AutismKB 2.0

Annotation Detail for COG6


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Basic Information Top
Gene Symbol:COG6 ( COD2,DKFZp313D191,KIAA1134 )
Gene Full Name: component of oligomeric golgi complex 6
Band: 13q14.11
Quick LinksEntrez ID:57511; OMIM: 606977; Uniprot ID:COG6_HUMAN; ENSEMBL ID: ENSG00000133103; HGNC ID: 18621
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus25 / 56401244
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult59 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor3 / 3436687
chondrosarcoma2 / 8282324
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor11 / 26384541
glioma1 / 1068839
head and neck tumor7 / 13630251
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor6 / 9635962
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia2 / 9725020
normal130 / 336030738
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites0 / 400150 
bladder2 / 2975767
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain66 / 110098959
cervix3 / 4817162
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue4 / 21572218
esophagus0 / 202090 
eye3 / 21105414
heart2 / 8962622
intestine5 / 23447221
kidney5 / 21177723
larynx1 / 2414541
liver7 / 20774333
lung16 / 33697447
lymph0 / 442700 
lymph node2 / 9161021
mammary gland0 / 1532710 
mouth6 / 6705289
muscle4 / 10771537
nerve0 / 157680 
ovary0 / 1020510 
pancreas3 / 21481213
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta11 / 28082539
prostate5 / 18934526
salivary gland0 / 201550 
skin5 / 21057423
spleen1 / 5395218
stomach2 / 9661920
testis34 / 330442102
thymus6 / 8113173
thyroid1 / 4747321
tonsil0 / 169990 
trachea20 / 52413381
umbilical cord0 / 136800 
uterus6 / 23287825
vascular4 / 5178077
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P290692
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.93 ± 0.98
Basal Forebrain1.5 ± 0.19
Basal Part of Pons1.22 ± 0.32
Cerebellar Cortex1.32 ± 0.67
Cerebellar Nuclei1.77 ± 0.71
Claustrum2.37 ± 0.84
Epithalamus1.26 ± 0.72
Frontal Lobe1.33 ± 0.55
Globus Pallidus2.13 ± 0.33
Hypothalamus1.59 ± 0.7
Insula1.41 ± 0.47
Limbic Lobe1.51 ± 0.58
Mesencephalon1.65 ± 0.64
Myelencephalon1.52 ± 0.62
Occipital Lobe1.55 ± 0.56
Parietal Lobe1.49 ± 0.59
Pontine Tegmentum1.55 ± 0.65
Striatum1.66 ± 0.46
Subthalamus1.64 ± 0.6
Temporal Lobe1.44 ± 0.67
Thalamus1.47 ± 0.55
White Matter2.11 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Cog6CBCerebellum23.49
40.71
Cog6CTXCerebral cortex37.38
28.98
Cog6HIPHippocampal region22.53
25.68
Cog6HPFHippocampal formation27.62
27.33
Cog6HYHypothalamus4.96
4.24
Cog6LSXLateral septal complex4.41
3.15
Cog6MBMidbrain15.13
15.84
Cog6MYMedulla27.42
35.4
Cog6OLFOlfactory bulb27.49
22.01
Cog6PPons20.24
25.02
Cog6PALPallidum12.83
13.4
Cog6RHPRetrohippocampal region39.66
32.32
Cog6sAMYStriatum-like amygdalar nuclei16.15
12.58
Cog6STRStriatum10.34
7.79
Cog6STRdStriatum dorsal region10.04
7.82
Cog6STRvStriatum ventral region12.65
8.41
Cog6THThalamus25.11
22.42
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00025814 27 365 391 HVTTQGVEENIQEVVGHITEGVCRPLK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018