AutismKB 2.0

Annotation Detail for PTGDR


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Basic Information Top
Gene Symbol:PTGDR ( AS1,ASRT1,DP,DP1,MGC49004 )
Gene Full Name: prostaglandin D2 receptor (DP)
Band: 14q22.1
Quick LinksEntrez ID:5729; OMIM: 604687; Uniprot ID:PD2R_HUMAN; ENSEMBL ID: ENSG00000168229; HGNC ID: 9591
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult4 / 19391212
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal5 / 33603071
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine2 / 2344728
kidney0 / 2117770 
larynx0 / 241450 
liver1 / 2077434
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 215894_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.85
Adipocyte5.85
AdrenalCortex6.75
Adrenalgland5.05
Amygdala5.9
Appendix6.35
AtrioventricularNode5.3
BDCA4+_DentriticCells5.9
Bonemarrow6.3
BronchialEpithelialCells5.65
CD105+_Endothelial5.85
CD14+_Monocytes6.25
CD19+_BCells(neg._sel.)6.1
CD33+_Myeloid7.45
CD34+7.25
CD4+_Tcells6.55
CD56+_NKCells626.85
CD71+_EarlyErythroid5.55
CD8+_Tcells16.95
CardiacMyocytes8.1
Caudatenucleus5.35
Cerebellum4.8
CerebellumPeduncles6.9
CiliaryGanglion4.8
CingulateCortex6.35
Colorectaladenocarcinoma5.9
DorsalRootGanglion5
FetalThyroid5.75
Fetalbrain5.9
Fetalliver5.1
Fetallung4.6
GlobusPallidus4.6
Heart8.6
Hypothalamus6.2
Kidney5.05
Leukemia_chronicMyelogenousK-5625.3
Leukemia_promyelocytic-HL-605.2
Leukemialymphoblastic(MOLT-4)4.65
Liver8.1
Lung6.45
Lymphnode5.4
Lymphoma_burkitts(Daudi)7.55
Lymphoma_burkitts(Raji)8.65
MedullaOblongata5.25
OccipitalLobe5.25
OlfactoryBulb4.65
Ovary4.05
Pancreas4.9
PancreaticIslet6.35
ParietalLobe6.55
Pituitary6.8
Placenta5.85
Pons5.8
PrefrontalCortex7.1
Prostate6.8
Salivarygland4.8
SkeletalMuscle8
Skin5.05
SmoothMuscle6.6
Spinalcord6.3
SubthalamicNucleus6.45
SuperiorCervicalGanglion8
TemporalLobe5.45
Testis5
TestisGermCell4.8
TestisIntersitial5
TestisLeydigCell5.9
TestisSeminiferousTubule5.05
Thalamus6
Thymus4.45
Thyroid7.2
Tongue6.2
Tonsil5.8
Trachea4.95
TrigeminalGanglion6.75
Uterus4.8
UterusCorpus7
WholeBlood6.85
Wholebrain4.8
colon8.15
pineal_day7.24
pineal_night7.1
retina7.15
small_intestine5.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P3083
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.43 ± 1.17
Basal Forebrain2.62 ± 0.65
Basal Part of Pons2.06 ± 0.94
Cerebellar Cortex1.99 ± 0.66
Cerebellar Nuclei3.21 ± 0.72
Claustrum3.09 ± 0.68
Epithalamus4.54 ± 0.83
Frontal Lobe2.36 ± 0.92
Globus Pallidus4.28 ± 0.49
Hypothalamus2.87 ± 1.15
Insula2.17 ± 0.73
Limbic Lobe2.27 ± 0.82
Mesencephalon2.88 ± 0.96
Myelencephalon2.61 ± 0.98
Occipital Lobe2.59 ± 1
Parietal Lobe2.54 ± 0.97
Pontine Tegmentum2.51 ± 0.92
Striatum3.15 ± 0.92
Subthalamus2.5 ± 1.14
Temporal Lobe2.28 ± 0.94
Thalamus2.33 ± 0.68
White Matter3.15 ± 1.18
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PtgdrCBCerebellum0
0
PtgdrCTXCerebral cortex0
0
PtgdrHIPHippocampal region0
0
PtgdrHPFHippocampal formation0
0
PtgdrHYHypothalamus0
0
PtgdrLSXLateral septal complex0
0
PtgdrMBMidbrain0
0
PtgdrMYMedulla0
0
PtgdrOLFOlfactory bulb0
0
PtgdrPPons0
0
PtgdrPALPallidum0
0
PtgdrRHPRetrohippocampal region0
0
PtgdrsAMYStriatum-like amygdalar nuclei0
0
PtgdrSTRStriatum0
0
PtgdrSTRdStriatum dorsal region0
0
PtgdrSTRvStriatum ventral region0
0
PtgdrTHThalamus0
0
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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