AutismKB 2.0

Annotation Detail for REXO1


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Basic Information Top
Gene Symbol:REXO1 ( ELOABP1,EloA-BP1,KIAA1138,REX1,TCEB3BP1 )
Gene Full Name: REX1, RNA exonuclease 1 homolog (S. cerevisiae)
Band: 19p13.3
Quick LinksEntrez ID:57455; OMIM: 609614; Uniprot ID:REXO1_HUMAN; ENSEMBL ID: ENSG00000079313; HGNC ID: 24616
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst4 / 6231964
fetus6 / 56401210
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult43 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma2 / 17475114
breast (mammary gland) tumor0 / 941780 
cervical tumor1 / 3436629
chondrosarcoma3 / 8282336
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor9 / 26384534
glioma8 / 10688374
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia6 / 9584262
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma2 / 7175527
non-neoplasia1 / 9725010
normal98 / 336030729
ovarian tumor2 / 7668226
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor5 / 12494940
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder3 / 29757100
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain20 / 110098918
cervix2 / 4817141
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye12 / 21105456
heart0 / 896260 
intestine5 / 23447221
kidney4 / 21177718
larynx3 / 24145124
liver1 / 2077434
lung5 / 33697414
lymph1 / 4427022
lymph node8 / 9161087
mammary gland1 / 1532716
mouth1 / 6705214
muscle1 / 1077159
nerve2 / 15768126
ovary6 / 10205158
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta13 / 28082546
prostate1 / 1893455
salivary gland0 / 201550 
skin5 / 21057423
spleen3 / 5395255
stomach0 / 966190 
testis25 / 33044275
thymus0 / 811310 
thyroid0 / 474730 
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1232_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.29 ± 0.89
Basal Forebrain3.72 ± 0.21
Basal Part of Pons3.89 ± 0.5
Cerebellar Cortex3.47 ± 0.57
Cerebellar Nuclei3.51 ± 0.55
Claustrum4.91 ± 0.86
Epithalamus3.33 ± 0.65
Frontal Lobe3.73 ± 0.66
Globus Pallidus3.56 ± 0.68
Hypothalamus3.1 ± 0.66
Insula3.68 ± 0.67
Limbic Lobe4.23 ± 0.78
Mesencephalon3.92 ± 0.7
Myelencephalon4.04 ± 0.73
Occipital Lobe4.6 ± 0.8
Parietal Lobe4.06 ± 0.66
Pontine Tegmentum3.98 ± 0.79
Striatum4.98 ± 0.52
Subthalamus3.59 ± 1.08
Temporal Lobe3.93 ± 0.6
Thalamus4.13 ± 0.61
White Matter3.25 ± 0.7
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Rexo1CBCerebellum28.14
30.57
Rexo1CTXCerebral cortex61.35
47.19
Rexo1HIPHippocampal region35.3
45.7
Rexo1HPFHippocampal formation35.19
37
Rexo1HYHypothalamus11.68
8.89
Rexo1LSXLateral septal complex42.87
33.42
Rexo1MBMidbrain18.63
15.95
Rexo1MYMedulla21.86
21.55
Rexo1OLFOlfactory bulb61.43
50.13
Rexo1PPons18.03
17.07
Rexo1PALPallidum25.53
21.19
Rexo1RHPRetrohippocampal region34.97
26.35
Rexo1sAMYStriatum-like amygdalar nuclei17.47
11.54
Rexo1STRStriatum37.97
26.6
Rexo1STRdStriatum dorsal region36.14
25.17
Rexo1STRvStriatum ventral region47.27
32.03
Rexo1THThalamus26.29
21.43
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018