AutismKB 2.0

Annotation Detail for BIRC6


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Basic Information Top
Gene Symbol:BIRC6 ( APOLLON,BRUCE,FLJ13726,FLJ13786,KIAA1289 )
Gene Full Name: baculoviral IAP repeat-containing 6
Band: 2p22.3
Quick LinksEntrez ID:57448; OMIM: 605638; Uniprot ID:BIRC6_HUMAN; ENSEMBL ID: ENSG00000115760; HGNC ID: 13516
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst8 / 62319128
fetus60 / 564012106
neonate1 / 3109732
infant1 / 2362042
juvenile2 / 5555635
adult224 / 1939121115
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor15 / 94178159
cervical tumor2 / 3436658
chondrosarcoma5 / 8282360
colorectal tumor12 / 114246105
esophageal tumor2 / 17290115
gastrointestinal tumor4 / 11936933
germ cell tumor13 / 26384549
glioma5 / 10688346
head and neck tumor24 / 136302176
kidney tumor3 / 6895943
leukemia4 / 9584241
liver tumor7 / 9635972
lung tumor7 / 10312767
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal268 / 336030779
ovarian tumor2 / 7668226
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer4 / 10268038
retinoblastoma4 / 4635686
skin tumor7 / 12494956
soft tissue/muscle tissue tumor46 / 125191367
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue3 / 13106228
adrenal gland2 / 3319760
ascites1 / 4001524
bladder1 / 2975733
blood4 / 12347832
bone3 / 7165541
bone marrow1 / 4880120
brain64 / 110098958
cervix2 / 4817141
connective tissue47 / 149255314
ear1 / 1621261
embryonic tissue17 / 21572278
esophagus2 / 2020998
eye11 / 21105452
heart6 / 8962666
intestine14 / 23447259
kidney7 / 21177733
larynx4 / 24145165
liver14 / 20774367
lung16 / 33697447
lymph0 / 442700 
lymph node11 / 91610120
mammary gland33 / 153271215
mouth10 / 67052149
muscle8 / 10771574
nerve0 / 157680 
ovary2 / 10205119
pancreas19 / 21481288
parathyroid0 / 205390 
pharynx7 / 41328169
pituitary gland2 / 16585120
placenta23 / 28082581
prostate6 / 18934531
salivary gland0 / 201550 
skin22 / 210574104
spleen0 / 539520 
stomach4 / 9661941
testis27 / 33044281
thymus9 / 81131110
thyroid10 / 47473210
tonsil1 / 1699958
trachea5 / 5241395
umbilical cord0 / 136800 
uterus25 / 232878107
vascular4 / 5178077
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P109315
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.99 ± 0.68
Basal Forebrain2.8 ± 0.81
Basal Part of Pons2.49 ± 0.6
Cerebellar Cortex2.84 ± 0.82
Cerebellar Nuclei3.02 ± 0.62
Claustrum3.39 ± 1.08
Epithalamus2.35 ± 0.74
Frontal Lobe2.82 ± 0.68
Globus Pallidus3.05 ± 0.55
Hypothalamus2.52 ± 0.68
Insula2.07 ± 0.78
Limbic Lobe2.78 ± 0.68
Mesencephalon2.83 ± 0.74
Myelencephalon2.85 ± 0.73
Occipital Lobe2.98 ± 0.87
Parietal Lobe2.81 ± 0.68
Pontine Tegmentum2.89 ± 0.72
Striatum2.97 ± 0.76
Subthalamus2.98 ± 0.64
Temporal Lobe2.7 ± 0.73
Thalamus2.94 ± 0.61
White Matter3.25 ± 0.65
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Birc6CBCerebellum33.51
44.89
Birc6CTXCerebral cortex100
95.77
Birc6HIPHippocampal region48.61
91.41
Birc6HPFHippocampal formation63.71
85
Birc6HYHypothalamus68.5
55.49
Birc6LSXLateral septal complex59.81
48.7
Birc6MBMidbrain63.5
59.86
Birc6MYMedulla57.94
68.67
Birc6OLFOlfactory bulb75.13
67.93
Birc6PPons59.99
65.48
Birc6PALPallidum57.96
53.3
Birc6RHPRetrohippocampal region92.37
81.97
Birc6sAMYStriatum-like amygdalar nuclei63
50.14
Birc6STRStriatum52.55
40.15
Birc6STRdStriatum dorsal region50.01
38.75
Birc6STRvStriatum ventral region54.55
37.44
Birc6THThalamus71.99
65.48
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00068090 28 360 387 GEHTQNVPLSVTLATSPAQFPCTDGTDR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018