AutismKB 2.0

Annotation Detail for NDRG3


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Basic Information Top
Gene Symbol:NDRG3 ( FLJ13556 )
Gene Full Name: NDRG family member 3
Band: 20q11.23
Quick LinksEntrez ID:57446; OMIM: 605273; Uniprot ID:NDRG3_HUMAN; ENSEMBL ID: ENSG00000101079; HGNC ID: 14462
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus24 / 56401242
neonate1 / 3109732
infant4 / 23620169
juvenile1 / 5555617
adult103 / 193912153
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor14 / 94178148
cervical tumor3 / 3436687
chondrosarcoma6 / 8282372
colorectal tumor6 / 11424652
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor20 / 26384575
glioma5 / 10688346
head and neck tumor6 / 13630244
kidney tumor6 / 6895987
leukemia4 / 9584241
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal160 / 336030747
ovarian tumor2 / 7668226
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer6 / 10268058
retinoblastoma1 / 4635621
skin tumor4 / 12494932
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone4 / 7165555
bone marrow1 / 4880120
brain91 / 110098982
cervix3 / 4817162
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye20 / 21105494
heart1 / 8962611
intestine9 / 23447238
kidney6 / 21177728
larynx2 / 2414582
liver2 / 2077439
lung8 / 33697423
lymph0 / 442700 
lymph node0 / 916100 
mammary gland15 / 15327197
mouth3 / 6705244
muscle2 / 10771518
nerve0 / 157680 
ovary2 / 10205119
pancreas12 / 21481255
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta2 / 2808257
prostate15 / 18934579
salivary gland0 / 201550 
skin5 / 21057423
spleen1 / 5395218
stomach3 / 9661931
testis30 / 33044290
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus2 / 2328788
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217286_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts135.6
Adipocyte76.7
AdrenalCortex126.65
Adrenalgland137.6
Amygdala700.7
Appendix70.8
AtrioventricularNode24.95
BDCA4+_DentriticCells201.95
Bonemarrow28.3
BronchialEpithelialCells99.75
CD105+_Endothelial44.95
CD14+_Monocytes331.9
CD19+_BCells(neg._sel.)364.75
CD33+_Myeloid218.75
CD34+90.7
CD4+_Tcells227.85
CD56+_NKCells351.85
CD71+_EarlyErythroid5.55
CD8+_Tcells179.1
CardiacMyocytes42.6
Caudatenucleus596.8
Cerebellum969.75
CerebellumPeduncles1189.3
CiliaryGanglion49.05
CingulateCortex959.3
Colorectaladenocarcinoma70.6
DorsalRootGanglion65.15
FetalThyroid114.15
Fetalbrain622.65
Fetalliver16.7
Fetallung52.1
GlobusPallidus523
Heart57.75
Hypothalamus1136.85
Kidney70.1
Leukemia_chronicMyelogenousK-56244.5
Leukemia_promyelocytic-HL-60143.05
Leukemialymphoblastic(MOLT-4)139.5
Liver9.05
Lung155.4
Lymphnode76.95
Lymphoma_burkitts(Daudi)74.4
Lymphoma_burkitts(Raji)251.35
MedullaOblongata806.05
OccipitalLobe749.05
OlfactoryBulb153.65
Ovary25.75
Pancreas60.5
PancreaticIslet77.7
ParietalLobe931.6
Pituitary227.15
Placenta58.55
Pons637.85
PrefrontalCortex1061.05
Prostate660.4
Salivarygland51.4
SkeletalMuscle91.65
Skin41.5
SmoothMuscle113.8
Spinalcord526.95
SubthalamicNucleus863.8
SuperiorCervicalGanglion53.75
TemporalLobe742.2
Testis54.85
TestisGermCell82.3
TestisIntersitial39.5
TestisLeydigCell34.05
TestisSeminiferousTubule55.55
Thalamus1022.55
Thymus98.85
Thyroid50.85
Tongue129.1
Tonsil53.05
Trachea85.8
TrigeminalGanglion58.7
Uterus90.4
UterusCorpus50.55
WholeBlood213.15
Wholebrain1103
colon70.85
pineal_day2449.8
pineal_night2263.22
retina279.75
small_intestine76.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_12408_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.51 ± 0.42
Basal Forebrain6.11 ± 0.19
Basal Part of Pons7.09 ± 0.17
Cerebellar Cortex6.84 ± 0.15
Cerebellar Nuclei6.43 ± 0.62
Claustrum6.37 ± 0.41
Epithalamus5.59 ± 0.41
Frontal Lobe6.46 ± 0.47
Globus Pallidus5.76 ± 0.27
Hypothalamus5.91 ± 0.53
Insula6.19 ± 0.3
Limbic Lobe6.59 ± 0.48
Mesencephalon6.13 ± 0.48
Myelencephalon6.38 ± 0.53
Occipital Lobe6.88 ± 0.39
Parietal Lobe6.56 ± 0.39
Pontine Tegmentum6.42 ± 0.33
Striatum5.79 ± 0.29
Subthalamus6.31 ± 0.8
Temporal Lobe6.36 ± 0.4
Thalamus6.55 ± 0.36
White Matter5.34 ± 0.27
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ndrg3CBCerebellum100
100
Ndrg3CTXCerebral cortex100
100
Ndrg3HIPHippocampal region100
100
Ndrg3HPFHippocampal formation100
100
Ndrg3HYHypothalamus95.43
83.28
Ndrg3LSXLateral septal complex70.11
54.32
Ndrg3MBMidbrain93.42
95.32
Ndrg3MYMedulla94.8
100
Ndrg3OLFOlfactory bulb100
100
Ndrg3PPons93.99
100
Ndrg3PALPallidum85.46
92.71
Ndrg3RHPRetrohippocampal region100
100
Ndrg3sAMYStriatum-like amygdalar nuclei100
94.91
Ndrg3STRStriatum59.9
48.18
Ndrg3STRdStriatum dorsal region38.79
31.69
Ndrg3STRvStriatum ventral region100
71.93
Ndrg3THThalamus83.28
86.89
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NDRG3_HUMAN_1 19 1 19 MDELQDVQLTEIKPLLNDK PRIDE
NDRG3_HUMAN_1 23 1 23 MDELQDVQLTEIKPLLNDKNGTR PRIDE
PAp00040535 17 52 68 GNRPVILTYHDIGLNHK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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