Annotation Detail for MKL2
Basic Information Top
Gene Symbol: | MKL2 ( DKFZp686J1745,FLJ31823,FLJ45623,MRTF-B,NPD001 ) |
---|---|
Gene Full Name: | MKL/myocardin-like 2 |
Band: | 16p13.12 |
Quick Links | Entrez ID:57496; OMIM: 609463; Uniprot ID:MKL2_HUMAN; ENSEMBL ID: ENSG00000186260; HGNC ID: 29819 |
Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.49143
Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
---|---|---|---|
embryoid body | 1 / 70761 | 14 | |
blastocyst | 3 / 62319 | 48 | |
fetus | 24 / 564012 | 42 | |
neonate | 0 / 31097 | 0 | |
infant | 0 / 23620 | 0 | |
juvenile | 0 / 55556 | 0 | |
adult | 87 / 1939121 | 44 |
Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
---|---|---|---|
adrenal tumor | 1 / 12794 | 78 | |
bladder carcinoma | 1 / 17475 | 57 | |
breast (mammary gland) tumor | 2 / 94178 | 21 | |
cervical tumor | 0 / 34366 | 0 | |
chondrosarcoma | 2 / 82823 | 24 | |
colorectal tumor | 2 / 114246 | 17 | |
esophageal tumor | 0 / 17290 | 0 | |
gastrointestinal tumor | 1 / 119369 | 8 | |
germ cell tumor | 5 / 263845 | 18 | |
glioma | 4 / 106883 | 37 | |
head and neck tumor | 9 / 136302 | 66 | |
kidney tumor | 3 / 68959 | 43 | |
leukemia | 0 / 95842 | 0 | |
liver tumor | 4 / 96359 | 41 | |
lung tumor | 1 / 103127 | 9 | |
lymphoma | 1 / 71755 | 13 | |
non-neoplasia | 8 / 97250 | 82 | |
normal | 191 / 3360307 | 56 | |
ovarian tumor | 2 / 76682 | 26 | |
pancreatic tumor | 1 / 104616 | 9 | |
primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
prostate cancer | 4 / 102680 | 38 | |
retinoblastoma | 0 / 46356 | 0 | |
skin tumor | 4 / 124949 | 32 | |
soft tissue/muscle tissue tumor | 5 / 125191 | 39 | |
uterine tumor | 2 / 90257 | 22 |
Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
---|---|---|---|
adipose tissue | 0 / 13106 | 0 | |
adrenal gland | 1 / 33197 | 30 | |
ascites | 0 / 40015 | 0 | |
bladder | 2 / 29757 | 67 | |
blood | 0 / 123478 | 0 | |
bone | 2 / 71655 | 27 | |
bone marrow | 0 / 48801 | 0 | |
brain | 92 / 1100989 | 83 | |
cervix | 2 / 48171 | 41 | |
connective tissue | 3 / 149255 | 20 | |
ear | 4 / 16212 | 246 | |
embryonic tissue | 7 / 215722 | 32 | |
esophagus | 0 / 20209 | 0 | |
eye | 10 / 211054 | 47 | |
heart | 3 / 89626 | 33 | |
intestine | 6 / 234472 | 25 | |
kidney | 8 / 211777 | 37 | |
larynx | 4 / 24145 | 165 | |
liver | 5 / 207743 | 24 | |
lung | 9 / 336974 | 26 | |
lymph | 0 / 44270 | 0 | |
lymph node | 2 / 91610 | 21 | |
mammary gland | 11 / 153271 | 71 | |
mouth | 4 / 67052 | 59 | |
muscle | 5 / 107715 | 46 | |
nerve | 1 / 15768 | 63 | |
ovary | 3 / 102051 | 29 | |
pancreas | 10 / 214812 | 46 | |
parathyroid | 0 / 20539 | 0 | |
pharynx | 1 / 41328 | 24 | |
pituitary gland | 2 / 16585 | 120 | |
placenta | 7 / 280825 | 24 | |
prostate | 8 / 189345 | 42 | |
salivary gland | 3 / 20155 | 148 | |
skin | 4 / 210574 | 18 | |
spleen | 1 / 53952 | 18 | |
stomach | 2 / 96619 | 20 | |
testis | 16 / 330442 | 48 | |
thymus | 8 / 81131 | 98 | |
thyroid | 2 / 47473 | 42 | |
tonsil | 0 / 16999 | 0 | |
trachea | 6 / 52413 | 114 | |
umbilical cord | 0 / 13680 | 0 | |
uterus | 15 / 232878 | 64 | |
vascular | 1 / 51780 | 19 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 218259_at
Cell line | Expression level | Expression bar |
---|---|---|
721_B_lymphoblasts | 21.95 | |
Adipocyte | 16.15 | |
AdrenalCortex | 18 | |
Adrenalgland | 27.65 | |
Amygdala | 813.55 | |
Appendix | 17.5 | |
AtrioventricularNode | 16.4 | |
BDCA4+_DentriticCells | 18.4 | |
Bonemarrow | 15.25 | |
BronchialEpithelialCells | 27.15 | |
CD105+_Endothelial | 16.75 | |
CD14+_Monocytes | 14.55 | |
CD19+_BCells(neg._sel.) | 16.7 | |
CD33+_Myeloid | 19.3 | |
CD34+ | 56.25 | |
CD4+_Tcells | 18.6 | |
CD56+_NKCells | 18.1 | |
