AutismKB 2.0

Annotation Detail for MTUS1


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Basic Information Top
Gene Symbol:MTUS1 ( ATBP,ATIP,DKFZp586D1519,DKFZp686F20243,FLJ14295,KIAA1288,MP44,MTSG1 )
Gene Full Name: microtubule associated tumor suppressor 1
Band: 8p22
Quick LinksEntrez ID:57509; OMIM: 609589; Uniprot ID:MTUS1_HUMAN; ENSEMBL ID: ENSG00000129422; HGNC ID: 29789
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus47 / 56401283
neonate4 / 31097128
infant2 / 2362084
juvenile1 / 5555617
adult181 / 193912193
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma3 / 17475171
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor9 / 11424678
esophageal tumor1 / 1729057
gastrointestinal tumor6 / 11936950
germ cell tumor22 / 26384583
glioma7 / 10688365
head and neck tumor28 / 136302205
kidney tumor9 / 68959130
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia11 / 97250113
normal451 / 3360307134
ovarian tumor1 / 7668213
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS11 / 12568087
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor7 / 12494956
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue6 / 13106457
adrenal gland3 / 3319790
ascites1 / 4001524
bladder2 / 2975767
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain243 / 1100989220
cervix1 / 4817120
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus1 / 2020949
eye20 / 21105494
heart18 / 89626200
intestine19 / 23447281
kidney23 / 211777108
larynx3 / 24145124
liver3 / 20774314
lung33 / 33697497
lymph0 / 442700 
lymph node0 / 916100 
mammary gland13 / 15327184
mouth20 / 67052298
muscle9 / 10771583
nerve0 / 157680 
ovary1 / 1020519
pancreas19 / 21481288
parathyroid5 / 20539243
pharynx7 / 41328169
pituitary gland0 / 165850 
placenta45 / 280825160
prostate21 / 189345110
salivary gland0 / 201550 
skin16 / 21057475
spleen2 / 5395237
stomach10 / 96619103
testis19 / 33044257
thymus5 / 8113161
thyroid6 / 47473126
tonsil0 / 169990 
trachea17 / 52413324
umbilical cord4 / 13680292
uterus9 / 23287838
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212095_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts41.9
Adipocyte8.25
AdrenalCortex11.85
Adrenalgland7.65
Amygdala11.2
Appendix10.7
AtrioventricularNode10.3
BDCA4+_DentriticCells7.8
Bonemarrow9.05
BronchialEpithelialCells10.05
CD105+_Endothelial8.35
CD14+_Monocytes8.5
CD19+_BCells(neg._sel.)8.5
CD33+_Myeloid10.6
CD34+9.65
CD4+_Tcells8.9
CD56+_NKCells9.45
CD71+_EarlyErythroid8.1
CD8+_Tcells8.4
CardiacMyocytes12.4
Caudatenucleus9.05
Cerebellum27.65
CerebellumPeduncles199.95
CiliaryGanglion11.25
CingulateCortex21.55
Colorectaladenocarcinoma8.5
DorsalRootGanglion7.7
FetalThyroid9.1
Fetalbrain9.85
Fetalliver9.05
Fetallung9
GlobusPallidus9.9
Heart12.15
Hypothalamus40.2
Kidney8.1
Leukemia_chronicMyelogenousK-5627.7
Leukemia_promyelocytic-HL-608.4
Leukemialymphoblastic(MOLT-4)6.9
Liver13.35
Lung10.6
Lymphnode8.55
Lymphoma_burkitts(Daudi)11.7
Lymphoma_burkitts(Raji)13.6
MedullaOblongata63.65
OccipitalLobe105.25
OlfactoryBulb30.45
Ovary25.6
Pancreas24.2
PancreaticIslet81.65
ParietalLobe42.6
Pituitary16.85
Placenta16.25
Pons12.35
PrefrontalCortex17.15
Prostate15.35
Salivarygland8.1
SkeletalMuscle22.2
Skin7.65
SmoothMuscle9.55
Spinalcord13.3
SubthalamicNucleus10
SuperiorCervicalGanglion12.15
TemporalLobe9.95
Testis8.5
TestisGermCell8.45
TestisIntersitial8.35
TestisLeydigCell9.85
TestisSeminiferousTubule8.5
Thalamus9.2
Thymus7.6
Thyroid11.55
Tongue15
Tonsil10
Trachea12.95
TrigeminalGanglion11.3
Uterus7.95
UterusCorpus13.4
WholeBlood9.2
Wholebrain11.45
colon19.55
pineal_day298.68
pineal_night313.74
retina55.725
small_intestine9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_6808_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.67 ± 0.6
Basal Forebrain7.5 ± 0.42
Basal Part of Pons6.88 ± 0.61
Cerebellar Cortex7.44 ± 0.17
Cerebellar Nuclei7.95 ± 0.45
Claustrum6.89 ± 0.39
Epithalamus6.97 ± 0.53
Frontal Lobe6.85 ± 0.65
Globus Pallidus8.13 ± 0.67
Hypothalamus6.65 ± 0.48
Insula6.57 ± 0.48
Limbic Lobe6.69 ± 0.62
Mesencephalon7.14 ± 0.59
Myelencephalon7.08 ± 0.57
Occipital Lobe7.18 ± 0.5
Parietal Lobe6.93 ± 0.6
Pontine Tegmentum7.21 ± 0.44
Striatum7.32 ± 0.76
Subthalamus7.05 ± 0.41
Temporal Lobe6.79 ± 0.47
Thalamus7.38 ± 0.37
White Matter9.24 ± 0.46
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mtus1CBCerebellum76.2
100
Mtus1CTXCerebral cortex7.16
4.97
Mtus1HIPHippocampal region6.34
6.55
Mtus1HPFHippocampal formation6.63
6.1
Mtus1HYHypothalamus2.68
2.38
Mtus1LSXLateral septal complex1.14
0.71
Mtus1MBMidbrain4.59
4.64
Mtus1MYMedulla13.24
14.68
Mtus1OLFOlfactory bulb20.3
17.66
Mtus1PPons9.42
9.79
Mtus1PALPallidum5.84
5.32
Mtus1RHPRetrohippocampal region7.26
5.57
Mtus1sAMYStriatum-like amygdalar nuclei8.16
7.01
Mtus1STRStriatum9.22
7.26
Mtus1STRdStriatum dorsal region12.36
9.73
Mtus1STRvStriatum ventral region5.49
4.18
Mtus1THThalamus11.59
9.79
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MTUS1_HUMAN_413 13 413 425 VTFSVSPIEATEK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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