AutismKB 2.0

Annotation Detail for PTGDS


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Basic Information Top
Gene Symbol:PTGDS ( L-PGDS,LPGDS,PDS,PGD2,PGDS,PGDS2 )
Gene Full Name: prostaglandin D2 synthase 21kDa (brain)
Band: 9q34.3
Quick LinksEntrez ID:5730; OMIM: 176803; Uniprot ID:PTGDS_HUMAN; ENSEMBL ID: ENSG00000107317; HGNC ID: 9592
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus48 / 56401285
neonate0 / 310970 
infant1 / 2362042
juvenile13 / 55556233
adult614 / 1939121316
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor6 / 26384522
glioma14 / 106883130
head and neck tumor0 / 1363020 
kidney tumor4 / 6895958
leukemia2 / 9584220
liver tumor3 / 9635931
lung tumor2 / 10312719
lymphoma5 / 7175569
non-neoplasia20 / 97250205
normal689 / 3360307205
ovarian tumor11 / 76682143
pancreatic tumor16 / 104616152
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor15 / 90257166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone5 / 7165569
bone marrow1 / 4880120
brain490 / 1100989445
cervix0 / 481710 
connective tissue7 / 14925546
ear1 / 1621261
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye209 / 211054990
heart26 / 89626290
intestine4 / 23447217
kidney7 / 21177733
larynx0 / 241450 
liver3 / 20774314
lung23 / 33697468
lymph0 / 442700 
lymph node4 / 9161043
mammary gland12 / 15327178
mouth0 / 670520 
muscle5 / 10771546
nerve13 / 15768824
ovary12 / 102051117
pancreas25 / 214812116
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta21 / 28082574
prostate19 / 189345100
salivary gland0 / 201550 
skin0 / 2105740 
spleen4 / 5395274
stomach6 / 9661962
testis74 / 330442223
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus17 / 23287872
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211748_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts21.6
Adipocyte54.55
AdrenalCortex557.55
Adrenalgland302.6
Amygdala7445.05
Appendix953.65
AtrioventricularNode7275
BDCA4+_DentriticCells5287.55
Bonemarrow159.2
BronchialEpithelialCells51.4
CD105+_Endothelial185.35
CD14+_Monocytes102.45
CD19+_BCells(neg._sel.)27.15
CD33+_Myeloid15.65
CD34+18.85
CD4+_Tcells138.65
CD56+_NKCells1657.8
CD71+_EarlyErythroid46.85
CD8+_Tcells107.15
CardiacMyocytes124.8
Caudatenucleus9008.3
Cerebellum5793.2
CerebellumPeduncles7976.85
CiliaryGanglion4805.75
CingulateCortex6053.1
Colorectaladenocarcinoma116.55
DorsalRootGanglion5736.2
FetalThyroid110.95
Fetalbrain219.25
Fetalliver90.6
Fetallung129.05
GlobusPallidus4522.5
Heart16362.05
Hypothalamus12017.45
Kidney376.85
Leukemia_chronicMyelogenousK-56245.05
Leukemia_promyelocytic-HL-6025.15
Leukemialymphoblastic(MOLT-4)29.75
Liver362.5
Lung3752.15
Lymphnode2198.1
Lymphoma_burkitts(Daudi)46.2
Lymphoma_burkitts(Raji)75.35
MedullaOblongata7162.3
OccipitalLobe10051.3
OlfactoryBulb9767.55
Ovary103.1
Pancreas121.75
PancreaticIslet218.9
ParietalLobe10116.05
Pituitary2762.85
Placenta952.2
Pons6199.15
PrefrontalCortex14561.85
Prostate2691.9
Salivarygland182.65
SkeletalMuscle194.55
Skin155
SmoothMuscle102
Spinalcord16168.25
SubthalamicNucleus5254.45
SuperiorCervicalGanglion9605.1
TemporalLobe5289.7
Testis12356.85
TestisGermCell16868.45
TestisIntersitial13672.3
TestisLeydigCell10759.55
TestisSeminiferousTubule13479.6
Thalamus9161.4
Thymus1141.6
Thyroid319.25
Tongue119.85
Tonsil2109.6
Trachea271.35
TrigeminalGanglion12054.15
Uterus1474.25
UterusCorpus2190
WholeBlood146.7
Wholebrain8745.05
colon144.1
pineal_day3774.08
pineal_night5016.96
retina21277.775
small_intestine77.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16789_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala13.25 ± 0.33
Basal Forebrain13.54 ± 0.25
Basal Part of Pons13.18 ± 0.38
Cerebellar Cortex12.86 ± 0.18
Cerebellar Nuclei13.96 ± 0.49
Claustrum12.94 ± 0.34
Epithalamus13.58 ± 0.41
Frontal Lobe13.3 ± 0.54
Globus Pallidus14.85 ± 0.37
Hypothalamus13.44 ± 0.39
Insula12.93 ± 0.42
Limbic Lobe12.94 ± 0.65
Mesencephalon13.54 ± 0.43
Myelencephalon13.45 ± 0.44
Occipital Lobe13.31 ± 0.43
Parietal Lobe13.33 ± 0.38
Pontine Tegmentum13.54 ± 0.4
Striatum14.09 ± 0.53
Subthalamus13.42 ± 0.1
Temporal Lobe13.17 ± 0.44
Thalamus13.85 ± 0.3
White Matter15.05 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PtgdsCBCerebellum67.15
99.48
PtgdsCTXCerebral cortex56.69
67.68
PtgdsHIPHippocampal region56.26
81.2
PtgdsHPFHippocampal formation63.29
80.52
PtgdsHYHypothalamus85.65
91.35
PtgdsLSXLateral septal complex72.07
74.79
PtgdsMBMidbrain100
100
PtgdsMYMedulla100
100
PtgdsOLFOlfactory bulb56.47
67.4
PtgdsPPons100
100
PtgdsPALPallidum98
97.86
PtgdsRHPRetrohippocampal region77.95
80.87
PtgdssAMYStriatum-like amygdalar nuclei64.15
74.44
PtgdsSTRStriatum62.7
69.66
PtgdsSTRdStriatum dorsal region64.59
70.9
PtgdsSTRvStriatum ventral region49.55
54.87
PtgdsTHThalamus96.85
98.62
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00027977 19 67 85 SVVAPATDGGLNLTSTFLR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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