AutismKB 2.0

Annotation Detail for PTGFRN


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Basic Information Top
Gene Symbol:PTGFRN ( CD315,CD9P-1,EWI-F,FLJ11001,FPRP,KIAA1436,SMAP-6 )
Gene Full Name: prostaglandin F2 receptor negative regulator
Band: 1p13.1
Quick LinksEntrez ID:5738; OMIM: 601204; Uniprot ID:FPRP_HUMAN; ENSEMBL ID: ENSG00000134247; HGNC ID: 9601
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body12 / 70761169
blastocyst2 / 6231932
fetus25 / 56401244
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult419 / 1939121216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma5 / 17475286
breast (mammary gland) tumor1 / 9417810
cervical tumor2 / 3436658
chondrosarcoma7 / 8282384
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor293 / 1193692454
germ cell tumor18 / 26384568
glioma6 / 10688356
head and neck tumor11 / 13630280
kidney tumor3 / 6895943
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal154 / 336030745
ovarian tumor6 / 7668278
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor6 / 12494948
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood0 / 1234780 
bone3 / 7165541
bone marrow0 / 488010 
brain22 / 110098919
cervix2 / 4817141
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue17 / 21572278
esophagus0 / 202090 
eye8 / 21105437
heart15 / 89626167
intestine21 / 23447289
kidney8 / 21177737
larynx0 / 241450 
liver4 / 20774319
lung10 / 33697429
lymph0 / 442700 
lymph node0 / 916100 
mammary gland12 / 15327178
mouth9 / 67052134
muscle7 / 10771564
nerve0 / 157680 
ovary6 / 10205158
pancreas5 / 21481223
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta18 / 28082564
prostate14 / 18934573
salivary gland0 / 201550 
skin19 / 21057490
spleen0 / 539520 
stomach291 / 966193011
testis11 / 33044233
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus16 / 23287868
vascular3 / 5178057
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P114968
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.7 ± 0.8
Basal Forebrain3.56 ± 0.27
Basal Part of Pons3.37 ± 0.36
Cerebellar Cortex3.2 ± 0.67
Cerebellar Nuclei3.91 ± 0.65
Claustrum3.79 ± 0.67
Epithalamus3.18 ± 0.75
Frontal Lobe3.71 ± 0.63
Globus Pallidus3.63 ± 0.69
Hypothalamus3.19 ± 0.44
Insula3.49 ± 0.54
Limbic Lobe3.67 ± 0.68
Mesencephalon3.81 ± 0.69
Myelencephalon3.7 ± 0.71
Occipital Lobe3.42 ± 0.83
Parietal Lobe3.65 ± 0.72
Pontine Tegmentum3.48 ± 0.58
Striatum3.65 ± 0.73
Subthalamus4.43 ± 0.68
Temporal Lobe3.69 ± 0.59
Thalamus3.55 ± 0.57
White Matter3.38 ± 0.72
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
PtgfrnCBCerebellum100
100
PtgfrnCTXCerebral cortex100
100
PtgfrnHIPHippocampal region100
100
PtgfrnHPFHippocampal formation100
100
PtgfrnHYHypothalamus100
100
PtgfrnLSXLateral septal complex100
100
PtgfrnMBMidbrain100
100
PtgfrnMYMedulla100
100
PtgfrnOLFOlfactory bulb100
100
PtgfrnPPons100
100
PtgfrnPALPallidum100
100
PtgfrnRHPRetrohippocampal region100
100
PtgfrnsAMYStriatum-like amygdalar nuclei100
100
PtgfrnSTRStriatum100
100
PtgfrnSTRdStriatum dorsal region100
100
PtgfrnSTRvStriatum ventral region100
100
PtgfrnTHThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00039520 19 554 572 ARQPKPFFAAGNTFEMTCK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018