AutismKB 2.0

Annotation Detail for SHROOM4


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Basic Information Top
Gene Symbol:SHROOM4 ( KIAA1202,SHAP )
Gene Full Name: shroom family member 4
Band: Xp11.22
Quick LinksEntrez ID:57477; OMIM: 300579; Uniprot ID:SHRM4_HUMAN; ENSEMBL ID: ENSG00000158352; HGNC ID: 29215
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus2 / 5640123
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult19 / 19391219
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal22 / 33603076
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain8 / 11009897
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine4 / 23447217
kidney1 / 2117774
larynx0 / 241450 
liver2 / 2077439
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas4 / 21481218
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta1 / 2808253
prostate2 / 18934510
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach2 / 9661920
testis0 / 3304420 
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular2 / 5178038
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11830_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.75 ± 0.93
Basal Forebrain3.19 ± 0.94
Basal Part of Pons2.89 ± 0.54
Cerebellar Cortex2.49 ± 0.78
Cerebellar Nuclei3.38 ± 0.71
Claustrum3.06 ± 0.71
Epithalamus2.43 ± 0.77
Frontal Lobe2.98 ± 0.81
Globus Pallidus4.33 ± 0.49
Hypothalamus2.53 ± 0.69
Insula2.39 ± 0.74
Limbic Lobe2.95 ± 0.87
Mesencephalon2.94 ± 0.8
Myelencephalon3.1 ± 0.81
Occipital Lobe3.14 ± 0.92
Parietal Lobe3.05 ± 0.93
Pontine Tegmentum3.1 ± 0.87
Striatum3.72 ± 0.73
Subthalamus2.68 ± 0.52
Temporal Lobe2.83 ± 0.82
Thalamus3.46 ± 0.68
White Matter5.62 ± 0.1
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Shroom4CBCerebellum1.44
1.94
Shroom4CTXCerebral cortex0.54
0.62
Shroom4HIPHippocampal region0.81
1.03
Shroom4HPFHippocampal formation0.81
0.91
Shroom4HYHypothalamus0.14
0.16
Shroom4LSXLateral septal complex0.18
0.14
Shroom4MBMidbrain1.33
1.35
Shroom4MYMedulla1.67
2.18
Shroom4OLFOlfactory bulb2.14
2.83
Shroom4PPons1.29
1.32
Shroom4PALPallidum0.16
0.12
Shroom4RHPRetrohippocampal region0.71
0.67
Shroom4sAMYStriatum-like amygdalar nuclei0.21
0.23
Shroom4STRStriatum0.56
0.65
Shroom4STRdStriatum dorsal region0.73
0.91
Shroom4STRvStriatum ventral region0.37
0.28
Shroom4THThalamus1
0.82
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018