AutismKB 2.0

Annotation Detail for NDRG2


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Basic Information Top
Gene Symbol:NDRG2 ( DKFZp781G1938,FLJ25522,KIAA1248,SYLD )
Gene Full Name: NDRG family member 2
Band: 14q11.2
Quick LinksEntrez ID:57447; OMIM: 605272; Uniprot ID:NDRG2_HUMAN; ENSEMBL ID: ENSG00000165795; HGNC ID: 14460
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst2 / 6231932
fetus128 / 564012226
neonate2 / 3109764
infant4 / 23620169
juvenile12 / 55556215
adult512 / 1939121264
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor11 / 94178116
cervical tumor7 / 34366203
chondrosarcoma4 / 8282348
colorectal tumor6 / 11424652
esophageal tumor4 / 17290231
gastrointestinal tumor15 / 119369125
germ cell tumor12 / 26384545
glioma69 / 106883645
head and neck tumor11 / 13630280
kidney tumor77 / 689591116
leukemia6 / 9584262
liver tumor11 / 96359114
lung tumor10 / 10312796
lymphoma0 / 717550 
non-neoplasia154 / 972501583
normal1918 / 3360307570
ovarian tumor3 / 7668239
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS14 / 125680111
prostate cancer4 / 10268038
retinoblastoma2 / 4635643
skin tumor1 / 1249498
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue7 / 13106534
adrenal gland56 / 331971686
ascites3 / 4001574
bladder2 / 2975767
blood7 / 12347856
bone2 / 7165527
bone marrow1 / 4880120
brain1570 / 11009891425
cervix10 / 48171207
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus4 / 20209197
eye33 / 211054156
heart94 / 896261048
intestine50 / 234472213
kidney107 / 211777505
larynx2 / 2414582
liver70 / 207743336
lung44 / 336974130
lymph0 / 442700 
lymph node1 / 9161010
mammary gland32 / 153271208
mouth17 / 67052253
muscle98 / 107715909
nerve15 / 15768951
ovary7 / 10205168
pancreas4 / 21481218
parathyroid10 / 20539486
pharynx6 / 41328145
pituitary gland0 / 165850 
placenta15 / 28082553
prostate47 / 189345248
salivary gland25 / 201551240
skin8 / 21057437
spleen51 / 53952945
stomach24 / 96619248
testis12 / 33044236
thymus14 / 81131172
thyroid6 / 47473126
tonsil0 / 169990 
trachea52 / 52413992
umbilical cord0 / 136800 
uterus56 / 232878240
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206453_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts20.95
Adipocyte20.9
AdrenalCortex232.8
Adrenalgland226.9
Amygdala1222.4
Appendix250.75
AtrioventricularNode154.65
BDCA4+_DentriticCells131.7
Bonemarrow20.85
BronchialEpithelialCells17.2
CD105+_Endothelial38.45
CD14+_Monocytes53.65
CD19+_BCells(neg._sel.)33.6
CD33+_Myeloid76.2
CD34+45.65
CD4+_Tcells54.3
CD56+_NKCells39.65
CD71+_EarlyErythroid19.9
CD8+_Tcells48.1
CardiacMyocytes26.95
Caudatenucleus1042.7
Cerebellum1943.85
CerebellumPeduncles1695.15
CiliaryGanglion81.4
CingulateCortex1431.3
Colorectaladenocarcinoma28.55
DorsalRootGanglion193.65
FetalThyroid129.65
Fetalbrain260.75
Fetalliver160.65
Fetallung119.6
GlobusPallidus656.6
Heart505.35
Hypothalamus2983.25
Kidney71.75
Leukemia_chronicMyelogenousK-56243.05
Leukemia_promyelocytic-HL-6018.7
Leukemialymphoblastic(MOLT-4)25.1
Liver853.9
Lung241.65
Lymphnode67.1
Lymphoma_burkitts(Daudi)43.65
Lymphoma_burkitts(Raji)53.3
MedullaOblongata1063.15
OccipitalLobe1223.2
OlfactoryBulb971.5
Ovary234.15
Pancreas68.2
PancreaticIslet100.95
ParietalLobe1053.05
Pituitary127.6
Placenta61.6
Pons631.2
PrefrontalCortex3052.25
Prostate394.85
Salivarygland394.7
SkeletalMuscle366.5
Skin67.9
SmoothMuscle23.7
Spinalcord1324.4
SubthalamicNucleus785.65
SuperiorCervicalGanglion92
TemporalLobe1017.1
Testis31.65
TestisGermCell42.25
TestisIntersitial59.1
TestisLeydigCell53.45
TestisSeminiferousTubule36
Thalamus958.7
Thymus92.9
Thyroid210.65
Tongue341.4
Tonsil72.2
Trachea365.85
TrigeminalGanglion199.6
Uterus272.35
UterusCorpus82.4
WholeBlood18.65
Wholebrain2578.8
colon117.25
pineal_day615.72
pineal_night314.96
retina816.425
small_intestine68.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P244800
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala11.48 ± 0.44
Basal Forebrain11.63 ± 0.29
Basal Part of Pons10.66 ± 0.34
Cerebellar Cortex11.09 ± 0.39
Cerebellar Nuclei11.36 ± 0.48
Claustrum11.32 ± 0.38
Epithalamus11.43 ± 0.31
Frontal Lobe11.19 ± 0.47
Globus Pallidus12.89 ± 0.34
Hypothalamus11.42 ± 0.3
Insula11.16 ± 0.44
Limbic Lobe11.11 ± 0.6
Mesencephalon11.65 ± 0.46
Myelencephalon11.46 ± 0.51
Occipital Lobe11.55 ± 0.49
Parietal Lobe11.45 ± 0.48
Pontine Tegmentum11.52 ± 0.36
Striatum11.57 ± 0.57
Subthalamus11.28 ± 0.27
Temporal Lobe11.24 ± 0.41
Thalamus11.77 ± 0.31
White Matter12.2 ± 0.48
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ndrg2CBCerebellum90.4
100
Ndrg2CTXCerebral cortex95.75
79.05
Ndrg2HIPHippocampal region100
91.92
Ndrg2HPFHippocampal formation100
95.99
Ndrg2HYHypothalamus100
95.15
Ndrg2LSXLateral septal complex89.86
74.67
Ndrg2MBMidbrain100
97.18
Ndrg2MYMedulla100
100
Ndrg2OLFOlfactory bulb100
99.94
Ndrg2PPons100
99.57
Ndrg2PALPallidum100
92.88
Ndrg2RHPRetrohippocampal region100
100
Ndrg2sAMYStriatum-like amygdalar nuclei97.48
83.07
Ndrg2STRStriatum83.51
72.22
Ndrg2STRdStriatum dorsal region73.85
63.27
Ndrg2STRvStriatum ventral region100
78.6
Ndrg2THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00024487 23 255 277 CPVMLVVGDQAPHEDAVVECNSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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