CD71+_EarlyErythroid | 14.45 | |
CD8+_Tcells | 25.75 | |
CardiacMyocytes | 22.65 | |
Caudatenucleus | 202.85 | |
Cerebellum | 13 | |
CerebellumPeduncles | 19.15 | |
CiliaryGanglion | 12.7 | |
CingulateCortex | 260.4 | |
Colorectaladenocarcinoma | 15.25 | |
DorsalRootGanglion | 13.25 | |
FetalThyroid | 29.05 | |
Fetalbrain | 161.05 | |
Fetalliver | 13.4 | |
Fetallung | 44.65 | |
GlobusPallidus | 175.2 | |
Heart | 19.95 | |
Hypothalamus | 124.25 | |
Kidney | 13.65 | |
Leukemia_chronicMyelogenousK-562 | 20.9 | |
Leukemia_promyelocytic-HL-60 | 14.8 | |
Leukemialymphoblastic(MOLT-4) | 41.8 | |
Liver | 22.2 | |
Lung | 38.75 | |
Lymphnode | 56.85 | |
Lymphoma_burkitts(Daudi) | 20.05 | |
Lymphoma_burkitts(Raji) | 23.3 | |
MedullaOblongata | 231.6 | |
OccipitalLobe | 372.6 | |
OlfactoryBulb | 13.5 | |
Ovary | 13.4 | |
Pancreas | 21.9 | |
PancreaticIslet | 61.25 | |
ParietalLobe | 185.9 | |
Pituitary | 88.75 | |
Placenta | 131.65 | |
Pons | 169.7 | |
PrefrontalCortex | 1698.65 | |
Prostate | 100.8 | |
Salivarygland | 29.05 | |
SkeletalMuscle | 21.45 | |
Skin | 18.6 | |
SmoothMuscle | 17.5 | |
Spinalcord | 19.1 | |
SubthalamicNucleus | 325.05 | |
SuperiorCervicalGanglion | 21.95 | |
TemporalLobe | 224.05 | |
Testis | 43.5 | |
TestisGermCell | 94.35 | |
TestisIntersitial | 16.95 | |
TestisLeydigCell | 17.95 | |
TestisSeminiferousTubule | 37.5 | |
Thalamus | 39.35 | |
Thymus | 32.75 | |
Thyroid | 165.15 | |
Tongue | 17.4 | |
Tonsil | 20.35 | |
Trachea | 69.15 | |
TrigeminalGanglion | 17.9 | |
Uterus | 152.8 | |
UterusCorpus | 33.05 | |
WholeBlood | 17.15 | |
Wholebrain | 280 | |
colon | 112.05 | |
pineal_day | 24.94 | |
pineal_night | 29.72 | |
retina | 59.4 | |
small_intestine | 121.85 |
Human Whole Brain Microarrayview in Allen Brain Atlas
- Probe name: A_23_P54556
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue | Expression(mean ± stddev) | Expression Bar |
---|---|---|
Amygdala | 11.4 ± 0.66 | |
Basal Forebrain | 10.46 ± 0.76 | |
Basal Part of Pons | 9.59 ± 0.3 | |
Cerebellar Cortex | 9.62 ± 0.27 | |
Cerebellar Nuclei | 9.1 ± 0.59 | |
Claustrum | 11.14 ± 0.42 | |
Epithalamus | 9.62 ± 0.71 | |
Frontal Lobe | 10.66 ± 0.58 | |
Globus Pallidus | 8.5 ± 1.48 | |
Hypothalamus | 10.34 ± 0.53 | |
Insula | 11.05 ± 0.5 | |
Limbic Lobe | 10.91 ± 0.88 | |
Mesencephalon | 10.03 ± 0.74 | |
Myelencephalon | 10.29 ± 0.47 | |
Occipital Lobe | 9.87 ± 1.01 | |
Parietal Lobe | 10.53 ± 0.6 | |
Pontine Tegmentum | 10.57 ± 0.72 | |
Striatum | 10.45 ± 1.14 | |
Subthalamus | 9.89 ± 0.11 | |
Temporal Lobe | 10.85 ± 0.44 | |
Thalamus | 9.86 ± 0.54 | |
White Matter | 8.24 ± 1.06 |
Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
---|---|---|---|---|
Mkl2 | CB | Cerebellum | 100 | |
100 | ||||
Mkl2 | CTX | Cerebral cortex | 100 | |
100 | ||||
Mkl2 | HIP | Hippocampal region | 100 | |
100 | ||||
Mkl2 | HPF | Hippocampal formation | 100 | |
100 | ||||
Mkl2 | HY | Hypothalamus | 100 | |
100 | ||||
Mkl2 | LSX | Lateral septal complex | 100 | |
100 | ||||
Mkl2 | MB | Midbrain | 100 | |
100 | ||||
Mkl2 | MY | Medulla | 100 | |
100 | ||||
Mkl2 | OLF | Olfactory bulb | 100 | |
100 | ||||
Mkl2 | P | Pons | 100 | |
100 | ||||
Mkl2 | PAL | Pallidum | 100 | |
100 | ||||
Mkl2 | RHP | Retrohippocampal region | 100 | |
100 | ||||
Mkl2 | sAMY | Striatum-like amygdalar nuclei | 100 | |
100 | ||||
Mkl2 | STR | Striatum | 100 | |
100 | ||||
Mkl2 | STRd | Striatum dorsal region | 100 | |
100 | ||||
Mkl2 | STRv | Striatum ventral region | 100 | |
100 | ||||
Mkl2 | TH | Thalamus | 100 | |
100 |
Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
---|---|---|---|---|---|
MKL2_HUMAN_279 | 10 | 279 | 288 | SKKCKDPKPR | PRIDE |
PAp00096062 | 21 | 631 | 651 | HGSLGSSIKDEASLPDCSSSR | Peptide Atlas |