AutismKB 2.0

Annotation Detail for PTGER3


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Basic Information Top
Gene Symbol:PTGER3 ( EP3,EP3-I,EP3-II,EP3-III,EP3-IV,EP3e,MGC141828,MGC141829,MGC27302 )
Gene Full Name: prostaglandin E receptor 3 (subtype EP3)
Band: 1p31.1
Quick LinksEntrez ID:5733; OMIM: 176806; Uniprot ID:PE2R3_HUMAN; ENSEMBL ID: ENSG00000050628; HGNC ID: 9595
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus9 / 56401215
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult45 / 193912123
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal84 / 336030724
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain6 / 11009895
cervix0 / 481710 
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine1 / 2344724
kidney47 / 211777221
larynx2 / 2414582
liver0 / 2077430 
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland5 / 15327132
mouth0 / 670520 
muscle7 / 10771564
nerve1 / 1576863
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach1 / 9661910
testis0 / 3304420 
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus15 / 23287864
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 211909_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts61.8
Adipocyte31.35
AdrenalCortex88.1
Adrenalgland35.9
Amygdala24.6
Appendix96.05
AtrioventricularNode135.9
BDCA4+_DentriticCells22.5
Bonemarrow51.25
BronchialEpithelialCells27.85
CD105+_Endothelial47.05
CD14+_Monocytes57.15
CD19+_BCells(neg._sel.)52.95
CD33+_Myeloid39.4
CD34+50.95
CD4+_Tcells36.55
CD56+_NKCells33.1
CD71+_EarlyErythroid40.05
CD8+_Tcells27.15
CardiacMyocytes107.95
Caudatenucleus51.15
Cerebellum27.3
CerebellumPeduncles67.5
CiliaryGanglion117.8
CingulateCortex60.1
Colorectaladenocarcinoma252.55
DorsalRootGanglion83.8
FetalThyroid67.15
Fetalbrain35.45
Fetalliver29.25
Fetallung24.75
GlobusPallidus161.45
Heart254.95
Hypothalamus38.2
Kidney40.35
Leukemia_chronicMyelogenousK-56228.7
Leukemia_promyelocytic-HL-6038.75
Leukemialymphoblastic(MOLT-4)30.05
Liver74.75
Lung32.65
Lymphnode22.05
Lymphoma_burkitts(Daudi)72.55
Lymphoma_burkitts(Raji)278.6
MedullaOblongata28.45
OccipitalLobe41.3
OlfactoryBulb26.35
Ovary55.6
Pancreas73.1
PancreaticIslet46.9
ParietalLobe51.25
Pituitary52.3
Placenta43.25
Pons49.5
PrefrontalCortex44.4
Prostate32.1
Salivarygland80.05
SkeletalMuscle94.95
Skin104.8
SmoothMuscle45.95
Spinalcord39.25
SubthalamicNucleus105.05
SuperiorCervicalGanglion97.3
TemporalLobe53.45
Testis27.35
TestisGermCell24.25
TestisIntersitial41.4
TestisLeydigCell56.05
TestisSeminiferousTubule60.05
Thalamus85.9
Thymus20.9
Thyroid27.1
Tongue87
Tonsil50.9
Trachea27.9
TrigeminalGanglion94.85
Uterus26.35
UterusCorpus55.3
WholeBlood31.15
Wholebrain18.4
colon31.85
pineal_day186.78
pineal_night212.44
retina92.925
small_intestine38.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1144_PI416379584
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.27 ± 0.94
Basal Forebrain1.48 ± 0.25
Basal Part of Pons1.18 ± 0.36
Cerebellar Cortex1.3 ± 0.7
Cerebellar Nuclei1.74 ± 0.76
Claustrum2.24 ± 0.78
Epithalamus1.16 ± 0.75
Frontal Lobe1.32 ± 0.56
Globus Pallidus2.07 ± 0.37
Hypothalamus1.65 ± 0.62
Insula1.51 ± 0.92
Limbic Lobe1.51 ± 0.66
Mesencephalon1.63 ± 0.66
Myelencephalon1.51 ± 0.65
Occipital Lobe1.51 ± 0.58
Parietal Lobe1.42 ± 0.6
Pontine Tegmentum1.52 ± 0.66
Striatum1.66 ± 0.67
Subthalamus1.56 ± 0.62
Temporal Lobe1.42 ± 0.64
Thalamus1.38 ± 0.59
White Matter2.04 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ptger3CBCerebellum3.71
4.92
Ptger3CTXCerebral cortex1.41
1.58
Ptger3HIPHippocampal region0.47
0.91
Ptger3HPFHippocampal formation0.45
0.8
Ptger3HYHypothalamus0.32
0.49
Ptger3LSXLateral septal complex0.94
2.31
Ptger3MBMidbrain0.84
0.98
Ptger3MYMedulla1.02
1.31
Ptger3OLFOlfactory bulb3.59
2.98
Ptger3PPons0.84
0.92
Ptger3PALPallidum0.32
0.28
Ptger3RHPRetrohippocampal region0.4
0.64
Ptger3sAMYStriatum-like amygdalar nuclei0.12
0.11
Ptger3STRStriatum0.32
0.5
Ptger3STRdStriatum dorsal region0.28
0.35
Ptger3STRvStriatum ventral region0.28
0.27
Ptger3THThalamus1.97
2.43
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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