AutismKB 2.0

Annotation Detail for PTK6


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Basic Information Top
Gene Symbol:PTK6 ( BRK,FLJ42088 )
Gene Full Name: PTK6 protein tyrosine kinase 6
Band: 20q13.33
Quick LinksEntrez ID:5753; OMIM: 602004; Uniprot ID:PTK6_HUMAN; ENSEMBL ID: ENSG00000101213; HGNC ID: 9617
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult25 / 193912112
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor3 / 9417831
cervical tumor3 / 3436687
chondrosarcoma1 / 8282312
colorectal tumor9 / 11424678
esophageal tumor3 / 17290173
gastrointestinal tumor9 / 11936975
germ cell tumor0 / 2638450 
glioma2 / 10688318
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal24 / 33603077
ovarian tumor0 / 766820 
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder3 / 29757100
blood2 / 12347816
bone0 / 716550 
bone marrow0 / 488010 
brain3 / 11009892
cervix9 / 48171186
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus3 / 20209148
eye0 / 2110540 
heart1 / 8962611
intestine18 / 23447276
kidney1 / 2117774
larynx0 / 241450 
liver1 / 2077434
lung3 / 3369748
lymph0 / 442700 
lymph node8 / 9161087
mammary gland3 / 15327119
mouth9 / 67052134
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas7 / 21481232
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach2 / 9661920
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206482_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.1
Adipocyte7.15
AdrenalCortex9.45
Adrenalgland6.65
Amygdala7.2
Appendix8.95
AtrioventricularNode7.55
BDCA4+_DentriticCells6.95
Bonemarrow8.25
BronchialEpithelialCells12.35
CD105+_Endothelial7.2
CD14+_Monocytes8
CD19+_BCells(neg._sel.)7.5
CD33+_Myeloid8.85
CD34+8.75
CD4+_Tcells7.6
CD56+_NKCells8.1
CD71+_EarlyErythroid7.1
CD8+_Tcells6.5
CardiacMyocytes13.4
Caudatenucleus6.6
Cerebellum5.95
CerebellumPeduncles9.1
CiliaryGanglion6.7
CingulateCortex7.75
Colorectaladenocarcinoma10.35
DorsalRootGanglion8.45
FetalThyroid7.4
Fetalbrain6.95
Fetalliver6.6
Fetallung5.4
GlobusPallidus6.05
Heart12.6
Hypothalamus7.45
Kidney6.85
Leukemia_chronicMyelogenousK-5626.55
Leukemia_promyelocytic-HL-606.5
Leukemialymphoblastic(MOLT-4)5.55
Liver11.65
Lung7.95
Lymphnode5.9
Lymphoma_burkitts(Daudi)9.75
Lymphoma_burkitts(Raji)11.7
MedullaOblongata6.55
OccipitalLobe6.5
OlfactoryBulb5.6
Ovary5.5
Pancreas8.75
PancreaticIslet7.95
ParietalLobe8.3
Pituitary8.6
Placenta7.1
Pons7.4
PrefrontalCortex8.7
Prostate8.25
Salivarygland6.25
SkeletalMuscle11.75
Skin7.2
SmoothMuscle8.25
Spinalcord7.75
SubthalamicNucleus7.1
SuperiorCervicalGanglion11.7
TemporalLobe7.05
Testis6.2
TestisGermCell5.75
TestisIntersitial6.35
TestisLeydigCell7.8
TestisSeminiferousTubule6.3
Thalamus7.7
Thymus5.4
Thyroid8.6
Tongue27.2
Tonsil7.95
Trachea6.05
TrigeminalGanglion14.45
Uterus5.75
UterusCorpus7.6
WholeBlood7.8
Wholebrain5.75
colon64.7
pineal_day9.08
pineal_night8.8
retina8.9
small_intestine7.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9314_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.45 ± 0.95
Basal Forebrain2.05 ± 0.26
Basal Part of Pons1.72 ± 0.42
Cerebellar Cortex1.87 ± 0.73
Cerebellar Nuclei2.34 ± 0.7
Claustrum2.91 ± 0.92
Epithalamus1.7 ± 0.77
Frontal Lobe1.85 ± 0.64
Globus Pallidus2.75 ± 0.74
Hypothalamus2 ± 0.64
Insula1.96 ± 0.51
Limbic Lobe2 ± 0.62
Mesencephalon2.19 ± 0.71
Myelencephalon2.04 ± 0.65
Occipital Lobe2.13 ± 0.73
Parietal Lobe2.02 ± 0.73
Pontine Tegmentum2.02 ± 0.67
Striatum2.18 ± 0.51
Subthalamus2.13 ± 0.66
Temporal Lobe1.92 ± 0.61
Thalamus1.99 ± 0.62
White Matter2.46 ± 0.25
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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