Annotation Detail for SRGAP1
Basic Information Top
| Gene Symbol: | SRGAP1 ( ARHGAP13,FLJ22166,KIAA1304 ) |
|---|---|
| Gene Full Name: | SLIT-ROBO Rho GTPase activating protein 1 |
| Band: | 12q14.2 |
| Quick Links | Entrez ID:57522; OMIM: 606523; Uniprot ID:SRGP1_HUMAN; ENSEMBL ID: ENSG00000196935; HGNC ID: 17382 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.593803
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 31 / 564012 | 54 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 53 / 1939121 | 27 | |
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 11 / 564012 | 19 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 11 / 1939121 | 5 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 5 / 82823 | 60 | |
| colorectal tumor | 4 / 114246 | 35 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 3 / 263845 | 11 | |
| glioma | 4 / 106883 | 37 | |
| head and neck tumor | 4 / 136302 | 29 | |
| kidney tumor | 10 / 68959 | 145 | |
| leukemia | 1 / 95842 | 10 | |
| liver tumor | 3 / 96359 | 31 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 75 / 3360307 | 22 | |
| ovarian tumor | 4 / 76682 | 52 | |
| pancreatic tumor | 1 / 104616 | 9 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 22 / 124949 | 176 | |
| soft tissue/muscle tissue tumor | 4 / 125191 | 31 | |
| uterine tumor | 2 / 90257 | 22 | |
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 2 / 114246 | 17 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 | |
| germ cell tumor | 5 / 263845 | 18 | |
| glioma | 2 / 106883 | 18 | |
| head and neck tumor | 3 / 136302 | 22 | |
| kidney tumor | 1 / 68959 | 14 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 0 / 97250 | 0 | |
| normal | 21 / 3360307 | 6 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 1 / 102680 | 9 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 1 / 124949 | 8 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 2 / 29757 | 67 | |
| blood | 0 / 123478 | 0 | |
| bone | 4 / 71655 | 55 | |
| bone marrow | 2 / 48801 | 40 | |
| brain | 29 / 1100989 | 26 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 4 / 149255 | 26 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 3 / 215722 | 13 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 7 / 211054 | 33 | |
| heart | 1 / 89626 | 11 | |
| intestine | 5 / 234472 | 21 | |
| kidney | 18 / 211777 | 84 | |
| larynx | 0 / 24145 | 0 | |
| liver | 7 / 207743 | 33 | |
| lung | 9 / 336974 | 26 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 1 / 91610 | 10 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 3 / 67052 | 44 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 4 / 102051 | 39 | |
| pancreas | 6 / 214812 | 27 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 1 / 280825 | 3 | |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 22 / 210574 | 104 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 2 / 96619 | 20 | |
| testis | 4 / 330442 | 12 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 4 / 47473 | 84 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 1 / 52413 | 19 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 4 / 232878 | 17 | |
| vascular | 1 / 51780 | 19 | |
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 3 / 1100989 | 2 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 3 / 215722 | 13 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 2 / 211054 | 9 | |
| heart | 0 / 89626 | 0 | |
| intestine | 2 / 234472 | 8 | |
| kidney | 1 / 211777 | 4 | |
| larynx | 0 / 24145 | 0 | |
| liver | 1 / 207743 | 4 | |
| lung | 2 / 336974 | 5 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 2 / 153271 | 13 | |
| mouth | 1 / 67052 | 14 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 2 / 210574 | 9 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 1 / 96619 | 10 | |
| testis | 1 / 330442 | 3 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 2 / 47473 | 42 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 2 / 51780 | 38 | |
Microarray in - Probe name: CUST_9519_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 4.54 ± 1.01 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.96 ± 0.27 | |
| Basal Part of Pons | 3.57 ± 0.62 | |
| Cerebellar Cortex | 4.06 ± 0.5 | |
| Cerebellar Nuclei | 4.92 ± 0.67 | |
| Claustrum | 4.47 ± 0.84 | |
| Epithalamus | 5.17 ± 0.73 | |
| Frontal Lobe | 4.23 ± 0.85 | |
| Globus Pallidus | 5.77 ± 0.28 | |
| Hypothalamus | 4.72 ± 0.5 | |
| Insula | 4.35 ± 0.69 | |
| Limbic Lobe | 4.04 ± 0.91 | |
| Mesencephalon | 4.91 ± 0.68 | |
| Myelencephalon | 4.6 ± 0.8 | |
| Occipital Lobe | 4.37 ± 0.97 | |
| Parietal Lobe | 4.21 ± 0.84 | |
| Pontine Tegmentum | 4.66 ± 0.74 | |
| Striatum | 6.26 ± 0.78 | |
| Subthalamus | 4.55 ± 0.14 | |
| Temporal Lobe | 4.21 ± 0.69 | |
| Thalamus | 5.1 ± 0.46 | |
| White Matter | 5.47 ± 0.49 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Srgap1 | CB | Cerebellum | 28.07 | |
| 100 | | |||
| Srgap1 | CTX | Cerebral cortex | 30.72 | |
| 25.12 | | |||
| Srgap1 | HIP | Hippocampal region | 32.1 | |
| 45.62 | | |||
| Srgap1 | HPF | Hippocampal formation | 37.19 | |
| 43.68 | | |||
| Srgap1 | HY | Hypothalamus | 27.97 | |
| 25.29 | | |||
| Srgap1 | LSX | Lateral septal complex | 44.49 | |
| 38.22 | | |||
| Srgap1 | MB | Midbrain | 35.88 | |
| 39.17 | | |||
| Srgap1 | MY | Medulla | 38.16 | |
| 45.46 | | |||
| Srgap1 | OLF | Olfactory bulb | 37.65 | |
| 36.04 | | |||
| Srgap1 | P | Pons | 31.6 | |
| 36.97 | | |||
| Srgap1 | PAL | Pallidum | 38.27 | |
| 40.51 | | |||
| Srgap1 | RHP | Retrohippocampal region | 49.98 | |
| 43.41 | | |||
| Srgap1 | sAMY | Striatum-like amygdalar nuclei | 71.94 | |
| 64.11 | | |||
| Srgap1 | STR | Striatum | 79.82 | |
| 73.62 | | |||
| Srgap1 | STRd | Striatum dorsal region | 98.85 | |
| 94.87 | | |||
| Srgap1 | STRv | Striatum ventral region | 51.42 | |
| 41.55 | | |||
| Srgap1 | TH | Thalamus | 83.22 | |
| 91.47 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00080837 | 12 | 43 | 54 | VQLLQDLQDFFR | Peptide Atlas |