AutismKB 2.0

Annotation Detail for SCYL1


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Basic Information Top
Gene Symbol:SCYL1 ( GKLP,MGC78454,NKTL,NTKL,P105,TAPK,TEIF,TRAP )
Gene Full Name: SCY1-like 1 (S. cerevisiae)
Band: 11q13.1
Quick LinksEntrez ID:57410; OMIM: 607982; Uniprot ID:NTKL_HUMAN; ENSEMBL ID: ENSG00000142186; HGNC ID: 14372
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst7 / 62319112
fetus31 / 56401254
neonate1 / 3109732
infant1 / 2362042
juvenile0 / 555560 
adult160 / 193912182
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor16 / 114246140
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor17 / 26384564
glioma7 / 10688365
head and neck tumor2 / 13630214
kidney tumor10 / 68959145
leukemia17 / 95842177
liver tumor10 / 96359103
lung tumor12 / 103127116
lymphoma7 / 7175597
non-neoplasia6 / 9725061
normal181 / 336030753
ovarian tumor5 / 7668265
pancreatic tumor13 / 104616124
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer14 / 102680136
retinoblastoma0 / 463560 
skin tumor33 / 124949264
soft tissue/muscle tissue tumor12 / 12519195
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland4 / 33197120
ascites1 / 4001524
bladder0 / 297570 
blood2 / 12347816
bone8 / 71655111
bone marrow16 / 48801327
brain37 / 110098933
cervix2 / 4817141
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye21 / 21105499
heart7 / 8962678
intestine24 / 234472102
kidney15 / 21177770
larynx0 / 241450 
liver15 / 20774372
lung33 / 33697497
lymph2 / 4427045
lymph node23 / 91610251
mammary gland12 / 15327178
mouth0 / 670520 
muscle9 / 10771583
nerve0 / 157680 
ovary6 / 10205158
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta22 / 28082578
prostate23 / 189345121
salivary gland0 / 201550 
skin45 / 210574213
spleen1 / 5395218
stomach5 / 9661951
testis17 / 33044251
thymus3 / 8113136
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord1 / 1368073
uterus16 / 23287868
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P75470
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.02 ± 0.33
Basal Forebrain5.7 ± 0.37
Basal Part of Pons6.1 ± 0.29
Cerebellar Cortex5.87 ± 0.41
Cerebellar Nuclei5.69 ± 0.37
Claustrum5.71 ± 0.55
Epithalamus5.62 ± 0.71
Frontal Lobe5.94 ± 0.39
Globus Pallidus5.16 ± 0.28
Hypothalamus5.53 ± 0.52
Insula5.83 ± 0.24
Limbic Lobe5.98 ± 0.33
Mesencephalon5.64 ± 0.49
Myelencephalon5.76 ± 0.45
Occipital Lobe5.58 ± 0.36
Parietal Lobe5.82 ± 0.38
Pontine Tegmentum5.76 ± 0.38
Striatum5.34 ± 0.35
Subthalamus5.6 ± 0.18
Temporal Lobe5.91 ± 0.33
Thalamus5.72 ± 0.38
White Matter5 ± 0.36
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Scyl1CBCerebellum52.94
69.99
Scyl1CTXCerebral cortex100
93.98
Scyl1HIPHippocampal region59.05
82.85
Scyl1HPFHippocampal formation78.68
93.64
Scyl1HYHypothalamus69.82
62.19
Scyl1LSXLateral septal complex48.2
38.49
Scyl1MBMidbrain73.09
70.59
Scyl1MYMedulla81.43
100
Scyl1OLFOlfactory bulb100
100
Scyl1PPons76.92
91.14
Scyl1PALPallidum59.88
64.83
Scyl1RHPRetrohippocampal region100
100
Scyl1sAMYStriatum-like amygdalar nuclei100
89.35
Scyl1STRStriatum81.26
64.84
Scyl1STRdStriatum dorsal region81.21
63.32
Scyl1STRvStriatum ventral region88.41
69.51
Scyl1THThalamus87.74
83.45
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00024449 17 88 104 CLHVVTEAVTPLGIYLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018