12 ± 0.25
Subthalamus9.01 ± 0.21
Temporal Lobe8.64 ± 0.27
Thalamus8.53 ± 0.22
White Matter8.86 ± 0.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Snx14CBCerebellum57.04
100
Snx14CTXCerebral cortex100
100
Snx14HIPHippocampal region86.12
100
Snx14HPFHippocampal formation93.4
100
Snx14HYHypothalamus100
97.91
Snx14LSXLateral septal complex100
100
Snx14MBMidbrain100
100
Snx14MYMedulla93.9
100
Snx14OLFOlfactory bulb94.28
100
Snx14PPons92.53
100
Snx14PALPallidum97.16
100
Snx14RHPRetrohippocampal region100
100
Snx14sAMYStriatum-like amygdalar nuclei100
93.93
Snx14STRStriatum100
99.05
Snx14STRdStriatum dorsal region100
100
Snx14STRvStriatum ventral region100
85.94
Snx14THThalamus100
100
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018