AutismKB 2.0

Annotation Detail for SENP7


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Basic Information Top
Gene Symbol:SENP7 ( KIAA1707,MGC157730 )
Gene Full Name: SUMO1/sentrin specific peptidase 7
Band: 3q12.3
Quick LinksEntrez ID:57337; OMIM: 612846; Uniprot ID:SENP7_HUMAN; ENSEMBL ID: ENSG00000138468; HGNC ID: 30402
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus32 / 56401256
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor3 / 17290173
gastrointestinal tumor2 / 11936916
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor0 / 1363020 
kidney tumor3 / 6895943
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal89 / 336030726
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone4 / 7165555
bone marrow1 / 4880120
brain19 / 110098917
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus3 / 20209148
eye6 / 21105428
heart2 / 8962622
intestine1 / 2344724
kidney6 / 21177728
larynx0 / 241450 
liver3 / 20774314
lung5 / 33697414
lymph1 / 4427022
lymph node5 / 9161054
mammary gland1 / 1532716
mouth0 / 670520 
muscle5 / 10771546
nerve1 / 1576863
ovary2 / 10205119
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta3 / 28082510
prostate3 / 18934515
salivary gland1 / 2015549
skin2 / 2105749
spleen0 / 539520 
stomach2 / 9661920
testis6 / 33044218
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 220735_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.75
Adipocyte5.85
AdrenalCortex7.9
Adrenalgland5.4
Amygdala6.05
Appendix8
AtrioventricularNode8.35
BDCA4+_DentriticCells6.05
Bonemarrow6.45
BronchialEpithelialCells5.7
CD105+_Endothelial5.95
CD14+_Monocytes6.35
CD19+_BCells(neg._sel.)6.15
CD33+_Myeloid7.2
CD34+7.7
CD4+_Tcells18.35
CD56+_NKCells6.9
CD71+_EarlyErythroid5.8
CD8+_Tcells17.15
CardiacMyocytes9.35
Caudatenucleus5.4
Cerebellum4.95
CerebellumPeduncles7.4
CiliaryGanglion4.9
CingulateCortex6.35
Colorectaladenocarcinoma6
DorsalRootGanglion5.35
FetalThyroid5.95
Fetalbrain5.8
Fetalliver5.4
Fetallung4.6
GlobusPallidus5.5
Heart10.25
Hypothalamus6.45
Kidney5.4
Leukemia_chronicMyelogenousK-5625.4
Leukemia_promyelocytic-HL-605.3
Leukemialymphoblastic(MOLT-4)4.65
Liver8.9
Lung6.5
Lymphnode4.9
Lymphoma_burkitts(Daudi)8.15
Lymphoma_burkitts(Raji)9.15
MedullaOblongata5.4
OccipitalLobe5.35
OlfactoryBulb4.65
Ovary4.5
Pancreas5
PancreaticIslet6.5
ParietalLobe6.8
Pituitary6.95
Placenta5.95
Pons6.1
PrefrontalCortex7.2
Prostate6.8
Salivarygland5.15
SkeletalMuscle8.55
Skin6.05
SmoothMuscle6.75
Spinalcord6.35
SubthalamicNucleus5.75
SuperiorCervicalGanglion8.45
TemporalLobe5.7
Testis5.15
TestisGermCell4.8
TestisIntersitial5.25
TestisLeydigCell6.25
TestisSeminiferousTubule5.15
Thalamus6.25
Thymus4.45
Thyroid7.2
Tongue6.55
Tonsil6
Trachea5
TrigeminalGanglion6.95
Uterus4.9
UterusCorpus6.4
WholeBlood6.55
Wholebrain4.7
colon6.1
pineal_day7.5
pineal_night7.28
retina7.375
small_intestine5.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P6714
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.37 ± 0.5
Basal Forebrain4.3 ± 0.65
Basal Part of Pons4.49 ± 0.52
Cerebellar Cortex4.61 ± 0.27
Cerebellar Nuclei4.26 ± 0.66
Claustrum4.31 ± 0.78
Epithalamus4.5 ± 0.49
Frontal Lobe4.06 ± 0.51
Globus Pallidus4.37 ± 0.64
Hypothalamus4.17 ± 0.69
Insula3.92 ± 0.56
Limbic Lobe4.09 ± 0.55
Mesencephalon4.24 ± 0.55
Myelencephalon4.22 ± 0.55
Occipital Lobe4.63 ± 0.43
Parietal Lobe4.18 ± 0.64
Pontine Tegmentum4.04 ± 0.55
Striatum4.07 ± 0.56
Subthalamus3.83 ± 0.46
Temporal Lobe4.01 ± 0.59
Thalamus4.32 ± 0.53
White Matter5.28 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Senp7CBCerebellum0.58
1.14
Senp7CTXCerebral cortex1.14
1.07
Senp7HIPHippocampal region3.83
3.38
Senp7HPFHippocampal formation2.56
2.36
Senp7HYHypothalamus0.17
0.11
Senp7LSXLateral septal complex0.06
0
Senp7MBMidbrain0.4
0.88
Senp7MYMedulla0.83
1.04
Senp7OLFOlfactory bulb4.67
4.07
Senp7PPons0.39
0.64
Senp7PALPallidum0.04
0.03
Senp7RHPRetrohippocampal region0.43
0.97
Senp7sAMYStriatum-like amygdalar nuclei0.2
0.43
Senp7STRStriatum0.11
0.1
Senp7STRdStriatum dorsal region0.07
0.05
Senp7STRvStriatum ventral region0.17
0.1
Senp7THThalamus0.15
0.15
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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