AutismKB 2.0

Annotation Detail for XPO5


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Basic Information Top
Gene Symbol:XPO5 ( FLJ14239,FLJ32057,FLJ45606,KIAA1291 )
Gene Full Name: exportin 5
Band: 6p21.1
Quick LinksEntrez ID:57510; OMIM: 607845; Uniprot ID:XPO5_HUMAN; ENSEMBL ID: ENSG00000124571; HGNC ID: 17675
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body12 / 70761169
blastocyst9 / 62319144
fetus45 / 56401279
neonate0 / 310970 
infant2 / 2362084
juvenile12 / 55556215
adult159 / 193912181
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor9 / 9417895
cervical tumor3 / 3436687
chondrosarcoma5 / 8282360
colorectal tumor6 / 11424652
esophageal tumor2 / 17290115
gastrointestinal tumor24 / 119369201
germ cell tumor42 / 263845159
glioma3 / 10688328
head and neck tumor20 / 136302146
kidney tumor1 / 6895914
leukemia6 / 9584262
liver tumor24 / 96359249
lung tumor7 / 10312767
lymphoma9 / 71755125
non-neoplasia4 / 9725041
normal220 / 336030765
ovarian tumor16 / 76682208
pancreatic tumor9 / 10461686
primitive neuroectodermal tumor of the CNS16 / 125680127
prostate cancer5 / 10268048
retinoblastoma9 / 46356194
skin tumor15 / 124949120
soft tissue/muscle tissue tumor10 / 12519179
uterine tumor16 / 90257177
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites9 / 40015224
bladder0 / 297570 
blood9 / 12347872
bone5 / 7165569
bone marrow2 / 4880140
brain67 / 110098960
cervix3 / 4817162
connective tissue8 / 14925553
ear0 / 162120 
embryonic tissue24 / 215722111
esophagus2 / 2020998
eye27 / 211054127
heart5 / 8962655
intestine18 / 23447276
kidney12 / 21177756
larynx1 / 2414541
liver27 / 207743129
lung18 / 33697453
lymph8 / 44270180
lymph node16 / 91610174
mammary gland11 / 15327171
mouth17 / 67052253
muscle6 / 10771555
nerve2 / 15768126
ovary16 / 102051156
pancreas16 / 21481274
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland3 / 16585180
placenta20 / 28082571
prostate12 / 18934563
salivary gland1 / 2015549
skin22 / 210574104
spleen2 / 5395237
stomach6 / 9661962
testis62 / 330442187
thymus5 / 8113161
thyroid1 / 4747321
tonsil0 / 169990 
trachea5 / 5241395
umbilical cord0 / 136800 
uterus32 / 232878137
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15005_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.19 ± 0.11
Basal Forebrain7.11 ± 0.18
Basal Part of Pons6.91 ± 0.19
Cerebellar Cortex6.91 ± 0.16
Cerebellar Nuclei6.97 ± 0.25
Claustrum7.43 ± 0.33
Epithalamus6.83 ± 0.25
Frontal Lobe7 ± 0.23
Globus Pallidus6.69 ± 0.08
Hypothalamus6.9 ± 0.32
Insula7 ± 0.25
Limbic Lobe7.15 ± 0.28
Mesencephalon7.07 ± 0.27
Myelencephalon7.05 ± 0.28
Occipital Lobe7.23 ± 0.33
Parietal Lobe7.08 ± 0.22
Pontine Tegmentum7.09 ± 0.28
Striatum7.46 ± 0.23
Subthalamus6.76 ± 0.02
Temporal Lobe7.06 ± 0.24
Thalamus7.05 ± 0.23
White Matter6.69 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Xpo5CBCerebellum9.45
9.84
Xpo5CTXCerebral cortex23.84
15.86
Xpo5HIPHippocampal region18.06
19.17
Xpo5HPFHippocampal formation12.97
12.43
Xpo5HYHypothalamus4.87
3.75
Xpo5LSXLateral septal complex6.02
3.6
Xpo5MBMidbrain7.22
6.25
Xpo5MYMedulla9.89
8.96
Xpo5OLFOlfactory bulb30.44
23.56
Xpo5PPons8.04
7.29
Xpo5PALPallidum8.61
7.05
Xpo5RHPRetrohippocampal region5.89
4.49
Xpo5sAMYStriatum-like amygdalar nuclei15.63
11.28
Xpo5STRStriatum9.57
6.69
Xpo5STRdStriatum dorsal region5.38
3.86
Xpo5STRvStriatum ventral region22.78
14.73
Xpo5THThalamus14.34
11.63
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00003275 16 381 396 HEILSRDPLLLAIIPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018