Annotation Detail for HACE1
Basic Information Top
| Gene Symbol: | HACE1 ( - ) |
|---|---|
| Gene Full Name: | HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 |
| Band: | 6q16.3 |
| Quick Links | Entrez ID:57531; OMIM: 610876; Uniprot ID:HACE1_HUMAN; ENSEMBL ID: ENSG00000085382; HGNC ID: 21033 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.434340
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 3 / 564012 | 5 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 32 / 1939121 | 16 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 1 / 94178 | 10 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 1 / 82823 | 12 | |
| colorectal tumor | 2 / 114246 | 17 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 1 / 119369 | 8 | |
| germ cell tumor | 2 / 263845 | 7 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 2 / 136302 | 14 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 1 / 96359 | 10 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 1 / 71755 | 13 | |
| non-neoplasia | 4 / 97250 | 41 | |
| normal | 57 / 3360307 | 16 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 3 / 104616 | 28 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 3 / 124949 | 24 | |
| soft tissue/muscle tissue tumor | 2 / 125191 | 15 | |
| uterine tumor | 1 / 90257 | 11 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 1 / 40015 | 24 | |
| bladder | 0 / 29757 | 0 | |
| blood | 0 / 123478 | 0 | |
| bone | 1 / 71655 | 13 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 36 / 1100989 | 32 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 5 / 215722 | 23 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 2 / 211054 | 9 | |
| heart | 1 / 89626 | 11 | |
| intestine | 2 / 234472 | 8 | |
| kidney | 4 / 211777 | 18 | |
| larynx | 0 / 24145 | 0 | |
| liver | 2 / 207743 | 9 | |
| lung | 2 / 336974 | 5 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 1 / 91610 | 10 | |
| mammary gland | 1 / 153271 | 6 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 1 / 107715 | 9 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 6 / 214812 | 27 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 1 / 41328 | 24 | |
| pituitary gland | 1 / 16585 | 60 |  |
| placenta | 12 / 280825 | 42 | |
| prostate | 0 / 189345 | 0 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 3 / 210574 | 14 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 0 / 96619 | 0 | |
| testis | 8 / 330442 | 24 | |
| thymus | 4 / 81131 | 49 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 3 / 52413 | 57 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 2 / 232878 | 8 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_10955_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 7.37 ± 0.18 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 7.12 ± 0.19 | |
| Basal Part of Pons | 7.21 ± 0.22 | |
| Cerebellar Cortex | 7.12 ± 0.3 | |
| Cerebellar Nuclei | 7.24 ± 0.23 | |
| Claustrum | 7.49 ± 0.32 | |
| Epithalamus | 6.94 ± 0.29 | |
| Frontal Lobe | 7.12 ± 0.29 | |
| Globus Pallidus | 6.83 ± 0.15 | |
| Hypothalamus | 7.17 ± 0.2 | |
| Insula | 7.11 ± 0.29 | |
| Limbic Lobe | 7.23 ± 0.33 | |
| Mesencephalon | 7.18 ± 0.28 | |
| Myelencephalon | 7.19 ± 0.29 | |
| Occipital Lobe | 7.47 ± 0.22 | |
| Parietal Lobe | 7.34 ± 0.28 | |
| Pontine Tegmentum | 7.22 ± 0.37 | |
| Striatum | 7.38 ± 0.32 | |
| Subthalamus | 8.01 ± 0.03 | |
| Temporal Lobe | 7.19 ± 0.27 | |
| Thalamus | 7.14 ± 0.25 | |
| White Matter | 7.18 ± 0.18 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Hace1 | CB | Cerebellum | 6.93 | |
| 6.78 | | |||
| Hace1 | CTX | Cerebral cortex | 81.07 | |
| 66.01 | | |||
| Hace1 | HIP | Hippocampal region | 39.26 | |
| 51.68 | | |||
| Hace1 | HPF | Hippocampal formation | 41.95 | |
| 46.45 | | |||
| Hace1 | HY | Hypothalamus | 7.32 | |
| 5.73 | | |||
| Hace1 | LSX | Lateral septal complex | 34.58 | |
| 28 | | |||
| Hace1 | MB | Midbrain | 13.28 | |
| 12.37 | | |||
| Hace1 | MY | Medulla | 21.58 | |
| 21.4 | | |||
| Hace1 | OLF | Olfactory bulb | 54.5 | |
| 48.46 | | |||
| Hace1 | P | Pons | 17.45 | |
| 15.99 | | |||
| Hace1 | PAL | Pallidum | 12.44 | |
| 10.11 | | |||
| Hace1 | RHP | Retrohippocampal region | 48.51 | |
| 39.86 | | |||
| Hace1 | sAMY | Striatum-like amygdalar nuclei | 29.63 | |
| 19.86 | | |||
| Hace1 | STR | Striatum | 46.54 | |
| 32.74 | | |||
| Hace1 | STRd | Striatum dorsal region | 52.97 | |
| 37.85 | | |||
| Hace1 | STRv | Striatum ventral region | 41.42 | |
| 26.51 | | |||
| Hace1 | TH | Thalamus | 10.29 | |
| 8.29 | |