Annotation Detail for HECW2
Basic Information Top
| Gene Symbol: | HECW2 ( DKFZp686M17164,NEDL2 ) |
|---|---|
| Gene Full Name: | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 |
| Band: | 2q32.3 |
| Quick Links | Entrez ID:57520; OMIM: NA; Uniprot ID:HECW2_HUMAN; ENSEMBL ID: ENSG00000138411; HGNC ID: 29853 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.654742
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 3 / 70761 | 42 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 13 / 564012 | 23 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 11 / 1939121 | 5 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 1 / 34366 | 29 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 2 / 114246 | 17 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 0 / 263845 | 0 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 46 / 3360307 | 13 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 10 / 1100989 | 9 | |
| cervix | 1 / 48171 | 20 | |
| connective tissue | 1 / 149255 | 6 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 5 / 215722 | 23 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 0 / 211054 | 0 | |
| heart | 0 / 89626 | 0 | |
| intestine | 3 / 234472 | 12 | |
| kidney | 3 / 211777 | 14 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 0 / 336974 | 0 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 2 / 91610 | 21 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 5 / 107715 | 46 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 2 / 214812 | 9 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 2 / 53952 | 37 | |
| stomach | 0 / 96619 | 0 | |
| testis | 7 / 330442 | 21 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 3 / 51780 | 57 |  |
Microarray in - Probe name: A_23_P50974
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 6.63 ± 0.26 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.61 ± 0.16 | |
| Basal Part of Pons | 6.72 ± 0.38 | |
| Cerebellar Cortex | 6.63 ± 0.39 | |
| Cerebellar Nuclei | 6.87 ± 0.27 | |
| Claustrum | 6.36 ± 0.45 | |
| Epithalamus | 5.9 ± 0.5 | |
| Frontal Lobe | 6.56 ± 0.35 | |
| Globus Pallidus | 6.1 ± 0.46 | |
| Hypothalamus | 6.15 ± 0.44 | |
| Insula | 6.57 ± 0.32 | |
| Limbic Lobe | 6.83 ± 0.39 | |
| Mesencephalon | 6.58 ± 0.4 | |
| Myelencephalon | 6.57 ± 0.42 | |
| Occipital Lobe | 7.06 ± 0.3 | |
| Parietal Lobe | 6.7 ± 0.35 | |
| Pontine Tegmentum | 6.69 ± 0.38 | |
| Striatum | 6.48 ± 0.4 | |
| Subthalamus | 6.2 ± 0.7 | |
| Temporal Lobe | 6.7 ± 0.35 | |
| Thalamus | 6.54 ± 0.3 | |
| White Matter | 7.19 ± 0.48 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Hecw2 | CB | Cerebellum | 12.4 | |
| 13.24 | | |||
| Hecw2 | CTX | Cerebral cortex | 68.64 | |
| 51.35 | | |||
| Hecw2 | HIP | Hippocampal region | 8.98 | |
| 8.8 | | |||
| Hecw2 | HPF | Hippocampal formation | 17.07 | |
| 15.16 | | |||
| Hecw2 | HY | Hypothalamus | 2.45 | |
| 2.05 | | |||
| Hecw2 | LSX | Lateral septal complex | 1.3 | |
| 0.93 | | |||
| Hecw2 | MB | Midbrain | 6.75 | |
| 6.44 | | |||
| Hecw2 | MY | Medulla | 10.95 | |
| 11.68 | | |||
| Hecw2 | OLF | Olfactory bulb | 26.21 | |
| 20.82 | | |||
| Hecw2 | P | Pons | 7.81 | |
| 8.45 | | |||
| Hecw2 | PAL | Pallidum | 2.71 | |
| 2.12 | | |||
| Hecw2 | RHP | Retrohippocampal region | 28.93 | |
| 22.37 | | |||
| Hecw2 | sAMY | Striatum-like amygdalar nuclei | 0.79 | |
| 0.53 | | |||
| Hecw2 | STR | Striatum | 10.3 | |
| 6.89 | | |||
| Hecw2 | STRd | Striatum dorsal region | 13.03 | |
| 8.8 | | |||
| Hecw2 | STRv | Striatum ventral region | 9.32 | |
| 6.03 | | |||
| Hecw2 | TH | Thalamus | 19.23 | |
| 16.16 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00028982 | 7 | 1537 | 1543 | AHTCFNR | Peptide Atlas |