Annotation Detail for PLEKHG1
Basic Information Top
| Gene Symbol: | PLEKHG1 ( ARHGEF41,FLJ31738,KIAA1209 ) |
|---|---|
| Gene Full Name: | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 |
| Band: | 6q25.1 |
| Quick Links | Entrez ID:57480; OMIM: NA; Uniprot ID:PKHG1_HUMAN; ENSEMBL ID: ENSG00000120278; HGNC ID: 20884 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.189781
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 2 / 62319 | 32 | |
| fetus | 21 / 564012 | 37 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 34 / 1939121 | 17 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 3 / 119369 | 25 | |
| germ cell tumor | 6 / 263845 | 22 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 2 / 95842 | 20 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 3 / 71755 | 41 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 82 / 3360307 | 24 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 1 / 104616 | 9 |  |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 4 / 90257 | 44 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 1 / 13106 | 76 |  |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 3 / 40015 | 74 | |
| bladder | 0 / 29757 | 0 | |
| blood | 2 / 123478 | 16 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 18 / 1100989 | 16 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 1 / 16212 | 61 | |
| embryonic tissue | 5 / 215722 | 23 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 1 / 211054 | 4 | |
| heart | 1 / 89626 | 11 | |
| intestine | 0 / 234472 | 0 | |
| kidney | 4 / 211777 | 18 | |
| larynx | 1 / 24145 | 41 | |
| liver | 1 / 207743 | 4 | |
| lung | 11 / 336974 | 32 | |
| lymph | 2 / 44270 | 45 | |
| lymph node | 10 / 91610 | 109 | |
| mammary gland | 2 / 153271 | 13 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 1 / 102051 | 9 | |
| pancreas | 2 / 214812 | 9 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 10 / 280825 | 35 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 1 / 210574 | 4 | |
| spleen | 7 / 53952 | 129 | |
| stomach | 2 / 96619 | 20 | |
| testis | 6 / 330442 | 18 | |
| thymus | 4 / 81131 | 49 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 1 / 16999 | 58 | |
| trachea | 2 / 52413 | 38 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 4 / 232878 | 17 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_11305_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 1.87 ± 1 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 1.34 ± 0.24 | |
| Basal Part of Pons | 1.61 ± 0.46 | |
| Cerebellar Cortex | 1.21 ± 0.62 | |
| Cerebellar Nuclei | 1.84 ± 0.69 | |
| Claustrum | 2.12 ± 0.73 | |
| Epithalamus | 1.34 ± 0.76 | |
| Frontal Lobe | 1.42 ± 0.66 | |
| Globus Pallidus | 2.5 ± 0.62 | |
| Hypothalamus | 1.55 ± 0.78 | |
| Insula | 1.29 ± 0.44 | |
| Limbic Lobe | 1.47 ± 0.72 | |
| Mesencephalon | 1.74 ± 0.82 | |
| Myelencephalon | 1.56 ± 0.69 | |
| Occipital Lobe | 1.89 ± 0.68 | |
| Parietal Lobe | 1.63 ± 0.93 | |
| Pontine Tegmentum | 1.65 ± 0.78 | |
| Striatum | 1.7 ± 0.57 | |
| Subthalamus | 1.54 ± 0.64 | |
| Temporal Lobe | 1.46 ± 0.65 | |
| Thalamus | 1.79 ± 0.51 | |
| White Matter | 3.46 ± 0.26 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Plekhg1 | CB | Cerebellum | 2.73 | |
| 2.86 | | |||
| Plekhg1 | CTX | Cerebral cortex | 1.61 | |
| 1.45 | | |||
| Plekhg1 | HIP | Hippocampal region | 7.04 | |
| 8.72 | | |||
| Plekhg1 | HPF | Hippocampal formation | 4.73 | |
| 4.93 | | |||
| Plekhg1 | HY | Hypothalamus | 5.61 | |
| 8.55 | | |||
| Plekhg1 | LSX | Lateral septal complex | 1.27 | |
| 0.92 | | |||
| Plekhg1 | MB | Midbrain | 3.25 | |
| 3.46 | | |||
| Plekhg1 | MY | Medulla | 2.5 | |
| 2.24 | | |||
| Plekhg1 | OLF | Olfactory bulb | 2.39 | |
| 2.34 | | |||
| Plekhg1 | P | Pons | 2.08 | |
| 1.83 | | |||
| Plekhg1 | PAL | Pallidum | 1.19 | |
| 0.81 | | |||
| Plekhg1 | RHP | Retrohippocampal region | 2.49 | |
| 1.65 | | |||
| Plekhg1 | sAMY | Striatum-like amygdalar nuclei | 1.07 | |
| 0.66 | | |||
| Plekhg1 | STR | Striatum | 1.33 | |
| 0.87 | | |||
| Plekhg1 | STRd | Striatum dorsal region | 1.31 | |
| 0.92 | | |||
| Plekhg1 | STRv | Striatum ventral region | 1.51 | |
| 0.8 | | |||
| Plekhg1 | TH | Thalamus | 89.16 | |
| 100 | |