AutismKB 2.0

Annotation Detail for PTGER4


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Basic Information Top
Gene Symbol:PTGER4 ( EP4,EP4R,MGC126583 )
Gene Full Name: prostaglandin E receptor 4 (subtype EP4)
Band: 5p13.1
Quick LinksEntrez ID:5734; OMIM: 601586; Uniprot ID:PE2R4_HUMAN; ENSEMBL ID: ENSG00000171522; HGNC ID: 9596
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst1 / 6231916
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult29 / 193912114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor3 / 26384511
glioma5 / 10688346
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia7 / 9584273
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal86 / 336030725
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood6 / 12347848
bone0 / 716550 
bone marrow0 / 488010 
brain9 / 11009898
cervix0 / 481710 
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine3 / 23447212
kidney3 / 21177714
larynx0 / 241450 
liver1 / 2077434
lung11 / 33697432
lymph1 / 4427022
lymph node18 / 91610196
mammary gland0 / 1532710 
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas6 / 21481227
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta1 / 2808253
prostate2 / 18934510
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach1 / 9661910
testis5 / 33044215
thymus4 / 8113149
thyroid1 / 4747321
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204896_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts3.55
Adipocyte2.75
AdrenalCortex2.9
Adrenalgland2.35
Amygdala3
Appendix2.8
AtrioventricularNode2.1
BDCA4+_DentriticCells3.5
Bonemarrow2.75
BronchialEpithelialCells2.8
CD105+_Endothelial2.85
CD14+_Monocytes3
CD19+_BCells(neg._sel.)3.05
CD33+_Myeloid19.4
CD34+3.6
CD4+_Tcells3.15
CD56+_NKCells34.3
CD71+_EarlyErythroid2.6
CD8+_Tcells2.8
CardiacMyocytes3.55
Caudatenucleus2.5
Cerebellum2.25
CerebellumPeduncles3.15
CiliaryGanglion1.95
CingulateCortex2.9
Colorectaladenocarcinoma2.8
DorsalRootGanglion2.1
FetalThyroid2.75
Fetalbrain2.8
Fetalliver2.4
Fetallung2.4
GlobusPallidus2.05
Heart3.55
Hypothalamus3.1
Kidney2.25
Leukemia_chronicMyelogenousK-5622.55
Leukemia_promyelocytic-HL-602.5
Leukemialymphoblastic(MOLT-4)2.25
Liver3.65
Lung3.15
Lymphnode2.45
Lymphoma_burkitts(Daudi)3.55
Lymphoma_burkitts(Raji)4.05
MedullaOblongata2.6
OccipitalLobe2.55
OlfactoryBulb2.25
Ovary1.85
Pancreas2.25
PancreaticIslet3
ParietalLobe2.9
Pituitary3.25
Placenta2.95
Pons2.65
PrefrontalCortex3.55
Prostate3.35
Salivarygland2.2
SkeletalMuscle3.2
Skin2.15
SmoothMuscle3.2
Spinalcord3
SubthalamicNucleus2.55
SuperiorCervicalGanglion3.15
TemporalLobe2.55
Testis2.4
TestisGermCell2.4
TestisIntersitial2.35
TestisLeydigCell2.8
TestisSeminiferousTubule2.45
Thalamus2.85
Thymus2.25
Thyroid3.55
Tongue2.75
Tonsil2.75
Trachea2.35
TrigeminalGanglion2.75
Uterus2.35
UterusCorpus2.5
WholeBlood3.15
Wholebrain2.45
colon2.85
pineal_day3.54
pineal_night3.46
retina3.45
small_intestine2.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P435394
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.9 ± 0.94
Basal Forebrain1.39 ± 0.36
Basal Part of Pons1.16 ± 0.5
Cerebellar Cortex1.18 ± 0.7
Cerebellar Nuclei1.61 ± 0.7
Claustrum2.17 ± 0.84
Epithalamus1.12 ± 0.7
Frontal Lobe1.2 ± 0.58
Globus Pallidus1.97 ± 0.35
Hypothalamus1.58 ± 0.61
Insula1.43 ± 0.63
Limbic Lobe1.39 ± 0.6
Mesencephalon1.49 ± 0.67
Myelencephalon1.44 ± 0.61
Occipital Lobe1.44 ± 0.63
Parietal Lobe1.31 ± 0.63
Pontine Tegmentum1.44 ± 0.74
Striatum1.5 ± 0.53
Subthalamus1.5 ± 0.6
Temporal Lobe1.42 ± 0.78
Thalamus1.35 ± 0.59
White Matter1.9 ± 0.24
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ptger4CBCerebellum47.21
29.96
Ptger4CTXCerebral cortex15.16
9.45
Ptger4HIPHippocampal region15.77
9.22
Ptger4HPFHippocampal formation19.32
12.06
Ptger4HYHypothalamus13.96
8.74
Ptger4LSXLateral septal complex2.83
1.57
Ptger4MBMidbrain14.49
9.73
Ptger4MYMedulla32.6
25.07
Ptger4OLFOlfactory bulb32.44
18.34
Ptger4PPons29.37
21.73
Ptger4PALPallidum8.21
5.48
Ptger4RHPRetrohippocampal region24.17
15.36
Ptger4sAMYStriatum-like amygdalar nuclei20.58
11.72
Ptger4STRStriatum8.06
4.5
Ptger4STRdStriatum dorsal region5.43
2.98
Ptger4STRvStriatum ventral region16.97
8.94
Ptger4THThalamus11.6
6.68
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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